1. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Configuration of the light probes. Measurement positions are shown. The light probes cover the bilateral fronto-temporal areas in order to measure the middle cerebral artery (MCA) territory. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

2. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Waveform and power spectrum of the near-infrared spectroscopy (NIRS) signals. (a) Time course of raw Total-Hb data measured by NIRS in the resting state and (b) an enlarged view. (c) A fast Fourier transform (FFT) was applied to the Total-Hb data. The peak of the power spectrum is observed at the frequency band of the cardiac oscillation. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

3. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Angiogram and N-isopropyl-p-[123I] iodoamphetamine (I123-IMP)-SPECT images before and after carotid artery stenting (CAS). (a) Angiogram shows severe stenosis of the left cervical internal carotid artery (ICA). (b) I123-IMP-SPECT demonstrates a decrease in cerebral blood flow (CBF) in the left MCA territory before CAS. (c) The ICA was dilated by CAS. (d) I123-IMP-SPECT demonstrates an increase in CBF in the left MCA territory caused by CAS. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

4. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Waveforms and power spectra of the pulse wave (before CAS). (a) Waveforms of pulse wave in the ischemic region and (b) in the contralateral region. (c) Power spectra of pulse wave in the ischemic region and (d) in the contralateral region. The peak in power spectrum of the pulse wave is defined as pulse-wave power. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

5. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Topogram of pulse-wave power before and after CAS. (a) Lower pulse-wave power in the ischemic region compared with the contralateral region is shown in the topogram before CAS. (b) An increase in pulse-wave power in the ischemic region is shown in the topogram after CAS. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

6. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Waveforms and power spectra of pulse wave (after CAS). (a) Waveforms of the pulse wave in the ischemic region and (b) in the contralateral region. (c) Power spectra of the pulse wave in the ischemic region and (d) in the contralateral region. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001

7. Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. Scatter plot of the mean pulse-wave power. The x-axis shows the mean of pulse-wave power on the ischemic side as defined by I123-IMP-SPECT. The y-axis shows the mean of pulse-wave power on the contralateral side. The results of cerebral ischemia are represented by closed circles, and the results after CAS are represented by open circles. Figure Legend: From: Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy J. Biomed. Opt. 2013;18(10):106001-106001. doi:10.1117/1.JBO.18.10.106001