1. ClearWay™ RX Therapeutic Perfusion Catheter

2. ClearWay™ RX In Action Potential Advantages of ClearWay TM: Delivers drug at high concentration to site of thrombus Prolongs the “Residence Time” of the drug (drug stays in contact with thrombotic lesion longer before being washed away) Provides better penetration of clot with drug Potential Advantages of ClearWay TM: Delivers drug at high concentration to site of thrombus Prolongs the “Residence Time” of the drug (drug stays in contact with thrombotic lesion longer before being washed away) Provides better penetration of clot with drug

3. ClearWay™ RX Indication for Use The ClearWay RX is indicated for localized perfusion of various diagnostic and therapeutic agents into the coronary and peripheral vasculature. It is not indicated for use in the neurovasculature.

4. Occlusion –Occlusion of the lumen during inflation of the atraumatic ClearWay RX balloon allows for maximized drug penetration without dilution by blood flow. Compression –Compression of thrombus at the treatment site improves permeability of drug into the target zone. Infusion –Infusion throughout the entire length of the balloon provides localized delivery of the drug for enhanced therapeutic effect. Occlusion –Occlusion of the lumen during inflation of the atraumatic ClearWay RX balloon allows for maximized drug penetration without dilution by blood flow. Compression –Compression of thrombus at the treatment site improves permeability of drug into the target zone. Infusion –Infusion throughout the entire length of the balloon provides localized delivery of the drug for enhanced therapeutic effect. OCI Therapeutics Occlusion ● Compression ● Infusion

5. ClearWay RX Therapeutic Perfusion Catheter 134 cm Catheter Working Length.014” Guidewire Compatible 6 & 7Fr Guide Catheter Compatible 4 & 5Fr Introducer Sheath Compatible 1-4atm Infusion Pressure 5-7ml/min Infusion Rate 134 cm Catheter Working Length.014” Guidewire Compatible 6 & 7Fr Guide Catheter Compatible 4 & 5Fr Introducer Sheath Compatible 1-4atm Infusion Pressure 5-7ml/min Infusion Rate

6. ClearWay RX Sizes Balloon Diameters 1.0mm* 1.5mm* 2.0mm* 2.5mm* 3.0mm* 3.5mm 4.0mm Balloon Diameters 1.0mm* 1.5mm* 2.0mm* 2.5mm* 3.0mm* 3.5mm 4.0mm Balloon Lengths 10mm 15mm 20mm* 30mm 40mm 50mm * Sizes Currently Available

7. amacord GmbH www.amacord.at amacord GmbH www.amacord.at ClearWay™ RX Therapeutic Perfusion Catheter