This material was developed by Duke University, funded by the Department of Health and Human Services, Office of the National Coordinator for Health Information.

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Presentation transcript:

This material was developed by Duke University, funded by the Department of Health and Human Services, Office of the National Coordinator for Health Information Technology under Award Number IU24OC Component 9 - Networking and Health Information Exchange Unit Supporting Standards for EHR Application

Unit 7-2 Objectives Understand –Standards for clinical guidelines –Object-oriented expression language for clinical decision support GELLO Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Guidelines Computer-interpretable guidelines Sharing computer-interpretable guidelines Guidelines –Deliver patient-specific recommendations –Integrated with EHRs Automated reminders and alerts Decision support and task management Order entry appropriateness, referral criteria Background monitoring, care plans, quality review Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Benefits of Guidelines Provide automatic decision support –Applied to individual patients –Perform retrospective analysis to test if patients were treated appropriately Simulations Aid human visualization –Interactive, dynamic display of guideline pathways –Allows one to focus on relevant sections of flowchart Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Challenges in Sharing Guidelines Local adaptation of guidelines –Availability of resources and expertise –Local workflow issues –Practice preferences Integration with local information systems –Match patient data from EHR to GL –Match recommendations in guideline to actions in order entry systems Dissemination formats Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Common Shared Model Ability to share guideline across –Different platforms and systems –Different guideline models Joint development of: –Shared model that incorporates features of different models –Tools to support entire guideline life cycle Authoring, validation, local adaptation & mappings, execution, revision and update Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Expressiveness Ability to express knowledge content of different types of guidelines –Structured parts Definitions, recommendations, algorithms Decision-support guideline tasks –Expressive decision model –Specifying work to be performed –Data interpretation –Generating alerts and reminders Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Comprehensibility Guideline visualization and readability Complexity management Coherence facilitation –e.g., Support material Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Implementation Requirements Ease of –Guideline integration into clinical environments –Sharing actual specifications Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Integration into Clinical Environment Local adaptation of guideline content Integration with EHR –Mapping references to patient data to entries in EHR –Mapping recommendations to implementable actions e.g. Linking to order entry system Printing a prescription Workflow integration Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Guideline Representation Models Arden Syntax GLIF GEM DILEMMA EON PROforma Asbru GUIDE PRODIGY Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

GuideLine Interchange Format (GLIF) A format for sharing clinical guidelines independent of platforms and systems Based on a object-oriented logical model of concepts Has an XML-based syntax Is an executable model Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

GLIF Model Flowchart representation of a temporal sequence of clinical steps Guideline has title and author Guideline Step –Decision step –Action step –Branch step –Synchronization step –Patient sleep step Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

GLIF Classes Action steps: –Recommendations for clinical actions to be performed Prescribe aspirin Decision steps: –Criteria for conditional flowchart traversal If patient has pain, then (x) Branch and synchronization steps –Allow concurrency Patient-state sleep –Characterizes patient’s clinical state Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Three Representation Levels Author/viewer level –Conceptual flowchart of clinical actions and decisions –Aids in human understanding Abstract machine representation –Can be executed by an interpreter –Correctness can be analyzed Integration into application environments Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Abstract Machine Representation Unambiguous syntax for logical expressions based on Arden Syntax All logical expressions & actions refer to defined concepts –Medical ontology Allowed values, ranges, and time constraints Can be interpreted and analyzed for correctness –Syntax, type, and range checking Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Guideline Elements Model (GEM) Developed at Yale Center for Medical Informatics Hierarchical data structure to organize the heterogeneous information contained in practice guidelines Includes a XML editor specifically for guideline markup called GEM Cutter Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Structure of GEM Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring … …

GELLO Object-oriented expression language for clinical decision support Based on Object Constraint Language Used to –Build up queries to extract and manipulate data from EHRs –Construct decision criteria by building up expressions to reason about particular data features/values such as guidelines –Create expressions, formulae, and queries for applications within other HL7 standards Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Expression Language Used for specifying decision criteria and deriving summary values Provides basic built-in data types, assuming an underlying data model virtual medical record (vMR) that is a refinement of the HL7 RIM Major problem to sharing clinical knowledge is lack of common format for data encoding and manipulation Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Requirements Targeted to clinicians who need to use expression language for sharing and manipulating knowledge in medical context Declarative language Extensible Vendor independent Platform independent Object-oriented and compatible with vMR Easy to read/write Side-effect free (leaves system unchanged) Flexible Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Relationship of GELLO Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring Arden Syntax ( Guidelines) GLIF ( Sequential Knowledge) RIM (Ontology) Other DS & KBs Object-Oriented data modelvMR GELLO Q&E

GELLO Expressions Any text string conforming to the definition of an expression in GELLO language specification –Build decision criteria –Abstract or derive summary values The result of the evaluation of an expression is a value with a specified data type Examples of expressions –calcium.notEmpty() and phosphate.notEmpty() –Renal_failure and calcium_phosphate_product > threshold_for_osteodystrophy Includes temporal operators Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring

Example in GELLO Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring Let month : CodedValue = Factory.CodedValue(""SNOMED-CT", " ") Let finding : CodedValue = Factory.CodedValue("SNOMED-CT", " ") Let azotemia : CodedValue = Factory.CodedValue ("SNOMED-CT", " ") Observation ? exists(code.equal(finding) and value.implies(azotemia) and effective_time.intersect(ThreeMonthsAgo, PointInTime.NOW()))

Summary Component 9/Unit 7-2Health IT Workforce Curriculum Version 2.0/Spring This subunit has discussed guideline representation models. The future of such work is likely to be based on GELLO. Guidelines themselves are very important. Use of guidelines should increase significantly with pressure from Meaningful Use.