Nicotine Delays Tendon-to-Bone Healing in a Rat Shoulder Model by L.M. Galatz, M.J. Silva, S.Y. Rothermich, M.A. Zaegel, N. Havlioglu, and S. Thomopoulos.

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Presentation transcript:

Nicotine Delays Tendon-to-Bone Healing in a Rat Shoulder Model by L.M. Galatz, M.J. Silva, S.Y. Rothermich, M.A. Zaegel, N. Havlioglu, and S. Thomopoulos J Bone Joint Surg Am Volume 88(9): September 1, 2006 ©2006 by The Journal of Bone and Joint Surgery, Inc.

Photomicrographs demonstrating increased cell proliferation in the saline solution group as compared with the nicotine group at twenty-eight days (magnification, ×40). L.M. Galatz et al. J Bone Joint Surg Am 2006;88: ©2006 by The Journal of Bone and Joint Surgery, Inc.

Photomicrographs demonstrating increased type-I collagen expression (evident as black grains) in the saline solution group as compared with the nicotine group at twenty-eight days (magnification, ×20). L.M. Galatz et al. J Bone Joint Surg Am 2006;88: ©2006 by The Journal of Bone and Joint Surgery, Inc.

Graphs depicting the biomechanical findings in the two groups. L.M. Galatz et al. J Bone Joint Surg Am 2006;88: ©2006 by The Journal of Bone and Joint Surgery, Inc.