1. CAE 1.2 Andrew Pople University of Pittsburgh 7/19/2006

2. Agenda CAE Overview CAE 1.2 Future Plans

3. CAE Approach To address issues of effort, expense, lack of access -- Provide (semi-)automated electronic import of data from core clinical systems To address issue of different data models and representations -- Transform the source data to a caBIG-standard model

4. CAE Concept AP LISCP LISRegistryCTMAEMR CAE Real Information caTIES caTISSUE Core

5. Example Users Researcher who queries system to find relevant specimens for research Tissue banker who manages operations in the bank and assists other users Pathology Assistant who abstracts surgical pathology reports Pathologist who reviews annotations/adds specialist knowledge Registrar who acquires and documents information about patient treatments and outcomes

6. CAE 1.0 Implements: Basic query Manual annotation XML import of: Patient demographics Anatomic pathology annotations for: Breast Prostate Melanoma

7. CAE 1.2 – New Software Features Enhanced Query Inequalities, ranges, multi-select Simple query page – includes most common elements Export query results or case list to CSV Service API

8. CAE 1.2 – New Models Core elements for: CNS Colorectal Pancreas Kidney Lung

9. CAE – Other Requirements Additional software and modeling to support: Disease Treatment Outcome Dynamic presentation of annotation sets & attributes based on selected values

10. CAE Future – Other Ideas Disease sites Deepen existing Add more Annotations Clinical pathology Specimen types Functionality Richer, more expressive queries Enhanced data integration support More flexible workflow Agility Local extensions Enhanced meta-data Expansion across multiple dimensions:

11. Questions/Comments Thank you!