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Hippisley-Cox J, Coupland C. Heart 2010;96:939-47.

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Presentation on theme: "Hippisley-Cox J, Coupland C. Heart 2010;96:939-47."— Presentation transcript:

1 Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

2 Baseline characteristics of new users of statins and non-users of statins aged 30-84 years in the QResearch derivation and THIN validation cohorts Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

3 Adjusted HRs (95% CI) for moderate to severe myopathy Models also adjusted for age and body mass index Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

4 Validation statistics for each model in the THIN and QResearch validation cohorts Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

5 Adjusted HRs (95% CI) for acute renal failure Models also adjusted for age and body mass index Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

6 Adjusted HR (95% CI) for moderate/serious liver dysfunction Models also adjusted for age and body mass index Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

7 Adjusted HR (95% CI) for cataract Models also adjusted for age and body mass index Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

8 Predicted to observed risk of each outcome using the QResearch database Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

9 Numbers needed to harm (NNH) or numbers needed to treat (NNT) and numbers of extra or prevented cases, for each outcome over 5 years in patients aged 35-74 free of cardiovascular disease at baseline with QRISK2 score of 20%+ Hippisley-Cox J, Coupland C. Heart 2010;96:939-47


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