Proteins Containing Non-natural Amino Acids as Building Blocks for Novel Materials Kristi L. Kiick, University of Delaware, DMR-0239744 Protein and peptides.

Slides:

Advertisements

Similar presentations

1 Amino acid and proteins Ghollam-Reza Moshtaghi-Kashanian Biochemistry Department Medical School Kerman University of Medical sciences.

Advertisements

Bandgap Engineering of UV-Luminescent Nanomaterials Leah Bergman, University of Idaho, DMR CAREER One of the main advantages of a nanomaterial.

Molecularly, collagen exists as a triple helical structure that is stabilized by the presence of the amino acid hydroxyproline. These triple helices further.

National Science Foundation Increasing thermo-electric conversion efficiency by defect engineering Robert F. Klie, University of Illinois at Chicago, DMR.

Design and Deposition of Electroactive Polymers for Light-emitting Diodes and Photovoltaics: DMR Mary Galvin, University of Delaware and Lewis.

How do defects and minor solute control the corrosion properties of solid solution alloys? Investigation of the effects of structural (order – disorder.

National Science Foundation Developing Oxides for Solar Energy Conversion Steven May, Drexel University, DMR Outcome: Researchers at Drexel University.

1. Primary Structure: Polypeptide chain Polypeptide chain Amino acid monomers Peptide linkages Figure 3.6 The Four Levels of Protein Structure.

Bader Al Salman Abstract In this work, we use chemical vapor deposition (CVD) technique to synthesize CdS 1D-nanostructures (nanobelts & Sea-Urchin like.

Stilbene based alternating copolymers exhibit semi-rigid backbones due to the steric crowding of the extra phenyl group (vis-à-vis styrene copolymers)

Materials World Network: Self-assembled Nanocomposite Magnetoelectric Thin Films Nian Sun, Northeastern University, DMR Intellectual Merit:Fig.

Nanocrystallinity Engineering: Tailoring Properties and Functionalities of Metal Nanoparticles Min Ouyang, University of Maryland, DMR

National Science Foundation Material for Future Low-Power Electronics Daniel Gall, Rensselaer Polytechnic Institute, DMR Outcome: Researchers at.

Optoelectronic Supramolecular Block-Copolymer Assemblies Aided by Donor-Acceptor Interactions Alexander Sidorenko, University of the Sciences in Philadelphia,

We have demonstrated several successful outcomes to date: (1) Chemical protocols can be readily implemented for the production of elastomeric polypeptides.

“POLYMER LIGHT EMITTING DIODES (PLEDs) ”

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Linking chemically dissimilar polymer chains.

Charge Photogeneration and Recombination in Organic Semiconductors, Lewis Rothberg, University of Rochester, DMR (with M. Rubner MIT MRSEC, T.

National Science Foundation Dynamic Phenomena in Complex Oxides for Electrochemical Energy Storage Ying S. Meng, University of California-San Diego, DMR.

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Figure 1. (a) Synthesis, (b) transmission electron.

Interfacial Characteristics of Semi fluorinated Polymers Dvora Perahia (Clemson University) DMR Thin layers of semifluorinated and fluorinated.

This EAGER project is aimed at investigating the edge- on chemical gating effect on electronic properties of semiconducting molecules and materials. Three.

“Bottom-Up” Design of Nanostructured Conducting Polymer Thin Films Evgueni E. Nesterov, Louisiana State University & Agricultural and Mechanical College,

One of our recent research efforts focuses on the synthesis of Mg x Zn 1-x O nanoalloys and on studies concerning their optical and material properties.

Switchable Polymer Interfaces for Bottom-up Stimulation of Mammalian Cells Igor Luzinov, Clemson University, DMR The Materials Work Network project.

National Science Foundation Dynamic Phenomena in Complex Oxides for Electrochemical Energy Storage Ying S. Meng, University of California-San Diego, DMR.

High K Films: Organic Field Effect Transistors Using Self Assembled Barium Titanate Nanoparticles Stephen P. O’Brien, Columbia University, DMR

Figure 1. (a) Transmission Electron Micrograph of synthesized FeCo nanoparticles (20nm). (b) X-ray diffraction pattern confirming BCC crystalline structure.

National Science Foundation Enhanced Pyroelectric and Electrocaloric Effects in Complex Oxide Thin Film Heterostructures Lane W. Martin, University of.

Proteins Enzymes are Proteins. Proteins Proteins: a chain of amino acids 20 different amino acids are found in proteins.

This Materials World Network collaborative program brings researchers (Alford and Mayer) from Arizona State University (ASU) and (D. Adams and N. Tile)

ETY tel: fax: Nanoscale physics of nitride semiconductor heterostructures.

National Science Foundation Materials for Optical Properties by Design at the UV Range Leah Bergman, University of Idaho, DMR Outcome: The researchers.

High Anisotropy Magnetic Nanoparticles and Nanocomposites G.C Hadjipanayis, University of Delaware Tel: (302) NSF MET DMR

Nanoscale Science and Engineering. Nanoscale Science and Engineering embodies fundamental research and technology development of materials, structures,

1 um We seek to understand the electrical and optical properties of single organic semiconducting molecules contacted on either end by metal electrodes.

Structure-Function-Property Relationships in Conjugated Polyelectrolytes (CPEs) Thuc-Quyen Nguyen, University of California-Santa Barbara, DMR

100nm c d a b Figure 2. Island shapes (AFM phase images) for different metal-species/Si-orientation combinations: (a) Au/Si(001), (b) Au/Si(111), (c) Sn/Si(110),

The use of polymer layers in light emitting devices has many applications in flexible devices and electronics, and relies on the ability of these polymers.

Understanding of Induced Liquid Crystal Alignment by A Rubbed Polymer Surface Y. Ron Shen, Univ. California, Berkeley DMR H2H2 Polyvinyl cinnamate.

Ferroelectric Nanolithography Extended to Flexible Substrates Dawn A. Bonnell, University of Pennsylvania, DMR Recent advances in materials synthesis.

Negative Capacitance Devices to Enable Low- Voltage/Low-Power Switching In Electronic Devices John G. Ekerdt, University of Texas at Austin, DMR

Materials Integration of III-V Compounds for Electronic Device Applications The funding for this project has provided us with the means to understand the.

National Science Foundation Sb-doped SnO 2 as a transparent contact on InGaN/GaN LEDs James S. Speck, University of California-Santa Barbara, DMR

Switchable Polymer Interfaces for Bottom-up Stimulation of Mammalian Cells Igor Luzinov, Clemson University, DMR The Materials Work Network project.

CAREER: Synthesis, Characterization and Discovery of Frontier Carbon Materials Yoke Khin Yap, Michigan Technological University, DMR The arrangement.

National Science Foundation New Functional Oxides For Electrochemical Energy Storage Ying S. Meng, University of California-San Diego, DMR Outcome:

Exploiting geometry to generate anisotropic interactions at the nanoscale and self-assembly of living clusters Angelo Cacciuto, Columbia University, DMR.

CAREER: Synthesis and Electronic/Electrical Properties of Carbon Nanotube Junctions Wenzhi LiFlorida International UniversityDMR One of the objectives.

Approaches to the fabrication of surfaces that combine methods for the topographic patterning of soft materials with opportunities for facile, post-fabrication.

Thermal Properties of ZrB 2 Ceramics William Fahrenholtz, Missouri University of Science and Technology, DMR % C ZrB 2 + pores 1% C Graphite inclusions.

Award Title: M n+1 AX n Phase Solid Solutions: Unique Opportunities at Engineering Bulk and Surface Properties Michel W. Barsoum, Drexel University, DMR.

Optoelectronic Supramolecular Block-Copolymer Assemblies Aided by Donor- Acceptor Interactions Alexander Sidorenko, University of the Sciences in Philadelphia,

National Science Foundation Novel Graphene-Fullerene Hybrid Materials: Experiment and Theory Krishna Muralidharan, University of Arizona, DMR Outcome:

A Rinse AFM Detection Blue LED Array Photo Irradiation h  Vis) h  Cis Trans Photoisomerization of Azo Dye F-actin solution (1  L) + MgCl 2 Solution.

From quasi-2D metal with ferromagnetic bilayers to Mott insulator with G-type antiferromagnetic order in Ca 3 (Ru 1−x Ti x ) 2 O 7 Zhiqiang Mao, Tulane.

One-pot Synthesis of Dumbbell Polymers through Chain Walking Polymerization Zhibin Guan, University of California - Irvine DMR Figure 1. AFM images.

Advanced Optical Glasses for Novel Optical Fibers Kathleen Richardson, Clemenson University Research Goundation, DMR The international, multidisciplinary.

CAREER: Position-Controlled Doping of Semiconductor Nanocrystals Y. Charles Cao, University of Florida, DMR Doping refers to the process of intentionally.

National Science Foundation Graphene mediated self-assembly of fullerene nanotubes Krishna Muralidharan, University of Arizona, DMR Outcome: Researchers.

National Science Foundation Outcome: Researchers at University of Maryland have created a semiconductor film from the earth abundant elements copper and.

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Linking chemically dissimilar polymer chains.

Spin at the Nanoscale: Material Synthesis and Fundamental Physics Min Ouyang, University of Maryland – College Park, DMR In the FY08, we continued.

ZnO and Mg x Zn 1-x O are technologically promising materials for luminescence applications in the ultraviolet (UV) range. ZnO has a bandgap ~3.3 eV, while.

Ion Transport in Beta-Gallia Rutile Intergrowths Doreen Edwards, Alfred University, DMR Beta-gallia-rutile (BGR) intergrowths possess 1-D tunnels.

Generating Accelerating Light with Metasurfaces

Partnership between NMHU and OSU in Electronic, Optical and Magnetic Materials; DMR One step synthesis of fluorescent graphene quantum dots through.

Fabrication of Nano-porous Templates Using Molecular Self-Assembly of Block Copolymers for the Synthesis of Nanostructures Luke Soule, Jason Tresback Center.

X-ray diffraction spectra during in situ annealing of FCZ glass

Partnership between NMHU and OSU in Electronic, Optical and Magnetic Materials; DMR One step synthesis of fluorescent graphene quantum dots through.

Presentation transcript:

Proteins Containing Non-natural Amino Acids as Building Blocks for Novel Materials Kristi L. Kiick, University of Delaware, DMR Protein and peptides offer many opportunities for the production of advanced materials for nanotechnology applications, as their structure can be exactly controlled and manipulated. The aim of this DMR project is to design and synthesize peptide- and protein-based materials on which the presentation of electroactive moieties can be well controlled (see figure on the right). Exerting this level of control over the placement and interaction of electroactive groups has potential use in the design of flexible light emitting devices for display applications. In this project, we have demonstrated the synthesis of the molecules shown, and have verified their helicity experimentally. Furthermore, the luminescence behavior of the molecules has also been shown to vary controllably as a function of the designed placement and number of the side chains. Specifically, two or three side chains placed close together (a,b) show the most significant interactions, which are reduced upon increasing the distance (c) or orientation (d) of the side chains. Controlling electronic behavior as a function of electroactive group placement offers great potential for the production of advanced electroactive materials. The impact of additional variations in group placement and identity will also be studied in efforts to produce new devices. Light-emitting polymer film ITO (Indium tin oxide) Glass substrate Metal Cathode (Au, Al, Si, Mg) Red – a, b Blue/green – c, d Altering photoluminescence via controlling placement of electroactive groups on peptides. The differences in intensity and spectral shape confirm that the electroactive sidechains are interacting in structures (a) and (b). The novel peptides and proteins produced in this work may serve as light-emitting elements in luminescent devices. Schematics of the helical molecules under investigation in this work; the placement of the groups along the helix controls the electronic properties of the molecules. (a) (b) (c)(d)

The successful outreach program, “The Science of Art”, expanded in late 2004/early 2005 to include the efforts of Prof. Kiick and four graduate students in the MSE department. Students at Haddon Township High School (NJ) were introduced, in two separate sessions held at the high school, to the materials concepts involved in metal working and in ceramics and glaze formulation. The students learned the science behind controlling the properties of the metals used in their artwork, and also produced their own ceramic glazes for desired artistic effects. Proteins Containing Non-natural Amino Acids as Building Blocks for Novel Materials Kristi L. Kiick, University of Delaware, DMR Education: This National Science Foundation funded project continues to stimulate collaboration between biosynthetic and organic synthetic groups at the University of Delaware, and fosters a highly interdisciplinary learning environment, encompassing both biosynthetic methods and electroactive polymer design, for the graduate students currently involved in this project. Additionally, the Kiick laboratories have hosted several undergraduate research students in the laboratories during the summer and semesters, and these students have gained exposure to the use of artificial proteins in materials applications. Outreach: Outreach at the secondary school level continues in two types of activities. First, one high school student has continued to conduct research in the Kiick labs, in the area of polysaccharide-polymer block copolymer synthesis. This student was awarded an honorable mention in the prestigious Davidson Fellowship competition in Outreach program participants Onur Kas, Prof. Kiick, Matt Lamm, Danielle Rockwood, and Tuna Yucel. (a) Kas and Lamm at the high school. (b) Magnified image (200x) of metal oxide surface prepared.