Box 3A The Voltage Clamp Technique

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Presentation transcript:

Box 3A The Voltage Clamp Technique neuro4e-box-03-a-0.jpg

Box 3A The Voltage Clamp Technique neuro4e-box-03-a-0r.jpg

Figure 3.1 Current flow across a squid axon membrane during a voltage clamp experiment neuro4e-fig-03-01-0.jpg

Figure 3.1 Current flow across a squid axon membrane during a voltage clamp experiment (Part 1) neuro4e-fig-03-01-1r.jpg

Figure 3.1 Current flow across a squid axon membrane during a voltage clamp experiment (Part 2) neuro4e-fig-03-01-2r.jpg

Figure 3.2 Current produced by membrane depolarizations to several different potentials neuro4e-fig-03-02-0.jpg

Figure 3.2 Current produced by membrane depolarizations to several different potentials (Part 1) neuro4e-fig-03-02-1r.jpg

Figure 3.2 Current produced by membrane depolarizations to several different potentials (Part 2) neuro4e-fig-03-02-2r.jpg

Figure 3.3 Relationship between current amplitude and membrane potential neuro4e-fig-03-03-0.jpg

Figure 3.4 Dependence of the early inward current on sodium neuro4e-fig-03-04-0.jpg

Figure 3.5 Pharmacological separation of Na+ and K+ currents neuro4e-fig-03-05-0.jpg

Figure 3.6 Membrane conductance changes underlying the action potential are time- and voltage-dependent neuro4e-fig-03-06-0.jpg

Figure 3.6 Membrane conductance changes underlying the action potential are time- and voltage-dependent (Part 1) neuro4e-fig-03-06-1r.jpg

Figure 3.6 Membrane conductance changes underlying the action potential are time- and voltage-dependent (Part 2) neuro4e-fig-03-06-2r.jpg

Figure 3.6 Membrane conductance changes underlying the action potential are time- and voltage-dependent (Part 3) neuro4e-fig-03-06-3r.jpg

Figure 3.6 Membrane conductance changes underlying the action potential are time- and voltage-dependent (Part 4) neuro4e-fig-03-06-4r.jpg

Figure 3.7 Depolarization increases Na+ and K+ conductances of the squid giant axon neuro4e-fig-03-07-0.jpg

Figure 3.8 Mathematical reconstruction of the action potential neuro4e-fig-03-08-0.jpg

Figure 3.8 Mathematical reconstruction of the action potential (Part 1) neuro4e-fig-03-08-1r.jpg

Figure 3.8 Mathematical reconstruction of the action potential (Part 2) neuro4e-fig-03-08-2r.jpg

Figure 3.8 Mathematical reconstruction of the action potential (Part 3) neuro4e-fig-03-08-3r.jpg

Figure 3.9 Feedback cycles responsible for membrane potential changes during an action potential neuro4e-fig-03-09-0.jpg

Box 3B Threshold neuro4e-box-03-b-0.jpg

Figure 3.10 Passive current flow in an axon neuro4e-fig-03-10-0.jpg

Figure 3.10 Passive current flow in an axon (Part 1) neuro4e-fig-03-10-1r.jpg

Figure 3.10 Passive current flow in an axon (Part 2) neuro4e-fig-03-10-2r.jpg

Box 3C(1) Passive Membrane Properties neuro4e-box-03-c(1)-0.jpg

Box 3C(2) Passive Membrane Properties neuro4e-box-03-c(2)-0.jpg

Figure 3.11 Propagation of an action potential neuro4e-fig-03-11-0.jpg

Figure 3.12 Action potential conduction requires both active and passive current flow neuro4e-fig-03-12-0.jpg

Figure 3.12 Action potential conduction requires both active and passive current flow (Part 1) neuro4e-fig-03-12-1r.jpg

Figure 3.12 Action potential conduction requires both active and passive current flow (Part 2) neuro4e-fig-03-12-2r.jpg

Figure 3.13 Saltatory action potential conduction along a myelinated axon neuro4e-fig-03-13-0.jpg

Figure 3.13 Saltatory action potential conduction along a myelinated axon (Part 1) neuro4e-fig-03-13-1r.jpg

Figure 3.13 Saltatory action potential conduction along a myelinated axon (Part 2) neuro4e-fig-03-13-2r.jpg

Figure 3.13 Saltatory action potential conduction along a myelinated axon (Part 3) neuro4e-fig-03-13-3r.jpg

Figure 3.14 Speed of action potential conduction in unmyelinated versus myelinated axons neuro4e-fig-03-14-0.jpg

Figure 3.14 Speed of action potential conduction in unmyelinated versus myelinated axons (Part 1) neuro4e-fig-03-14-1r.jpg

Figure 3.14 Speed of action potential conduction in unmyelinated versus myelinated axons (Part 2) neuro4e-fig-03-14-2r.jpg

Figure 3.14 Speed of action potential conduction in unmyelinated versus myelinated axons (Part 3) neuro4e-fig-03-14-3r.jpg