1. BIRUNIPHARM LLP, PHARMACEUTICAL COMPANY, WAS ESTABLISHED ON DECEMBER 11, 2009 IN ALMATY AND IS EQUIPPED WITH MODERN TECHNOLOGICAL EQUIPMENT. About Company

2. PRODUCTION OF CONSUMABLES FOR HEMODIALYSIS - CONCENTRATED SOLUTIONS BF-A, BF(A1-А9), BF-B AND BF-CART. Company Activity

3. THE PRODUCTION CAPACITY PER YEAR IS: 600 THOUSAND SETS OF CONCENTRATED SOLUTIONS 200 THOUSAND CARTRIDGES Capacities

4. IN AUGUST 2010 AND JULY 2013 THE COMPANY SUCCESSFULLY OBTAINED THE INTERNATIONAL QUALITY CERTIFICATE ISO 13485:2003. Recognition of Company

5. Certificates

6. BF-A SOLUTION IS USED IN HEMODIALYSIS APPARATUSES WITH APPROPRIATE BF-B CONCENTRATED BASIC SOLUTION IN A RATIO OF BF-A : BF-B : PURIFIED WATER AS 1.000:1.225: 32.775. IT IS USED FOR THE ACID-ALKALI AND WATER- ELECTROLYTIC BALANCE IN HEMODIALYSIS TREATMENT, TREATMENT OF PATIENTS SUFFERING FROM CHRONIC AND ACUTE RENAL FAILURE, HYPERTENSION, INTOXICATION. BF-A concentrated acid solution for hemodialysis

7. BF-A1,BF-A2,BF-A3,BF-A4,BF-A5,BF-A6, BF-A7,BF- A8,BF-A9 SOLUTIONS ARE USED IN HEMODIALYSIS APPARATUSES WITH APPROPRIATE BF-B CONCENTRATED BASIC SOLUTION IN A RATIO OF BF(А1-А9) : BF-B : PURIFIED WATER AS 1.000: 1.225:32.775. IT IS USED FOR THE ACID-ALKALI AND WATER- ELECTROLYTIC BALANCE IN HEMODIALYSIS TREATMENT, TREATMENT OF PATIENTS SUFFERING FROM CHRONIC AND ACUTE RENAL FAILURE, HYPERTENSION, INTOXICATION. BF-A1, BF-A2, BF-A3, BF-A4, BF- A5, BF-A6, BF-A7, BF-A8, BF-А9 concentrated acid solutions for hemodialysis

8. BF-B SOLUTION IS USED IN HEMODIALYSIS APPARATUSES WITH APPROPRIATE BF-A CONCENTRATED ACID SOLUTION IN A RATIO OF BF-A : BF-B : PURIFIED WATER AS 1.000:1.225:32.775. IT IS USED FOR THE ACID-ALKALI AND WATER- ELECTROLYTIC BALANCE IN HEMODIALYSIS TREATMENT, TREATMENT OF PATIENTS SUFFERING FROM CHRONIC AND ACUTE RENAL FAILURE, HYPERTENSION, INTOXICATION. BF-B concentrated basic solution for hemodialysis

9. IONIC CONTENT IN ALL ACID SOLUTIONS WITH DIFFERENT CONTENTS OF K+ AND CA2+ IONS INGREDIENTS IN BF-A9 – PER 1 LITER: SODIUM CHLORIDE - 214.800 G. POTASSIUM CHLORIDE – 7.836 G. CALCIUM CHLORIDE (2H2O) - 9.005 G. MAGNESIUM CHLORIDE (6H2O) – 3.558 G. ACETIC ACID (99% -100%) – 6.310 G. PURIFIED WATER -1.000 LITERS Ingredients INGREDIENTS IN BF-A ACID SOLUTION PER 1 LITER SODIUM CHLORIDE - 214.800 G. POTASSIUM CHLORIDE – 2.612 G. CALCIUM CHLORIDE (2H2O) -7.720 G. MAGNESIUM CHLORIDE (6H2O) – 3.558 G. ACETIC ACID (99% -100%) - 4.207 G. PURIFIED WATER -1.000 LITERS INGREDIENTS IN BF-B BASIC SOLUTION PER 1 LITER SODIUM BICARBONATE------84.0 G. PURIFIED WATER---------1.000 LITERS

10. BF-A CONCENTRATED ACID SOLUTION AND BF-B CONCENTRATED BASIC SOLUTION FOR HEMODIALYSIS ARE PRODUCED BY BIRUNIFARM USING MODERN TECHNIQUES EUROPEAN EQUIPMENT IS USED IN PRODUCTION WATER FOR CONCENTRATES PASSES THROUGH A MULTI-STAGE FILTRATION SYSTEM WITH REVERSED OSMOSIS AND ENTERS THE MIXING TANK, WHERE IS SATURATED WITH SPECIFIC CHEMICAL ELEMENTS, AND PREPARED THE PRODUCTION IS CERTIFIED AND HAS THE INTERNATIONAL CERTIFICATE ISO 13485:2003. Advantages

11. BF-CART POWDER (650 G./720 G.) IS USED IN HEMODIALYSIS APPARATUSES FOR DIALYSIS SOLUTION SATURATED WITH AN APPROPRIATE BF- A CONCENTRATED ACIDIC SOLUTION. IT IS USED FOR THE ACID-ALKALI AND WATER- ELECTROLYTIC BALANCE IN HEMODIALYSIS TREATMENT, TREATMENT OF PATIENTS SUFFERING FROM CHRONIC AND ACUTE RENAL FAILURE, HYPERTENSION, INTOXICATION BF-Cart - Bicarbonate Cartridge for Hemodialysis

12. Equipment and Materials FILLING EQUIPMENT FOR CONCENTRATED SOLUTIONS CLOSING DEVICE

13. INJECTION MOLDING MACHINE SODIUM BICARBONATE FILLING MACHINE Equipment and Materials

14. THANK YOU FOR ATTENTION!