Critical Biological Determinants of Incorporation of Non- Vascularized Cortical Bone Grafts. Quantification of a Complex Process and Structure*† by SHARON.

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Presentation transcript:

Critical Biological Determinants of Incorporation of Non- Vascularized Cortical Bone Grafts. Quantification of a Complex Process and Structure*† by SHARON STEVENSON, XIAO QING LI, DWIGHT T. DAVY, LEROY KLEIN, and VICTOR M. GOLDBERG J Bone Joint Surg Am Volume 79(1):1-16 January 1, 1997 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 1 Graph of the mean total area of bone (and standard error) for each group plotted for each time-point. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 2 Graph of the mean area of new bone (and standard error) for each group plotted for each time-point. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 3 Graph of the mean number of vessels (and standard error) in the original graft for each group plotted for each time-point. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Figs. 4-A and 4-B: One hundred-micrometer-thick unembedded cross sections of a fresh syngeneic graft, viewed under epifluorescent illumination (original magnification, x 4). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 4-B At four months, the fresh syngeneic grafts were large, well integrated admixtures of revascularized original graft (G) and lamellar new bone (N). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Figs. 5-A and 5-B: One hundred-micrometer-thick unembedded cross sections of a frozen syngeneic graft, viewed under epifluorescent illumination (original magnification, x 4). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 5-B Small amounts of lamellar new bone (N) were well integrated with the original graft (G) at four months. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Figs. 6-A, 6-B, and 6-C: One hundred-micrometer-thick unembedded cross sections of a fresh allograft with a minor mismatch, viewed under epifluorescent illumination (original magnification, x 4). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 6-B Large amounts of new woven bone (N) were present around the original graft (G) at two months. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 6-C Multiple vascular channels (arrows) had appeared in the original graft by four months. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Figs. 7-A and 7-B: One hundred-micrometer-thick unembedded cross sections of a fresh allograft with a major mismatch at four months, viewed under epifluorescent illumination (original magnification, x 4). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 7-B Almost all of the original cortical graft (G) had been resorbed. SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 8 One hundred-micrometer-thick unembedded cross section of a frozen allograft with a major mismatch at four months, viewed under epifluorescent illumination (original magnification, x 4). SHARON STEVENSON et al. J Bone Joint Surg Am 1997;79:1-16 ©1997 by The Journal of Bone and Joint Surgery, Inc.