Figure 2. Algorithm for the evaluation of asymptomatic neonates after vaginal or cesarean delivery to women with active genital herpes lesions. Kimberlin D W et al. Pediatrics 2013;131:e635-e646 ©2013 by American Academy of Pediatrics

Figure 3. Algorithm for the treatment of asymptomatic neonates after vaginal or cesarean delivery to women with active genital herpes lesions. Kimberlin D W et al. Pediatrics 2013;131:e635-e646 ©2013 by American Academy of Pediatrics

Classification of Maternal Infection PCR/Culture From Genital Lesion Maternal HSV-1 and HSV-2 IgG Antibody Status Documented first-episode primary infection Positive, either virusBoth negative Documented first-episode nonprimary infection Positive for HSV-1Positive for HSV-2 AND negative for HSV-1 Positive for HSV-2Positive for HSV-1 AND negative for HSV-2 Assume first-episode (primary or nonprimary) infection Positive for HSV-1 OR HSV-2 Not available Negative OR not available b b Negative for HSV-1 and/or HSV-2 OR not available Recurrent infectionPositive for HSV-1 Positive for HSV-2 TABLE 2 Maternal Infection Classification by Genital HSV Viral Type and Maternal Serology a a Kimberlin D W et al. Pediatrics 2013;131:e635-e646 ©2013 by American Academy of Pediatrics