Stein Lab In-House Symposium 2002

Lincoln Sends His Regrets

International HapMap Project  Find regions of linkage disequilibrium in human population.  Reduce cost of genetic association studies.  Understand human population history. Gudmundur Thorisson Fiona Cunningham Ardavan Kanani

WormBase  Community database for C. elegans  C. elegans genome  C. briggsae genome  Genetic maps  Developmental anatomy  RNAi screens  Microarray screens  Evolutionary biology Jack Chen Todd Harris

Genome KnowledgeBase  Biological pathways in human  Curated by experts in the field  Designed for  Education  Data mining & discovery  Open data/Open software Geeta Joshi-Tope Peter D’Eustachio Gopal Gopinathrao Guanming Wu Marc Gillespie Lisa Matthews

Generic Model Organism Db Scott Cain Shulamit Avraham  Reusable software for building model organism databases  Used by WormBase, FlyBase, Gramene, RatDB, SGD, MGD…  Genome browsers, genetic maps, curation tools… Shuly Avraham Scott Cain Ken Clark

Gramene  Comparative genomics among monocots  Rice as model system  Rice genome, maps, proteins, mutants, QTLs, phenotypes  Map alignments to maize, wheat, oats, barley &c. Doreen Ware Chris Mahr Liya RenKiran Kumar Steve Schmidt Chris Mahr Wei Zhao