Role of the Polycomb Repressive Complex 2 in Acute Promyelocytic Leukemia Raffaella Villa, Diego Pasini, Arantxa Gutierrez, Lluis Morey, Manuela Occhionorelli,

Slides:

Advertisements

Similar presentations

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.

Advertisements

Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation Silvia Di Agostino,

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Lysyl Oxidase-like 2 Deaminates Lysine 4 in Histone H3 Nicolás Herranz, Natàlia Dave, Alba Millanes-Romero, Lluis Morey, Víctor M. Díaz, Víctor Lórenz-Fonfría,

Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence Carmen Guerra, Manuel Collado, Carolina Navas,

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression María J. Bueno, Ignacio Pérez de Castro, Marta Gómez de.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence Shoichiro Takeishi, Akinobu Matsumoto, Ichiro Onoyama, Kazuhito Naka, Atsushi.

Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia Bin Zhang, Yin Wei Ho, Qin Huang, Takahiro Maeda,

C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells Roger R. Gomis, Claudio Alarcón, Cristina Nadal, Catherine.

Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics Carlos L. Arteaga, Jeffrey A. Engelman Cancer Cell Volume.

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Tim C.P. Somervaille, Michael L. Cleary Cancer Cell.

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.

The Microbiome and Cancer: Is the ‘Oncobiome’ Mirage Real? Ryan M. Thomas, Christian Jobin Trends in Cancer Volume 1, Issue 1, Pages (September 2015)

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity Cai-Hong.

Modeling Inducible Human Tissue Neoplasia Identifies an Extracellular Matrix Interaction Network Involved in Cancer Progression Jason A. Reuter, Susana.

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung Zvi Granot, Erik Henke, Elizabeth A. Comen, Tari A. King, Larry Norton, Robert Benezra.

Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.

A Conditional Mouse Model for Malignant Mesothelioma Johan Jongsma, Erwin van Montfort, Marc Vooijs, John Zevenhoven, Paul Krimpenfort, Martin van der.

A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin Malay Haldar, Jeffrey D. Hancock, Cheryl M. Coffin, Stephen L. Lessnick,

Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy James V. Alvarez, Tien-chi Pan, Jason Ruth,

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

T-ALL: Home Is where the CXCL12 Is

Building better therapy for children with acute lymphoblastic leukemia

We Contain Multitudes: The Protean Face of Retinoblastoma

Linking miRNA Regulation to BCR-ABL Expression: The Next Dimension

Volume 1, Issue 1, Pages (June 2007)

The Ids Have It Cancer Cell

Andrew G. Muntean, Jay L. Hess Cancer Cell

CALming Down T Cell Acute Leukemia

A Sweet New Role for EGFR in Cancer

MDS Is a Stem Cell Disorder After All

DAISY: Picking Synthetic Lethals from Cancer Genomes

Volume 26, Issue 1, Pages 1-2 (July 2014)

Eun-Jung Jung, George A. Calin Cancer Cell

Alyson A. Lokken, Nancy J. Zeleznik-Le Cancer Cell

Polycomb Regulates NF-κB Signaling in Cancer through miRNA

A Radical Role for p38 MAPK in Tumor Initiation

CALming Down T Cell Acute Leukemia

Volume 11, Issue 6, Pages (June 2007)

Copyright © 2012, Elsevier Inc. All rights Reserved.

Karin Johanna Ferrari, Elisa Lavarone, Diego Pasini Molecular Cell

Volume 20, Issue 1, Pages 3-5 (July 2011)

Volume 11, Issue 6, Pages (June 2007)

Breaking News on Fragile Sites in Cancer

To Infinium, and Beyond! Cancer Cell

Volume 10, Issue 3, Pages (September 2006)

There's a Time and a Place for MYCN

New Myc-anisms for DNA Replication and Tumorigenesis?

Volume 12, Issue 6, Pages (December 2007)

The Role of TET2 in Hematologic Neoplasms

Presentation transcript:

Role of the Polycomb Repressive Complex 2 in Acute Promyelocytic Leukemia Raffaella Villa, Diego Pasini, Arantxa Gutierrez, Lluis Morey, Manuela Occhionorelli, Emmanuelle Viré, Josep F. Nomdedeu, Thomas Jenuwein, Pier Giuseppe Pelicci, Saverio Minucci, Francois Fuks, Kristian Helin, Luciano Di Croce Cancer Cell Volume 11, Issue 6, Pages (June 2007) DOI: /j.ccr Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 1 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 2 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 3 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 4 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 5 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 6 Cancer Cell , DOI: ( /j.ccr ) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions