1. Prevention of HIV Transmission Treatment as Prevention or Behavior Change Interventions? Moderator Victoria A Cargill, M.D., M.S.C.E. Office of AIDS Research, NIH

2. Challenges Scope of the Epidemic

3. Global Estimate of those living with HIV 2012

5. Challenges Awareness of HIV Status

7. Challenges Not Engaging in Care

8. The “Gardner Cascade” Gardner E, et al. CID 2011:52 (Mar 15) 75% 50% 80% 75% 80% 79% o

9. Summary Global pandemic Mature epidemic Those unaware of their HIV status account for over half of the new transmissions Those in care reflect only a small portion of those living with infection How to interrupt the ongoing cycle of disease transmission?