Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB) López-Cortés LE.

Slides:

Advertisements

Similar presentations

Prevention of Sepsis Among Neonates Admitted to Intensive Care Units through Promotion of Infection Control Safe Injection Global Network Meeting in Cambodia,

Advertisements

Survival benefits and policy conflicts in Sepsis

Carl Hinkson, MS, RRT-ACCS, NPS, FAARC Respiratory Care Department

Delay from Testing HIV Positive until First HIV Care for Drug Users: Adverse Consequences and Possible Solutions Barbara J Turner MD, MSEd* John Fleishman.

CMS Core Measures Evidence-Based Performance Measurement.

ICS in COPD – A Risk Factor for CAP? Rate of pneumonia in ICS Studies

2.11 Conduct Medication Management University Medical Center Health System Lubbock, TX Jason Mills, PharmD, RPh Assistant Director of Pharmacy.

The long-term outcome after acute renal failure Presented by Ri 顏玎安.

80 (7.3%) patients who were initially admitted to either a general bay or to the TB cohorting bay AND were eventually transferred to the other one during.

1 25th ECCMID , Munich, Germany Magnitude of bacteremia predicts one-year mortality Kim O. Gradel 1, Henrik C. Schønheyder 1,2, Mette Søgaard 1,

C-1 Staphylococcus aureus Bacteremia and Endocarditis: A Bad Bug and A New Drug G. Ralph Corey M.D. Professor of Internal Medicine and Infectious Diseases.

C-Reactive Protein: a Prognosis Factor for Septic Patients Systematic Review and Meta-analysis Introduction to Medicine – 1 st Semester Class 4, First.

Culture Conversion and Self- Administered Therapy in Privately Managed Tuberculosis Patients Melissa Ehman MPH, Jennifer Flood MD MPH, Pennan Barry MD.

Clinical Impact of Adherence to Pharmacotherapeutic Guidelines on the Outcome in Patients with Chronic Heart Failure Suntheep Batra, M.Pharm Department.

1 Is Managed Care Superior to Traditional Fee-For-Service among HIV-Infected Beneficiaries of Medicaid? David Zingmond, MD, PhD UCLA Division of General.

PREDICTING AKI IS MORE CHALLENGING AS AGE PROGRESSES Sandra Kane-Gill, PharmD, MSc Associate Professor, School of Pharmacy.

Complete Recovery of Renal Function After Acute Kidney Injury is Associated with Long-Term All-Cause Mortality In a Large Managed Care Organization Jennifer.

Cognitive Impairment: An Independent Predictor of Excess Mortality SACHS, CARTER, HOLTZ, ET AL. ANN INTERN MED, SEP, 2011;155: ZACHARY LAPAQUETTE.

Deborah Wingard, W. Susan Cheng, Donna Kritz-Silverstein, Elizabeth Barrett-Connor Sensitivity and Specificity of Death Certificates for Diabetes: As Good.

Washington D.C., USA, JULY Rulin C. Hechter 1 MD,PhD Jean Q. Wang 1 PhD Margo A. Sidell 1 ScD William J. Towner 2 MD 1 Dept.

Value of rapid antigen detection tests (RADTs) for diagnosis of invasive group A Streptococci (GAS) 3-centre, retrospective study: N=192 miscellaneous.

Comparison of the Systemic Inflammatory Response Syndrome between Monomicrobial and Polymicrobial Pseudomonas aeruginosa Nosocomial Bloodstream Infections.

Inappropriate empirical antimicrobial Tx for coagulase-negative staphylococcal (CoNS) bacteraemia: impact on survival Single-centre retrospective cohort.

Antibacterial Drugs and the Risk of Community-Associated Methicillin-Resistant Staphylococcus aureus in Children Schneider-Lindner V, Quach C, Hanley JA,

Incidence of hospitalisations in both groups Incidence of documented infections Abstract Problem statement: Patients on cancer chemotherapy are at substantial.

Impact of early surgery vs conventional treatment for infective endocarditis on mortality and embolic events: data from EASE trial Prospective RCT ( );

Systematic review + meta-analysis: 69 (quasi-)randomised trials: N=7,863 pts with sepsis: any BL monoTx vs any combination of BL + AG: N (studies) : same.

Respiratory CONNECT meeting Dr Julius Cairn. Risk stratification in PE Clinical parameters – shock, JVP, S3 Imaging – CTPA, echo Biomarkers – Troponin,

QUALI RISULTATI VORRESTI E QUALI HAI Journal Club ‘Sopravvivere alla Sepsi: i primi 5 anni’ 2 dicembre 2010.

Risk assessment for VTE Dr Roopen Arya King’s College Hospital.

Clinical predictors of adverse outcome in VTE outpatients – the VERITY PUSH (Prospective Follow-Up Survey in Verity Hospitals) study Peter Rose, Aidan.

Higher Incidence of Venous Thromboembolism (VTE) in the Outpatient versus Inpatient Setting Among Patients with Cancer in the United States Khorana A et.

Group A streptococcal (GAS) pharyngitis: food-borne outbreak

Indiaclen Short course of Amoxicillin in treatment of Pneumonia (ISCAP) 3 versus 5 days amoxicillin for treatment of non-severe pneumonia in young children:

Lateral flow device (LFD) test on bronchoalveolar lavage (BAL) samples for diagnosing invasive pulmonary aspergillosis (IPA): diagnostic accuracy Single-centre.

Copenhagen University Hospital Rigshospitalet, Denmark

First Author: Ráduly Kinga Author: Ráduly Orsolya Coordinators: Dr. Zaharia Kézdi Iringo, Dr. Nina Sincu.

Sub module 3 Pre-ART and ART registers. Purpose of registers Key individual information for: Facilitating patient management by the identification of.

Are well infants with urinary tract infections at risk of bacteraemia? Elspeth Ferguson ST6 Paediatrics.

Curtin University is a trademark of Curtin University of Technology CRICOS Provider Code 00301J Gill Lewin, Janine Alan, Helman Alfonso Long Term Outcomes.

Predictors of Failure in Timely TB Treatment Completion, United States Carla Winston,PhD TB PEN Focal Point Open Forum June 5,

Aspects of HIV in Denmark Jane Agergaard, MD, PhD Department of Infectious Diseases Aarhus University Hospital Skejby Denmark.

How clinicians use data to make an impact on clinical outcomes Andrew Brodbelt Consultant Neurosurgeon and Clinical Director of Neurosurgery, The Walton.

Ross T. Tsuyuki, BSc(Pharm), PharmD, MSc, FCSHP, FACC Yazid NJ Al Hamarneh, BPharm, PhD Charlotte Jones, MD, PhD, FRCP(C) Brenda Hemmelgarn, MD, PhD, FRCP(C)

Diabetes and Obesity Journal Club Carina Signori Endocrinology Fellow

< 회기-강동 합동 컨퍼런스> Systemic Inflammatory Response Syndrome criteria in Defining Severe sepsis Kirsi-Maija Kaukonen, M.D., Ph.D., Michael Bailey, Ph.D.,

The Risks of Thromboembolism Vs. Recurrent Gastrointestinal Bleeding after Interruption of Systemic Anticoagulation in Hospitalized Inpatients With Gastrointestinal.

MRSA on Ward 29 University Hospital Aintree (UHA) April 2006-August 2010 Zoe Greenwood February 2011.

JUST GIVE IT: a 2 phase study to audit the Immediate Management of Patients with Proven or Suspected Neutropenic Sepsis by Ally Gruber Acute Oncology Clinical.

Acute Renal Failure in HIV- Infected Individuals Greatly Increases Risk for In-Hospital Mortality Slideset on: Wyatt CM, Arons RR, Klotman PE, Klotman.

Predicting Mortality in Non-Variceal Upper Gastrointestinal Bleeders: Validation of the Italian PNED Score and Prospective Comparison With the Rockall.

Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult ICU patients Crit Care Med 2007 ; 35 :

Harm from Invasive Devices Dr. Eleri Davies, Faculty Lead HCAI.

Is it possible to predict New Onset Diabetes After Transplantation (NODAT) in renal recipients using epidemiological data alone? Background NODAT is an.

Timing of Post-discharge Venous Thromboembolic Events and Effect of Pharmacologic Prophylaxis in Hospitalized Patients Paul J. Grant MD, Todd Greene PhD,

JAMA Internal Medicine May 2015 Volume 175, Number5 R1 조한샘 / Prof. 이창균.

F. 정 회 훈 Am J Gastroenterol 2012;107:46-52 Risk of Hepatocellular Carcinoma in Diabetic Patients and Risk Reduction Associated With Anti-Diabetic Therapy:

Time for first antibiotic dose is not predictive for the early clinical failure of moderate–severe community-acquired pneumonia Eur J Clin Microbial Infect.

VALDEZ ET AL CLINICAL INFECTIOUS DISEASES 2011;52(6):726–735 R2 Kim Dong Hyun Decreased Infection-Related Mortality & Improved Survival in Severe Aplastic.

An AKI project for critically ill cancer patients

－ Higher SBP visit-to-visit variability (SBV) has been associated

An Automated, Pharmacist-Driven Initiative Improves Quality of Care for Staphylococcus aureus Bacteremia Eric Wenzler1, Fei Wang2, Debra Goff2, Beth Prier2,

Copyright © 2014 American Medical Association. All rights reserved.

Neonatal sepsis in Kilifi

Trends in Overall and Cause-Specific Mortality Among Patients With Inflammatory Bowel Disease From 1982 to 2010 Tine Jess, Morten Frisch, Jacob Simonsen

Baseline C-reactive protein level as a predictor of mortality in bacteraemia patients: a population-based cohort study K.O. Gradel, R.W. Thomsen, S.

Increasing incidence but decreasing in-hospital mortality of adult Staphylococcus aureus bacteraemia between 1981 and 2000 T. Benfield, F. Espersen,

Sequential time to positivity of blood cultures can be a predictor of prognosis of patients with persistent Staphylococcus aureus bacteraemia M.-S. Hsu,

Correlation between time to positivity of blood cultures with clinical presentation and outcomes in patients with Klebsiella pneumoniae bacteraemia: prospective.

Lecture 4 Study design and bias in screening and diagnostic tests

Presentation transcript:

Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB) López-Cortés LE. ECCMID 2013 abs. O119 Multi-centre, before-after-study: N=462 pts with Staphylococcus aureus bacteraemia (SAB) (excluding palliative care or death within first 72h of SAB) from 11 Spanish tertiary hospitals CIB: Active consulting and follow-up of all SAB episodes by infectious disease specialist who provided written structured recommendations ≥3 days/week related to quality of care indicators Outcome parameters: Management (quality of care) and outcome (mortality) of SAB + 6 months Clinical intervention bundle (CIB) based on 5 evidence-based quality of care indicators 1 of 2

Quality of care Mortality Mortality during 6-month period: PRE: 27.6% vs INT: 23.6%; P=0.3 Multivariable logistic regression (adjusted for age, Pitt score, type of acquisition, development of severe sepsis/septic shock ) : CIB is independent predictor of lower mortality: OR=0.46; 95% CI: ; P=0.02 Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB) Application of a CIB for management of SAB may improve adherence to 3 quality of care indicators and decrease in-hospital mortality López-Cortés LE. ECCMID 2013 abs. O119 2 of 2

Outbreak of Elizabethkingia meningoseptica sepsis with meningitis in a well baby nursery Case report: N=3 newborns developing multi-resistant E. meningoseptica (Chryseobacterium meningosepticum) sepsis with meningitis in a well baby nursery (Taiwan; March-May 2012) Chen YJ. ECCMID 2013 abs. P957 1 of 2 Data from poster FU: follow-up; VP: ventriculoperitoneal

Outbreak of Elizabethkingia meningoseptica sepsis with meningitis in a well baby nursery An outbreak of E. meningoseptica sepsis and meningitis in a well baby nursery was possibly transmitted via contaminated facilities and was controlled after changing and sterilising them Chen YJ. ECCMID 2013 abs. P957 Intervention: Plastic storage boxes, cleaned with tap water without sterilisation → replaced by stainless steel boxes with regular desinfection 2x/week → no more E. meningoseptica infections since then 2 of 2 Data from poster

Risk of venous thromboembolism (VTE) after community-acquired bacteraemia (CAB) Population-based cohort study (Northern Denmark; ): –Study group: N=4,237 adult pts with CAB, confirmed by blood cultures on admission to medical ward (exclusion criteria: no recent hospital admission, no previous CAB or VTE) –Control group: 10 non-hospitalised controls for each CAB patient, matched for age, sex and date of admission Dalager-Pedersen M. ECCMID 2013 abs. O287 1 of 2

Risk of venous thromboembolism (VTE) after community-acquired bacteraemia (CAB) CAB is associated with an increased risk of first-time VTE 3 months and 1 year after diagnosis. However, the absolute risk of hospital- diagnosed VTE after CAB is low Dalager-Pedersen M. ECCMID 2013 abs. O day risk of VTE after CAB according to organism: Highest for Staphylococcus aureus: 3.62% Adjusted relative risk (RR) for VTE after CAB: 2 of 2