Identification of a 3D dosimeter best-suited for use by the RPC M. Heard, G. Ibbott, D. Followill, R. White, E. Jackson, M. Salehpour.

Slides:

Advertisements

Similar presentations

Chapter 4 Radiation Dosimeters

Advertisements

GAFCHROMIC Applications Prince KIRYAMAN ISP

Results/Discussion cont’d. Excluding data past the depth of 10% dose, 91% of points passed. A trend towards over-response was noted in the BANG3-Pro2 dosimeter.

Commissioning an Anthropomorphic Spine and Lung Phantom for Remote Dose Verification of Institutions Participating in RTOG 0631 Douglas Caruthers, M.S.;

Challenges in Credentialing Institutions and Participants in Advanced Technology Clinical Trials Geoffrey Ibbott, David Followill, Andrea Molineu, Jessica.

Texture Analysis for Radiotherapy So-Yeon Park 31 st of Dec, 2013.

Algorithms used in heterogeneous dose calculations show systematic error as measured with the Radiological Physics Center’s anthropomorphic thorax phantom.

Evaluation of the characteristics of TLD LiF:Mg.Ti-100 Powder: A Measure of Consistency Between Multiple Batches of Powder Paola Alvarez,Jose Francisco.

Introduction Radiosensitive polyacrylamide gels (PAG) provide a method of mapping dose distributions in 3D with sub-millimetre resolution [1]. Largely.

Fricke gel dosimeters for the measurement of the anisotropy function of a HDR Ir-192 brachytherapy source Mauro Carrara 1, Stefano Tomatis 1, Giancarlo.

P. Pérez, V. Galván, G. Castellano & M. Valente.  To develop a simple and versatile dosimetric method capable of determining changes in matter (Xylenol.

Lic. Pedro Antonio Pérez.  To develop a simple and versatile dosimetric method capable of determining changes in matter (Xylenol Orange added Fricke.

Optimisation of X-ray micro-tomography to perform low-dose imaging of highly-dosed gels P.M.Jenneson, E.C.Atkinson, P.Wai and S.J.Doran In 1993, Maryanski.

Introduction A Fricke gel was the first dosimetric system to offer the possibility of making 3-D radiation dose measurements in a totally non-destructive.

Introduction Three-dimensional gel dosimetry is a novel method for radiation measurement motivated by the need to verify experimentally the doses produced.

Uni S School of Electronics and Physical Sciences Department of Physics University of Surrey Guildford Surrey GU2 7XH, UK Optimisation of X-ray micro-tomography.

Introduction Spectrophotometry has been the conventional technique for measuring optical density of irradiated gels [1]. Later, magnetic resonance imaging.

Introduction Following Gore’s observation [1] that the well known method of Fricke dosimetry [2] was ideally suited to a “readout” by Nuclear Magnetic.

Introduction The effect of air-cavities within the human body, for example in the head and neck regions, present possible sources of error when calculating.

Innovation/Impact: By designing a simulated human shaped (anthropomorphic) plastic phantom with targets, organs at risk (OAR) and heterogeneities, the.

Dosimetric evaluation of a new design MOSFET detector Per H. Halvorsen* & Stephanie Parker University of North Carolina.

Results The measured-to-predicted dose ratio criteria used by the RPC to credential institutions is , however for this work, a criteria of

11. – , Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl.

S Dr. S. J. Doran Department of Physics, University of Surrey, Guildford, GU2 7XH, UK High-resolution measurements of radiation dose in 3-D using gel dosimetry.

Introduction A modification of the Fricke solution system to make it suitable for low-level dosimetric studies was proposed about three decades ago [1].

Measurement of Dose to Critical Structures Surrounding the Prostate from Intensity-Modulated Radiation Therapy (IMRT) and Three Dimensional Conformal Radiation.

Test of the proposed method Introduction CCD Controller CCD Illuminator gel Filter 585nm Assembling the phantom before its irradiation. The phantom, ready.

Kelly Younge, Ph.DKelly Younge, Ph.D Don Roberts, Benedick Fraass, Daniel McShan, and Martha Matuszak University of Michigan, Department of Radiation Oncology,University.

Evaluation of the Performance of the Fast Scanning Platform of an OCT System Malcolm Heard 1, Miguel Herrera 1, Geoffrey Ibbott 1 1 Department of Radiation.

In vivo dosimetry Eirik Malinen Eva Stabell Bergstrand Dag Rune Olsen.

16 th International Congress on Neutron Capture Therapy June 14-19, 2014 Helsinki, Finland Study of suitability of Fricke-gel-layer dosimeters for in-air.

G. Bartesaghi, 11° ICATPP, Como, 5-9 October 2009 MONTE CARLO SIMULATIONS ON NEUTRON TRANSPORT AND ABSORBED DOSE IN TISSUE-EQUIVALENT PHANTOMS EXPOSED.

Healthcare research in the Physics Department Dr S J Doran Lecturer in Magnetic Resonance Imaging Department of Physics School of Electronics and Physical.

MRI SIMULATION FOR CONFORMAL RADIATION THERAPY OF PROSTATE CANCER Pasquier D 1-3, Palos G 3, Castelain B 1, Lartigau E 1,2, Rousseau J 2,3 1 Department.

Introduction Since 1996 [1], it has been clear that optical computed tomography (CT) represents a viable alternative to MRI scanning of dosimeter gels.

CT physics and instrumentation

The RPC Proton Therapy Approval Process

S Optical CT scanning of PRESAGE TM polyurethane samples with a CCD-based readout system S J Doran 1*, N Krstajic 1, J Adamovics 2 and P M Jenneson 1 1.

Application of a 2-D ionization chamber array for dose verification of dynamic IMRT with a micro-MLC Fujio ARAKI, PhD 1, S. TAJIRI 2, H. TOMINAGA 2, K.

Commissioning of an Optically-Stimulated Luminescence (OSL) system for remote dosimetry audits J.F. Aguirre, P. Alvarez, C. Amador, A. Tailor, D. Followill,

Radiological Physics Center David Followill, Ph.D. and RPC Staff.

Fig. 3 shows how a dose distribution that is initially relatively sharp becomes blurred with time, until after 16 hours, virtually no useful information.

2010 Student Practice in JINR Fields of Research

The Radiological Physics Center’s Anthropomorphic Quality Assurance Phantom Program Carrie F. Amador, Nadia Hernandez, Andrea Molineu, Paola Alvarez, and.

1 A Comprehensive Study on the Heterogeneity Dose Calculation Accuracy in IMRT using an Anthropomorphic Thorax Phantom S Davidson 1, R Popple 2, G Ibbott.

Investigation of 3D Dosimetry for an Anthropomorphic Spine Phantom R. Grant 1,2, G. Ibbott 1, J. Yang 1, J. Adamovics 3, D Followill 1 (1)M.D. Anderson.

AIR CORE SCINTILLATION DOSIMETER SUMMARY We have shown that Cerenkov light can be reduced to a negligible level in scintillation dosimetry by using an.

Development and Implementation of a Remote Audit Tool for High Dose Rate (HDR) 192 Ir Brachytherapy Using Optically Stimulated Luminescence Dosimetry Kevin.

S Scarboro 1,2, D Cody 1,2, D Followill 1,2, P Alvarez 1, M McNitt-Gray 3, D Zhang 3, L Court 1,2, S Kry 1,2 * 1 UT MD Anderson Cancer Center, Houston,

Xoft Routine Per Article Manufacturing Testing of the Axxent ® Source S. Axelrod, T.W. Rusch, M. Powell; Xoft, Inc., Fremont, CA  Purpose: To select sources.

Alexis Dimitriadis Prof Karen Kirkby Prof Andrew Nisbet Dr Catharine Clark Dr Anthony Palmer.

K. Pulliam, MS 1,2., D Followill, PhD 2., L Court, PhD 2., L Dong, PhD 3., M Gillin, PhD 2., K Prado, PhD 3., S Kry, PhD 2 1 The University of Texas Graduate.

Introduction The Radiological Physics Center (RPC) anthropomorphic quality assurance (QA) phantom program is one tool the RPC uses to remotely audit institutions.

Conclusions Despite being able to acquire successfully high resolution images of radiation dose, image quality is limited by hardware problems. Upgrading.

Investigation into the radiochromic (FXG) gel dosimeter: stability and uncertainty in optical measurements M A Bero, S J Doran and W B Gilboy Department.

A Phantom for use in an MR Imager BME 400 October 14, 2005.

TLD POSTAL DOSE QUALITY AUDIT FOR 6MV AND 15MV PHOTON BEAMS IN RADIOTHERAPY CLINICAL PRACTICE Sonja Petkovska 1, Margarita Ginovska 2, Hristina Spasevska.

Purpose N-isopropylacrylamide (NIPAM) polymer gel dosimeters were employed to verify the dose distribution of clinical intensity modulated radiation therapy.

Qing Liang, PhD Medical Physicist Mercy Health System, Janesville, WI

Three-dimensional Dose Verification Using Normoxic Polymer Gel Dosimeters for Tomotherapy Tung-Hsin Wu 1, Chien-Yi Hsiao 2, Mu-Bai Chang 2, Geoffrey Zhang.

1 3rd oPAC Topical Workshop on Beam Diagnostics, CIVIDEC, Vienna, 8th-9th May 2014.

Retroactive Calculation of TLD and Film Dose in Anthropomorphic Phantom as Assessment of Updated TPS Performance H. Alkhatib 1, S. Oves 1, B. Tsang 1,

Characterization of proton-activated implantable markers for proton range verification using PET J. Cho1, G. Ibbott1, M. Kerr1, R. A. Amos2, F. Stingo1,

EURADOS Working Group 9: Radiation Dosimetry in Radiotherapy

Left Posterior Superior Right Anterior Inferior

Development and characterization of the Detectorized Phantom for research in the field of spatial fractionated radiation therapy. D. Ramazanov, V. Pugatch,

A. Nisbet 1,2, A. Dimitriadis 1,2,3, A.L. Palmer 1,4, C.H. Clark 2,3

Chapter 17 Intensity-Modulated Radiation Therapy

Study Identification and Selection Process

Exposed film demonstrating distinct radiation fields on the skin when the C-arm was rotated between 12° LAO and 12° RAO (16 cm field of view (FOV) on Artis.

Presentation transcript:

Identification of a 3D dosimeter best-suited for use by the RPC M. Heard, G. Ibbott, D. Followill, R. White, E. Jackson, M. Salehpour

Motivation RPC has a family of anthropomorphic phantoms Phantoms use TLD and film Radiation treatments are 3D A 3D dosimeter is needed

Which 3D dosimeters? There are many 3D formulations to choose from –BANG ®, MAGIC, MAGAT, PAGAT, VIPAR, PRESAGE™, etc.

Purpose Characterize several different 3D dosimeters and identify one best- suited for the RPC’s needs.

3D Formulations Investigated PAGAT (polymer gel) 1 –manufactured in-house BANGkit™ (polymer gel) 2 –Supplied by MGS Research Inc. PRESAGE™ (radiochromic dosimeter) 3 –Supplied by Heuris Pharma 1 Venning, A.J., et al., Investigation of the PAGAT polymer gel dosimeter using magnetic resonance imaging. Physics in Medicine & Biology, (16): p Murakami, Y., et al., Evaluation of the basic properties of the BANGkit™ gel dosimeter. Phys. Med. Biol., (8): p Adamovics, J. A. and M.J. Maryanksi, Characterisation of PRESAGE™: A new 3-D radiochromic solid polymer dosemeter for ionising radiation. Radiation Protection Dosimetry, 2006.

Polymer Gels –Made of water, gelatin, and monomers –Irradiation initiated polymerization process –Polymers change the optical turbidity and relaxation properties of the gel PRESAGE™ –Composed of a polyurethane matrix doped with leuco dye –Dosimeters are optically clear before irradiation –Irradiation causes exposed areas to turn blue UnirradiatedIrradiated

Determined the dose response up to 10 Gy using 6 MV photons for 3 batches of each formulation Determined the dose resolution and inter- batch reproducibility 2 Gy5 Gy10 Gy PAGAT dosimeters irradiated to different doses

A half-blocked field was used to irradiate a batch of each formulation Doses of 2 Gy, 5 Gy, and 8.25 Gy were delivered –Multiple dosimeters irradiated at each dose level Radiochromic film also irradiated using a half-blocked field Determined the dosimetric accuracy, spatial accuracy, and intra-batch reproducibility

Imaging PRESAGE™ dosimeters imaged with optical CT Polymer gels were imaged with optical CT and MRI Bruker 4.7T scanner Optical CT system

Dose response of PAGAT imaged with OCT. Error bars represent one standard deviation.

Dose resolution of PAGAT imaged with OCT

PRESAGE™ irradiated to 8.25 Gy using a half blocked field

PRESAGE™ irradiated to 2 Gy using a half blocked field

Characteristics Evaluated 1.Dosimetric accuracy 2.Dose resolution 3.Cost 4.Intra-batch reproducibility 5.Monotonic dose response 6.Spatial accuracy 7.Linear dose response 8.Inter-batch reproducibility

Summary Dose response differs by more than 4% between batches of each 3D dosimeter formulation Intra-batch reproducibility > 2% for all dosimetry systems OCT system resulted in inaccuracies at low OD PAGAT polymer gel with OCT imaging was selected as the dosimetry system to be tested in the RPC’s phantoms

Thank You