1. Searching EMBASE Alex Denby Regional MI Manager London Medicines Information Service (Northwick Park Hospital)

2. Session aims To understand the concepts of a basic search strategy in Embase To describe the EMTREE thesaurus in detail so that you will be able to apply EMTREE to use Embase efficiently To carry out advanced Embase searches

3. Plan What is Embase? (precourse material) Medline v Embase (precourse material) EMTREE NLH Software – searching tools Worked Examples

4. Searching EMBASE Controlled vocabulary = EMTREE Uses natural language US spellings rather than British INNs used where possible Acronyms & abbreviations can be used Tree Structure – Hierarchy Indexing: Terms added/Drug names

5. Open Internet and type: http://www.evidence.nhs.uk/default.aspx http://www.evidence.nhs.uk/default.aspx Select ‘Specialist resources’ / ‘Search Specialist Databases’ Enter Athens password Click on “Healthcare Database Advanced Search” and select Embase NLH Software

6. Embase 1974 to date 2 options to search for terms:  Thesaurus mapping  Browse headings

8. Explode  Includes everything below in the tree structure.  ‘exp’ is put before keyword in results Major description (Focus)  Only includes articles where the MeSH heading (descriptor) is the main focus of the article  ‘  ’ is put before keyword in results Explode/Major descriptor

10. Many more subheading options for drugs compared with Medline e.g. diclofenac By choosing ‘Select’, all subheadings for the term will be chosen without either Exploding or Majoring on the term. Subheadings

12. No real need to use them in EMBASE Most medicines have EMTREE terms – even recently licensed ones If a drug hasn’t got an EMTREE term assigned – use free text CAS numbers

13. Limit searches in similar way to Medline Differences compared with Medline Limits

14. Publication types have their own facet / tree top of EMTREE terms that are searchable Facet J: types of article or study Build up your search and combine in the usual way (using BOOLEAN) with other search terms Publication types

16. Worked example 1 Are there any papers specifically about the use of linezolid for the treatment of MRSA? (Workshop question 1)

18. Worked example 2 Are there any review articles about inhaler use in asthmatic children under 4? (Workshop question 2)

20. Worked example 3 Is there any evidence that minocycline is more effective than any of the other tetracyclines that are licensed for the treatment of acne (tetracycline, lymecycline, oxytetracycline, doxycycline)? (Workshop question 5)

22. Any questions?