1. SEDATIVE HYPNOTIC

2. USES  Short-term use (days to a few weeks) for insomnia; not for long term use  Long-term use (months or years); long-term use can cause drug- induced abnormalities in the patient's sleep cycle  Antidotes for overdoses of stimulants  Personal story**  In combination with analgesics in painful situations  Preoperative anesthetics  Dental work, surgery, etc.

3. BENZODIAZEPINES  Flurazepam (Dalmane) Schedule IV  Alprazolam (Xanax), Schedule IV  Lorazepam (Ativan), Schedule IV  Diazepam (Valium), Schedule IV  Temazepam (Restoril), Schedule IV  Triazolam (Halcion), Schedule IV  Clonazepam (Klonopin), Schedule IV  Chlordiazepoxide (Librium), Schedule IV

4. PRESCRIBERS ARE MORE LIKELY TO PRESCRIBE A LEGEND DRUG BEFORE A CONTROLLED SUBSTANCE LIKE BENZOS.

5. MISC. DRUGS SIMILAR TO BENZOS  Z Drugs are a group of nonbenzodiazepine drugs with effects similar to benzodiazepines which are used in the treatment of insomnia and whose names mostly start with the letter “Z”.  Some “Z” drugs may have advantages over benzodiazepines:  Zolpidem (Ambien), Schedule IV  Eszopiclone (Lunesta), Schedule IV  Zaleplon (Sonata), Schedule IV  Ramelteon (Rozerem), Legend Drug, is a melatonin receptor agonist-mimics the action of melatonin

6. SIDE EFFECTS  Drowsiness  Addiction  Tolerance and dependence  Respiratory and cardiac depression (with high doses)

7. SKELETAL MUSCLE RELAXANTS

8. USES  Relieve muscle spasm associated with muscle inflammation and injury  Useful in neuromuscular disorders such as Multiple Sclerosis and Cerebral Palsy

9. EXAMPLES  Cyclobenzaprine (Flexeril), Legend Drug  Methocarbamol (Robaxin), Legend Drug  Baclofen (Lioresal), Legend Drug  Chlorzoxazone (Parafon Forte), Legend Drug  Carisoprodol (Soma), Schedule IV  Metaxalone (Skelaxin), Legend Drug  Tizanidine (Zanaflex), Legend Drug  Orphenadrine (Norflex), Legend Drug

10. SIDE EFFECTS  Drowsiness  Addiction  Tolerance and dependence  Respiratory and cardiac depression (with high doses)