Regulations. PHS and USDA PHS Policy on Humane Care and Use of Laboratory Animals NIH - OLAW oversees animal welfare for vertebrates Guide for The Care.

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Presentation transcript:

Regulations

PHS and USDA PHS Policy on Humane Care and Use of Laboratory Animals NIH - OLAW oversees animal welfare for vertebrates Guide for The Care and Use of Lab. Animals OLAW Assurance USDA – Animal Welfare Act Regulates warm blooded animals Excludes mice, rats, or birds bred for research

IACUC Institutional Animal Care and Use Committee Self assessment and monitor Volunteer service

IACUC Scientist, non-scientists, veterinarian, public member Oversee and evaluate the entire Program -Protocol review and significant changes -Inspection of facilities and animal use areas -Review the Program -Ongoing assessment of animal care & use -Meeting attendance -Review concerns IO has ultimate responsibility

Protocol Must have IACUC approval to conduct activities. Rational & Purpose of the proposed use of animals Description of the procedures Justification of species and numbers – power analysis Less invasive procedure Unnecessary duplication of experiments

Protocol Nonstandard housing & husbandry requirements Impact of proposed procedures on well being Sedation, analgesia, anesthesia Surgical procedures & multiple procedures Post procedural care & observation Rationale for selected endpoints

Protocol Criteria & process for intervention, removal, or euthanasia Method of euthanasia Personnel training and experience Hazardous materials & safe working environment

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