INFLAMMATION LECTURE 5 DR HEYAM AWAD. MOROHOLOGY OF ACUTE INFLAMMATION DILATED BLOOD VESSELS. OEDEMA. INFLAMMATORY CELLS.

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Presentation transcript:

INFLAMMATION LECTURE 5 DR HEYAM AWAD

MOROHOLOGY OF ACUTE INFLAMMATION DILATED BLOOD VESSELS. OEDEMA. INFLAMMATORY CELLS.

MORPHOLOGY OF ACUTE INFLAMMATION SEROUS INFLAMMATION. FIBRINOUS INFLAMMATION. SUPPURATIVE INFLAMMATION, ABSCESS. ULCERATION

SEROUS INFLAMMATION CELL- POOR FLUID. CLASSICAL EXAMPLE: SKIN BLISTERS DUE TO BURNS OR VIRAL INFECTION.

SEROUS INFLAMMATION

SEROUS INFLAMMATION.

FIBRINOUS INFLAMMATION INCREASED PERMEABILITY.....EXUDATION OF FLUID AND LARGE MOLECULES SUCH AS FIBRINOGEN. FIBRIN FORMED AND DEPOSITED IN EXTRACELLULAR SPACES.

FIBRIN

SUPPURATIVE INFLAMMATION PUS = NEUTROPHILS, NECROTIC DEBRIS, FLUID. CAUSED BY BACTERIAL INFECTION.

SUPPURATIVE TONSILLITIS

SUPPURATIVE APPENDICITIS

ULCERATION LOCAL DEFECT CAUSED BY SLOUGHING OF NECROTIC TISSUE.

GASTRIC ULCER

OUTCOMES OF ACUTE INFLAMMATION COMPLETE RESOLUTION. HEALING BY CONNECTIVE TISSUE. PROGRESSION TO CHRONIC INFLAMMATION.

COMPLETE RESOLUTION INJURY LIMITED OR SHORT LIVED. LITTLE TISSUE DESTRUCTION. REMOVAL OF CELLULAR DEBRIS AND PATHOGENS BY MACROOGAGES AND RESORPTION OF OEDEMA FLUID BY LYMPHATICS.

HEALING BY CONNECTIVE TISSUE FORMATION SCARRING OR FIBROSIS. HAPPENS AFTER: SIGNIFICANT TISSUE DESTRUCTION TISSURE INCAPABLE OF REGENERATION. ABUNDANT FLUID THAT CANNOT BE CLEARED.

SYSTEMATIC EFFECT OF INFLAMMATION FEVER. CYTOKINES STIMULATE PROSTAGLANDIN PRODUCTION....FEVER. SERUM PROTEINS...CRP, FIBRINOGEN, SERUM AMYLOID A. ACT AS OPSONINS.

SYSTEMIC EFFCTS LEUKOCYTOSIS. CYTOKINES STIMULATE PRODUCTION OF WBCs FROM THEIR PRECURSORS IN BONE MARROW.