1. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Arterial and venous network consist of 85 arteries and 158 veins: (a) the arterial system, (b) the venous system, and (c) RCL lumped model studied using the electrical analogy Figure Legend:

2. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Simulated hemodynamics for the heart for both the NVA and EVA male 25 yrs, which consists of four cardiac chambers. RA: right atrium, RV: right ventricle, LA: left atrium, and LV: left ventricle. (a) and (b) show the blood pressure in the heart chambers, pulmonary artery, and ascending aorta; (c) and (d) show the volume in the heart chambers. Figure Legend:

3. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparisons between the simulated data and the measured data of central systolic pressure for both the NVA and EVA Figure Legend:

4. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparison between the simulated and the measured data for both the NVA and the EVA: (a) the central pulse pressure and (b) the central AIx Figure Legend:

5. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Mean blood flow in the selected veins: computational results versus literature data Figure Legend:

6. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Arterial pressure propagation along the arterial tree during one cardiac cycle Figure Legend:

7. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparison of the total flow rate entering the CoW between the simulated NVA, EVA, and the measured data Figure Legend:

8. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparison of the flow rate waveform between the simulated NVA, EVA, and measured waveform in four arterial sites as the large black dot indicates in the arterial tree. (a) the flow rate in the middle cerebral artery, (b) the flow rate in the VA, (c) the flow rate in the ICA, and (d) the flow rate in the CCA. Figure Legend:

9. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparisons of the pressure and flow rate waveform in a complete CoW. Top two waveforms represent the pressure and flow rate in the ACOM artery; bottom two waveforms represent the pressure and flow rate in the PCOM artery. Figure Legend:

10. Date of download: 6/2/2016 Copyright © ASME. All rights reserved. From: The Influence of Normal and Early Vascular Aging on Hemodynamic Characteristics in Cardio- and Cerebrovascular Systems J Biomech Eng. 2016;138(6):061002-061002-10. doi:10.1115/1.4033179 Comparisons of the pressure and flow rate waveform in an incomplete CoW. Top two waveforms represent the pressure and flow rate in the ACOM artery with missing RA1; bottom two waveforms represent the pressure and flow rate in the PCOM artery with missing RP1. Figure Legend: