1. DOWN SYNDROME WILL LOHR, AUSTIN WILLIAMS, BRANDON LOPEZ, PAIGE STRICKLAND

2. WHAT IS DOWN SYNDROME? DOWN SYNDROME IS A CONGENITAL DISORDER ARISING FROM A CHROMOSOME DEFECT DOWN SYNDROME IS A CONGENITAL DISORDER ARISING FROM A CHROMOSOME DEFECT DOWN SYNDROME GOT ITS NAME FROM A BRITISH DOCTOR, JOHN LANGDON DOWN DOWN SYNDROME GOT ITS NAME FROM A BRITISH DOCTOR, JOHN LANGDON DOWN DOWN SYNDROME WAS DISCOVERED IN THE YEAR 1959 DOWN SYNDROME WAS DISCOVERED IN THE YEAR 1959 IT WAS DISCOVERED IN BRITAIN IT WAS DISCOVERED IN BRITAIN IT WAS DISCOVERED BECAUSE JOHN LANGDON OBSERVED THE SYMPTOMS AND OUTCOMES OF THE DISEASE IT WAS DISCOVERED BECAUSE JOHN LANGDON OBSERVED THE SYMPTOMS AND OUTCOMES OF THE DISEASE ALTERNATE NAME IS TRISOMY 21 OR TRISOMY G ALTERNATE NAME IS TRISOMY 21 OR TRISOMY G

3. WHAT KIND OF GENETIC DISORDER DOWN SYNDROME A GENETIC CHROMOSOME DISORDER CAUSING DEVELOPMENTAL DELAYS DOWN SYNDROME A GENETIC CHROMOSOME DISORDER CAUSING DEVELOPMENTAL DELAYS IT ARISES FROM A DEFECT INVOLVING CHROMOSOME 21, USUALLY AN EXTRA COPY IT ARISES FROM A DEFECT INVOLVING CHROMOSOME 21, USUALLY AN EXTRA COPY DOWN SYNDROME IS NOT INHERITED, IT OCCURS AS A RANDOM EVENT DOWN SYNDROME IS NOT INHERITED, IT OCCURS AS A RANDOM EVENT

4. Chromosome genetic graphic

5. SYMPTOMS OF DISORDER DECREASED OR POOR MUSCLE TONED DECREASED OR POOR MUSCLE TONED FLATTENED FACIAL PROFILE AND NOSE FLATTENED FACIAL PROFILE AND NOSE SMALL HEAD, EARS AND MOUTH SMALL HEAD, EARS AND MOUTH UPWARD SLANTING EYES UPWARD SLANTING EYES

6. EFFECTS OF DISORDER WEAK MUSCLES WEAK MUSCLES CAN’T TALK PROPERLY CAN’T TALK PROPERLY HEARING PROBLEMS HEARING PROBLEMS DEVELOPMENTAL DELAYS DEVELOPMENTAL DELAYS IMMUNE SYSTEM PROBLEMS IMMUNE SYSTEM PROBLEMS

7. DIAGNOSTICS OF DOWN SYNDROME FLAT FACIAL FEATURES FLAT FACIAL FEATURES SMALL NOSE SMALL NOSE ENLARGED TONGUE (TENDS TO STICK OUT) ENLARGED TONGUE (TENDS TO STICK OUT) HEART DEFECTS WHEN BORN HEART DEFECTS WHEN BORN 200,000 CASES PER YEAR IN THE U.S. 200,000 CASES PER YEAR IN THE U.S. SCREENING TESTS SCREENING TESTS

8. PROGNOSIS OF INDIVIDUAL WITH DISORDER THE AVERAGE LIFESPAN OF A PERSON WITH DOWN SYNDROME IS 60 YEARS OF AGE THE AVERAGE LIFESPAN OF A PERSON WITH DOWN SYNDROME IS 60 YEARS OF AGE THE AGE A PERSON WITH DOWN SYNDROME WILL DEPEND ON THE AGE A PERSON WITH DOWN SYNDROME WILL DEPEND ON SEVERITY OF HEALTH PROBLEMS. A CHILD WITH DOWN SYNDROME WILL AFFECT FAMILY MEMBERS BECAUSE THE INDIVIDUAL WITH DOWN SYNDROME WILL NEED MORE CARE AND HELP WITH CERTAIN THINGS THE STRESS LEVEL WASN’T ANY DIFFERENT IN FAMILIES WITH DOWN SYNDROME

9. TREATMENTS/MEDICATIONS FOR AN INDIVIDUAL WITH DOWN SYNDROME PHYSICAL THERAPY, SPEECH LANGUAGE THERAPY, OCCUPATIONAL THERAPY, EMOTIONAL AND BEHAVIOR THERAPIES PHYSICAL THERAPY, SPEECH LANGUAGE THERAPY, OCCUPATIONAL THERAPY, EMOTIONAL AND BEHAVIOR THERAPIES MEDICATIONS ARE INDICATED ONLY FOR TREATMENT OF PAIN MEDICATIONS ARE INDICATED ONLY FOR TREATMENT OF PAIN

10. CURRENT RESEARCH THERE ARE INJECTIONS FOR DOWN SYNDROME THERE ARE INJECTIONS FOR DOWN SYNDROME THE DOES CANT BE SAFELY USED IN PEOPLE THE DOES CANT BE SAFELY USED IN PEOPLE MOST MOST FREQUENT CHROMOSOMAL CAUSE OF MILD TO MODERATE INTELLECTUAL DISABILITY PEOPLE WITH DOWN SYNDROME ARE AT A GREATER RISK FOR OTHER DISORDERS LIKE HEARING LOSS, PEOPLE WITH DOWN SYNDROME ARE AT A GREATER RISK FOR OTHER DISORDERS LIKE HEARING LOSS, LEUKEMIA, AND

12. SUMMARY A BOY NAMED TED KREMER WAS BORN WITH DOWN SYNDROME. THE DOCTORS TOLD HIS PARENTS THAT HE WOULDN’T LIVE A NORMAL LIFE BECAUSE HE WOULDN’T WALK OR TALK. TED’S PARENTS TOOK AND HOME AND RAISED HIM TO BE A STRONG, RESPECTFUL BOY. HE BECAME A CINCINNATI REDS BASEBALL FAN AND EVERYONE HAD THE PLEASURE OF MEETING HIM.

13. SOURCES HTTP://WWW.WEBMD.COM/CHILDREN/UNDERSTANDING-DOWN-SYNDROME-SYMPTOMS HTTP://WWW.WEBMD.COM/CHILDREN/UNDERSTANDING-DOWN-SYNDROME-SYMPTOMS HTTP://WWW.WEBMD.COM/CHILDREN/UNDERSTANDING-DOWN-SYNDROME-SYMPTOMS WWW.GLOBALDOWNSYNDROME.ORG/ABOUT-DOWN-SYNDROME/FACTS-ABOUT-DOWN- SYNDROME/ WWW.GLOBALDOWNSYNDROME.ORG/ABOUT-DOWN-SYNDROME/FACTS-ABOUT-DOWN- SYNDROME/ WWW.GLOBALDOWNSYNDROME.ORG/ABOUT-DOWN-SYNDROME/FACTS-ABOUT-DOWN- SYNDROME/ WWW.GLOBALDOWNSYNDROME.ORG/ABOUT-DOWN-SYNDROME/FACTS-ABOUT-DOWN- SYNDROME/ DSREASEARCH.STANFORD.EDU DSREASEARCH.STANFORD.EDU HTTPS://WWW.NICHD.NIH.GOV/HEALTH/TOPICS/DOWN/RESEARCHINFO/PAGES/ACTIVITIES. ASPX HTTPS://WWW.NICHD.NIH.GOV/HEALTH/TOPICS/DOWN/RESEARCHINFO/PAGES/ACTIVITIES. ASPX HTTPS://WWW.NICHD.NIH.GOV/HEALTH/TOPICS/DOWN/RESEARCHINFO/PAGES/ACTIVITIES. ASPX HTTPS://WWW.NICHD.NIH.GOV/HEALTH/TOPICS/DOWN/RESEARCHINFO/PAGES/ACTIVITIES. ASPX CHIEN-KUANG DING DUKE STUDENT INTERVIEW