Genetics Shireen Rudina. First: A review of Mendel’s Laws 1.Dominance 2.Law of Segregation- one allele from each parent 3.Law of Independent Assortment-

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Presentation transcript:

Genetics Shireen Rudina

First: A review of Mendel’s Laws 1.Dominance 2.Law of Segregation- one allele from each parent 3.Law of Independent Assortment- each trait acts independently

Human Mendelian Traits GENETIC TRAITDOMINANTRECESSIVE

How about the rest? 1.Multiple alleles: blood type IAIA Type A blood IBIB Type B blood iType O blood IAIAIAIA Type A I a iType A IBIBIBIB Type B I B iType B IAIBIAIB Type AB iiType O blood Codominance

Question: A mother is Type A, and her child is type O 1.What is the child’s and mother’s phenotype? 2.There are two men claiming to be the father: one is Type B, and the other is Type AB. Which one is the father?

How about the rest? 2. Multiple genes for one trait

Sex Chromosomes: X and Y

Pedigree Method of following a trait down generations

Analyzing Pedigrees

Tay-Sachs Disease: Simple genetic trait

Tay-Sachs: A recessive disease Nervous system and brain rapidly deteriorate Children generally die by age 4 Carriers are crucial

If daughter A marries someone with the trait, what is the probability that their child will be affected? ? A

Replication

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Semiconservative Replication