THE IMMUNE SYSTEM LECTURER: DAVID.

Slides:



Advertisements
Similar presentations
Humoral Immunity Ajith Sominanda Department of Anatomy.
Advertisements

ANTIGEN-ANTIBODY INTERACTION LECTURER: DAVID. OBJECTIVES.
Today’s Agenda w Objective notes w Practice w Objective notes.
IMMUNITY.
HUMORAL AND CELL-MEDIATED IMMUNITY
Humoral Immunity.
Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 67 Review of the Immune System.
1 Immunology: Specific Immunity Immunity: not being susceptible to disease Types of immunity –Innate: you have it from birth. Species: as humans, immune.
Adaptive immunity How can the immune system recognize so many different (previously unseen) insults? How does the immune system learn? How do B cells produce.
Humoral Immunity and Complement Robert Beatty MCB150.
Adaptive immunity How can the immune system recognize so many different (previously unseen) insults? How does the immune system learn? How do B cells produce.
Microbiology B.E Pruitt & Jane J. Stein AN INTRODUCTION EIGHTH EDITION TORTORA FUNKE CASE Chapter 17, part A Specific Defenses of the Host: The Immune.
General Microbiology (Micr300)
Specific Immune Defense. Antigens Antibody-generator, Non-self, Large molecules Properties: ◦1. Immunogenicity ◦2. Reactivity Antigenic determinant or.
Lecture 3 Antibody-Antigen Reactions
The Immune System. Immune System Our immune system is made up of: The innate immune system: first line of defence (non-specific) The adaptive immune system:
u Proteins that recognize and bind to a particular antigen with very high specificity. u Made in response to exposure to the antigen. u Each antibody.
Blood Types Ch Blood Types Blood cells have surface markers called antigens ABO Blood Group – RBC with A antigens – A blood type – RBC with B antigens.
Adaptive Immunity  Response occurs within days of the infection  Highly specific  Highly diverse  Memory component  Major cell types involved: T cells,
IMMUNOLOGY Immunoglobulin.
Immunity Innate and Adaptive Immunity Cells of the Immune System
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chapter 14 Specific Immunity (adaptive immunity)
Specific Defense Mechanisms – The Immune System
Ch.16. What is Immunity?  Immunity is resistance to infection after a foreign antigen has penetrated the first line of defense,  Immunity is achieved.
Lecture 14 Immunology: Adaptive Immunity. Principles of Immunity Naturally Acquired Immunity- happens through normal events Artificially Acquired Immunity-
Humoral Immunity Antibodies.
Komal Choudhary Lecturer School of Biotechnology DAVV Indore.
Humoral Immunity presented by Dr. MAHROO MIRAHMADIAN Professor of Immunology Tehran University of Medical Sciences.
Copyright © 2010 Pearson Education, Inc. Antibodies Immunoglobulins—gamma globulin portion of blood Proteins secreted by plasma cells Capable of binding.
Imunoglobulins – structure and function Production of immunoglobulins Genetic determination of immunoglobulin production Clonal selection theory.
Dental Microbiology #211 IMMUNOLOGY 2006 Lecture 4 The Antibodies and the Complement System.
Defense &The Immune System Overview. Immune System Agenda The bigger picture Non specific defenses Specific defenses (Immunity)
Principle of Single Antigen Specificity Each B cell contains two copies of the Ig locus (Maternal and Paternal copies) Only one is allowed to successfully.
The Immune System 2 1. Adaptive Specific immunity (acquired) = the ability of the body to defend itself against specific invading agents such as bacteria,
Humoral Immune Response Terry Kotrla, MS, MT(ASCP)BB Fall 2006.
Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.
HUMORAL IMMUNITY Primary molecular component: antibody
Highlights of Immune System. Topic Outline Overview of the Immune System 1 st and 2 nd lines of Defense The Immune System  B cells  The antibody & antibody.
The Adaptive Immune Response
Heavy Chains – Isotypic Differences
IMMUNOLOGY OF ABO AND RH BLOOD TYPES. EACH BLOOD TYPE IS NAMED ACCORDING TO THE ANTIGENS ON ITS SURFACE.
Specific Immune Responses How the Immune System Handles Specific Antigens.
ANTIBODIES def - protein molecules that combine specifically with antigens. Proteins with antibody activity are known as immunoglobins.
Antibody CLS-415 Nada Mohamed Ahmed, MSc, MT (ASCP)i.
___________DEFENSES of the HOST: THE IMMUNE RESPONSE
8 th lecture The collaborations between innate and adaptive immunity. Antibody types and functions.
Chapter 17 Immune response. Two types of resistance. Innate resistance and acquired resistance. Innate resistance – one is born with the resistance. All.
Lector Tvorko M. S.. ANTIBODIES (IMMUNOGLOBULINS) Antibodies are globulin proteins (immunoglobulins) that react specifically with the antigen that stim­ulated.
COLLABORATION OF INNATE AND ADAPTIVE IMMUNITY ANTIBODY STRUCTURE AND FUNCTION 8 th week Physiotherapy BSc 2015.
Red Blood Cells  Surface has “Markers” called Antigens.
ANTIBODIES. Cells cooperation in immune response.
Antigens Immunogen – a molecule that specifically interacts with an antibody or lymphocyte and elicits an immune response Antigenic determinants (epitopes)
Chapter 15:Adaptive Immune Response. General Characteristics Involves specialized WBC’s known as lymphocytes Response is highly specific, evolves throughout.
Antibodies Heroes of the humoral response 1/25/11 Lab #3 Adaptive immunity.
Lecture 14 Antibody-Antigen Reactions. Binding of the epitope in the antigen binding site POOR FIT GOOD FIT antibody combining site antigen determinant.
Do Now 3/26/15 1.How are nonspecific defenses different than specific defenses? 2.How does a fever help protect the body from pathogens? 3.Which types.
Kidney.
The Adaptive Immune Response
Effector mechanisms of humoral immunity
Antibodies (Immunoglobulin)
Defense &The Immune System
Antibodies (Immunoglobulins)
Antibodies: Structure And Function
Chapter 17 Immune response.
Antibodies.
Specific Defenses of the Host: The Immune Response
The Antibody.
Humoral Immunity.
Lecture 14 Antibody-Antigen Reactions
Immunology Immunity Specificity Memory Tolerance.
Presentation transcript:

THE IMMUNE SYSTEM LECTURER: DAVID

ANTIGEN-ANTIBODY INTERACTIONS

INNATE VERSUS ADAPTIVE RESPONSE INNATEADAPTIVE

ANTIBODY!

ANTIBODY STRUCTURE

WHAT IS AN ANTIBODY??

BUT WHAT IS AN ANTIGEN???

SUMMARY

ANTIBODY FUNCTIONS

NEUTRALIZATION

OPSONIZATION

PHAGOCYTOSIS

COMPLEMENT

AGGLUTINATION

ABO BLOOD GROUPS

THERE ARE LOTS OF TYPES OF ANTIBODIES

IgG

IgA

IgM

IgE

IgD

OBJECTIVES

QUESTION Which immunoglobulin can cross the placenta?

ANSWER IgG

QUESTION If you mix a person with type A blood and anti-A antibodies, will agglutination occur?

ANSWER Yes

QUESTION What is the difference between neutralization and opsonization?

ANSWER Neutralization – antibody binds a toxin and makes it harmless Opsonization – antibody binds an antigen and targets it for phagocytosis

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.