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Convergent transcriptional specializations in the brains of humans and song-learning birds by Andreas R. Pfenning, Erina Hara, Osceola Whitney, Miriam.

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Presentation on theme: "Convergent transcriptional specializations in the brains of humans and song-learning birds by Andreas R. Pfenning, Erina Hara, Osceola Whitney, Miriam."— Presentation transcript:

1 Convergent transcriptional specializations in the brains of humans and song-learning birds by Andreas R. Pfenning, Erina Hara, Osceola Whitney, Miriam V. Rivas, Rui Wang, Petra L. Roulhac, Jason T. Howard, Morgan Wirthlin, Peter V. Lovell, Ganeshkumar Ganapathy, Jacquelyn Mountcastle, M. Arthur Moseley, J. Will Thompson, Erik J. Soderblom, Atsushi Iriki, Masaki Kato, M. Thomas P. Gilbert, Guojie Zhang, Trygve Bakken, Angie Bongaarts, Amy Bernard, Ed Lein, Claudio V. Mello, Alexander J. Hartemink, and Erich D. Jarvis Science Volume 346(6215):1256846 December 12, 2014 Published by AAAS

2 Fig. 1 Comparative brain relationships, connectivity, and cell types among vocal learners and nonlearners. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

3 Fig. 2 Optimal alignment of human and zebra finch brain hierarchies. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

4 Fig. 3 Relative number of genes with significantly shared specialized expression between avian and human brain regions. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

5 Fig. 4 Overlap of regions with convergent specialized expression and speech activation. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

6 Fig. 5 Heat map of gene expression specialization in avian RA analogs versus the arcopallium and human LMC/dLSC regions versus other cortical regions. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

7 Fig. 6 Convergent differential regulation of SLIT1 in the RA analog and human LMC. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS

8 Fig. 7 In situ hybridization localization of the putative dLMC/dLSC in the human brain. Andreas R. Pfenning et al. Science 2014;346:1256846 Published by AAAS


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