1. Innovative Solutions in Healthcare

2. Worldwide, 2000 clients, over 800 high quality products A decade of expertise in the field of angiogenesis Innovative and natural solutions to health concerns Cutting-edge purification and ultrafiltration technology Preservative free, patented manufacturing process, excluding the use of chemicals, enzymes or heat Highest quality standards, pharmaceutical grade manufacturing facilities

3. A name that says it all Comitis is the ethymological root of the words companion, concomitant, commitment The product is positioned as an adjuvant to conventional treatments

4. The New Generation of Marine Liquid Cartilage Extract Helps maintain a healthy angiogenesis balance* Helps maintain healthy hematocrit level and red blood cell count* The most active product in the CarTCell line

5. Inhibition of endothelial cell proliferation Inhibition of blood vessel formation Inhibition of VEGF binding and signaling Induction of endothelial cell apoptosis Inhibition of matrix metalloproteinase (MMP) activity Maintenance of a healthy angiogenic balance Bioavailability demonstrated in humans Support of healthy blood parameters in humans Multiple Action Molecular Complex

6. Maintaining healthy cells* Promoting skin health* Supporting joint fonction* Providing macular support, retinal nerve protection, healthy ocular lens function* Healthy aging* Supporting quality of life and energy level* Applications include

7. Water-soluble signaling factors having a molecular weight of less than 500kDa Manufactured at low temperature and kept frozen until use to preserve structure and functional properties Formulated for oral use and available in two different sizes: 30ml and 60ml Aqueous extract easily absorbed with no unpleasant taste or odour Outstanding safety profile Product Description

8. Dosage should be discussed with a healthcare practitioner For higher capacity angiogenesis balance support, we suggest 60ml for a minimum of 4 months For maintenance, 30ml a day, as long as needed Comitris™ should be taken on an empty stomach Comitris™ should remain frozen until consumption Suggested Use

9. Manufacturing and Production Process Raw material certified by fishing centers as being consistent with HACCP standards Sharks are not solely harvested for their cartilage ensuring that shark populations are not endangered The cartilage is mechanically cleaned, shipped frozen to the manufacturing facility and processed under the highest quality requirements

10. Shark cartilage powder: obtained from shark cartilage that has been washed, soaked in water and then dried up and ground. The washing and the soaking steps remove the water soluble signaling factors contained in Comitris™ Comitris™ is preservative free and undergoes a patented manufacturing process excluding the use of chemicals, enzymes or heat Comitris™ is a collection of various physiologically active signaling factors Comitris™ is protected under the following patents: US-05985839, US-05618925, US-06028118, US-06025334, US-06380366, US-20030013858, US-20040081703, US-20020146462, WO-09532722, WO-09716197, WO-00004910 and WO-96123512. versus Shark Cartilage Powder: A Very Significant Difference

11. Product Fact Sheet

12. Key points New product presented as a complement to traditional medecine - First line treatment - In combination with other treatments The most powerful generation of liquid cartilage offered 30% more anti-mmp activity than CTC reg 20% more anti-mmp activity than CTC plus 30 New educational material available online