Organ & Tissue Transplants

Slides:

Advertisements

Similar presentations

The Knee Is a Joint More specifically … A LEG JOINT.

Advertisements

Immune system, Organ Transplants and Blood Chapter 13.

Transplantation Immunology1 Transplantation: Chapter 17 You are not responsible for: Immunosuppressive therapies Clinical aspects of specific organ transplants.

Transplantation Autologous Syngeneic Allogeneic Xenogeneic.

Transplantation MCB150 Beatty

Transplantation Rejection of foreign tissue grafts is due to immune responses to alloantigens on the graft Blood group antigens Polymorphic MHC antigens.

Principles of Immunology Transplantation Immunology 4/25/06

Blood Groups Prof. K. Sivapalan. June 2013Blood grouping2 Blood groups. Transfusion reactions indicated different types of blood among individuals. Surface.

Immune System Disorders What is an allergy anyway?

Arrhythmia Treatment …which you researched! Coronary Artery Bypass Surgery Angioplasty Valve Replacement Aneurysm Repair Transplant.

Organ Transplantation. Transplant History Skin grafts – possibly as early as 2 nd century 1 st confirmed skin graft – 16 th century Tissue transplants.

Principles of Transplant Surgery Ruth Mitchell, BA, BSc, BMBS Neurosurgical Resident Royal Melbourne Hospital Thursday, 25 th March 2010.

 A heart on a NC driver’s license indicates you want to be a donor  It is illegal to buy or sell organs and tissues for transplantation in the United.

Table SA-1: Number of Kidney Transplants by Donor Type and Re-Transplant Status Source: Canadian Organ Replacement Register, 2014, CIHI *Missing data for.

Go Recycle Yourself Facts about organ, eye and tissue donation.

ORGAN & TISSUE DONATION Get the Facts. Saving Lives at All Ages.

By Casey Schuler Advanced Physiology Deoxygenated blood enters right atrium from superior and inferior vena cava Blood is pushed into the right.

Living Donor Kidneys in PAK 2/11 USA Primary DD Pancreas Transplants 1/1/1988 – 12/31/2010.

{ KIDNEY TRANSPLANT Kemal VATANSEVER216 Burak YILDIRIM222.

Immune System: Cell-Mediated Immunity & Immune System Disorders 12d.

Chapter 12 ppt 3 The Lymphatic System Disorders

Heart Transplants. How long have heart transplants been performed? 1967 in South Africa.

Scott A. Smolka1 LDS 102, S17 2/7/06 Scott A. Smolka Department of Computer Science Stony Brook University

1 Transplantation therapy for terminal organ failure or tissue damage by transfer of healthy organ or tissue ( graft) donor - the individual who provides.

Transplantation and its use in gene technology by Christopher Schlemm and Ilja Klebanov.

3.7 Organ Transplantation Performed since early 1800’s, 1 st blood transfusions First organ transplant (kidney) 1954 Transplantable organs: heart,liver,lung,pancreas,intestines.

18-1 Important terms: Hypersensitivity – immune responses that causes tissue damage Autoimmune disease – immune responses to self-antigens Immunodeficiency.

Go Recycle Yourself Facts about organ, eye and tissue donation.

HEART DISEASE SBI 3C: DECEMBER HEART ATTACK:  Blood flow to a section of the heart is blocked  If oxygen cannot get through the muscle starts.

Circulatory system cont’d. Hypertension Cause: ◦Chronic high blood pressure (~140/90) ◦Damages heart and blood vessels ◦Can lead to coronary heart disease.

Section 3 Transplant Rejection

TRANSPLANTATION & REJECTION Objectives: Upon the completion of this lecture the students are expected to: Know the benefits of transplantation in clinical.

 In Canada there are 14 organ donors per 1 million people.  In 2007, 4195 Canadians were waiting for organ transplants and of those 193 people died.

Artificial Tissue and Organ Generation Valerie Fortin BME 281.

1.Disease: heart, kidney, liver 2.Trauma 3.Environment: x-rays, 2 nd hand smoke 4. Aging 5.Congenital Defects: cleft palate, heart.

Chapter 16 Lymphatic System and Immunity vessels that assist in circulating fluids transports fluid to the bloodstream transports fats to bloodstream 16-2.

Essentials of Anatomy and Physiology Fifth edition Seeley, Stephens and Tate Slide 2.1 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin.

Medical Treatments for Heart Disease Chapter 17 Section 5 Amy Bentle and Amanda Jones.

Essentials of Human Anatomy & Physiology Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slides – Seventh Edition.

Organ Transplantation

MHC and transplantation MHC & Transplantation 周炫辰邹知耕张顺郑艳宗瑶赵静.

Coronary Heart Disease. Coronary Heart Muscle  Coronary arteries and veins are found within heart muscle  Blood Clots  Coronary thrombosis  Coronary.

The Good, The Bad & The Ugly

 What I Already Knew. What I Already Knew.  My Search Results. My Search Results.  What I Learned. What I Learned.

TRANSPLANTATION & tissue rejection

By Carissa Metzger FACE TRANSPLANTS. WHO CAN RECEIVE A FACE TRANSPLANT? Most face transplants deal with people who have a bone disease or an accident.

Transplantation The following terms are used to denote different

V.IMMUNITY AND CANCER Genetics of Immunity Human Immune System: evolved to keep potentially harmful organisms out of our bodies Pathogens: disease causing.

Lecture 10 Immunology Transplantation Dr. Dalia Galal.

Autoimmune Diseases How Do the Immune Cells of the Body Know What to Attack and What Not To Attack ?

DISEASES OF THE CIRCULATORY SYSTEM Atheroschlerosis Cause: Fatty build up in the arteries due to diet.

Tissue Regeneration How can the blackworm’s special ability apply to humans?

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture Slide Presentation prepared by Christine L. Case M I C R.

Organ Donation & Transplantation EXCI233 Online source: rs/transplantation/overview_of_transplantation.html?qt.

 Transplantation is the process of taking cells, tissues, or organs, called a,graft, from one individual and placing them into a different individual.

AUTOIMMUNE DISEASES 324 PHT Dr. Sarah I. Bukhari PhD in Clinical Microbiology Department of Pharmaceutics Office: rd floor

HOMEOSTASIS The maintenance of a constant internal environment. The main body conditions we have to maintain are: 1.Water content/balance 2.Ion content/balance.

Immune System Disorders Lec. 9. Immunodeficiency Immunodeficiency: any condition in which there is deficiency in the production of humoral and/or cell-

Immune Disorders and Imbalances. Organ Transplants There are 4 major varieties of grafts – Autografts: tissue transplanted from one body site to another.

Introduction of Biomaterials in Medical Fields ( 1 )

O-A-B Blood Types Agglutinogen

ORGAN TRANSPLANTATION

Transplantation Pathology

Organ Transplantation

Transplantation Rejection of foreign tissue grafts is due to immune responses to alloantigens on the graft Blood group antigens Polymorphic MHC antigens.

Organ Transplants & Grafts

3.7 – Organ Transplantation

Presentation transcript:

Organ & Tissue Transplants

What is transplantation? Replacing a damaged, non-functional or missing organ or tissue with an organ or tissue from another donor There are multiple types of transplants: Autografts – From the same persons body Allografts – From another source Isograft – From an identical source (twin or clone) Xenografts – From another species

What can be transplanted? 3 1 Organs 2

What can be transplanted? Tissues 2 1

Autografts Transplant of organ tissue from within the same person Less risk of rejection Examples?

Skin Grafts Bypass Surgery Tommy John Surgery Veins used to bypass coronary blockage Ulnar collateral ligament replaced with one from elsewhere in body

Allografts Transplant of organ tissue from one person to another Most transplants are allografts Donors can be living or deceased Tissues can be stored for transplants up to 5 years Organs last about 24 hours after death Examples?

Kidney Transplant Face Transplant First successful full facial transplant was in Barcelona in 2010

Xenografts Transplant of organ tissue from another species High risk of rejection Lifespan and disease issues But long waitlists for organs make this potentially useful in the future

Received a baboon heart transplant in 1984 Baby Fae Received a baboon heart transplant in 1984 Incompatible blood types (O vs AB) Experimental and contraversial!

Isografts Transplant of organ tissue from identical source Very rare because of requirements, but very successful! Low rejection rate.