1. © Copyright 2003 Frost & Sullivan. All Rights Reserved. Advances in Biotechnology for the Manufacture of Chemicals: Part 1 Improving Commodity and Specialty Chemical Production Technology Analyst Team Technical Insights “The demand for commodity chemicals, particularly the fuel additive ethanol that the government is promoting by means of tax breaks, and specialty chemicals such as pharmaceuticals, are driving the development of advanced biotechnologies.”

2. © Copyright 2003 Frost & Sullivan. All Rights Reserved. Key Features Technical Insights Provides: Detailed coverage of key developments and trends Analyst insights on ‘hot topics’ and emerging applications in different sectors Discussions on the technology status Detailed list of pertinent patents along with abstracts Profiles of key developers in the field, and contact information

3. © Copyright 2003 Frost & Sullivan. All Rights Reserved. What We Offer Coverage: World Proven methodology based on extensive primary and secondary data and research Focused information and strategies on business and technology issues Credible research and analysis highlighting industry dynamics Contact information for leading technology developers

4. © Copyright 2003 Frost & Sullivan. All Rights Reserved. Who Will Benefit? Current Technology Participants Find out how you compare with the competition Assess current and future trends Determine and exploit new applications and opportunities Find the best candidates for licensing agreements and partnerships New Entrants Analyze the associated challenges Calculate timescales for strategy implementation Position yourself to capitalize on the emerging applications Uncover the best players to assist you with further developing your technology Investment Community Analyze long-term strategies of the market Identify participants that will lead the market development Assess the attractiveness of investing in the market

5. © Copyright 2003 Frost & Sullivan. All Rights Reserved. Key Market Participants Advanced BioNutrition Corp. The University of Akron University of Alberta Bioengineering Resources, Inc. California Institute of Technology University of California, Berkeley University of California, Riverside Center for Advanced Research in Biotechnology Codexis, Inc. Cornell University Diversa Corp. Environmental Biotechnology Institute (EBI) Genomatica, Inc. University of Georgia Government College, Lahore, Pakistan Helsinki University of Technology Igene Biotechnology, Inc. Indian Institute of Technology Institute of Biotechnology, Swiss Federal Institute of Technology Iowa State University James Cook University Kobe University Large Scale Biology Corp. Martek Biosciences Corp.

6. © Copyright 2003 Frost & Sullivan. All Rights Reserved. Key Market Participants (Cont’d) Massachusetts Institute of Technology Maxygen, Inc. Michigan State University Ohio State University Ohio University College of Osteopathic Medicine Pacific Northwest National Laboratory Purdue University Regional Research Laboratory Rice University Southern Illinois University University of St Andrews University of Texas Universidad de Murcia Universidade Federal do Rio Grande do Sul USDA/ARS, Eastern Regional Research Center USDA-ARS USDA-ARS Commodity Utilization Research Unit, Southern Regional Research Center Vertec BioSolvents, Inc. Virent Energy Systems, LLC Wacker-Chemie GmbH Washington State University University of Wisconsin

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