The VIZIER project Coord. : B. Canard AFMB, CNRS/University of Marseille France Preparing Europe for the Next Viral Outbreak.

Slides:

Advertisements

Similar presentations

Viruses Dead or alive?.

Advertisements

Partnership levels by Dan FLORESCU Coordinator of BEST Corporate Relations BEST ROUND TABLE 5 th October 2007 Paris, France.

BEST in numbers by Paulina GRUNWALD BEST Corporate Relations BEST PARTNERS ROUND TABLE 5 th October 2007 Paris, France.

The European Union (EU). Overview: Brief History Present/ Future.

Pan American Health Organization World Health Organization Pandemic and Outbreak Communication PAHO/WHO Module 2: IHR Risk communications Capacity: Public.

Predicting the Future: Emerging Pathogens and Infectious Disease Risk Samuel L. Stanley, Jr., M.D.

Table of Contents Section 1 Viral Structure and Replication

If it is not alive, We can’t kill it -- We can only wish to contain it!

What living things do you see in this picture?.

Viruses Small but deadly!. The Black Death o Also known as the Black Plague, was a devastating pandemic that first struck Europe in the mid-late-14th.

Virus Reproduction Overview Cycles for reproduction Lytic Lysogenic Retrovirus HIV Diseases caused by viruses Prevention.

Keeping Europe healthy

Vice Chancellor for RESEARCH Office of the Global Health is America’s Health and National Security Samuel L. Stanley, Jr., M.D. Paul Rogers Global Health.

Ebola Virus Outbreak This presentation has been prepared by Christine H. Herrmann, Ph.D. of the Department of Molecular Virology and Microbiology at Baylor.

Polio Eradication The Good News The Bad News The Good News.

For your Test tomorrow: Study the following: – Virus Structure notes – Viral Reproduction notes – Microorganisms in Society notes (today’s notes & videos)

You must have a long-sleeve lab coat to the knees and safety glasses with peripheral protection RCC Medical Supply th Ave # H103 Greeley, CO (970)

Databases and tools to study the genomes of hundreds of pathogens, plants, and mammals Richard H. Scheuermann, Ph.D. Director of Informatics J. Craig Venter.

Lytic – viral replication cycle resulting in the release of new viruses by breaking open the host cell. Viral DNA directs host cell to make new viruses.

Copyright © by Holt, Rinehart and Winston. All rights reserved. ResourcesChapter menu Viruses Chapter 24 Table of Contents Section 1 Viral Structure and.

VIRUSES Chapter 24 Video.

Whatever You Thought, Think Again.. A Very Delicate Virus Human Immunodeficiency Virus - HIV is full of contradictions – – Very fragile; fresh air destroys.

Emerging Diseases – Ready and Waiting Aileen J Plant Curtin University of Technology 19 October, 2004 Emerging Diseases: the human health perspective.

Inquiry 9/18 and 9/21 Please prepare for a warm-up! Have your Semmelweis flowchart and q’s ready for stamping.

Chapter 24 Video.  Computer Viruses?  Not in the scope of this class. They behave similarly, but are not at all related.

Molecular genetics of HIV-1 strains spreading in Russia Edward Karamov Ivanovsky Institute of Virology, Moscow 4th World Congress on Virology, 6-8 October.

KEY CONCEPT Some viral diseases can be prevented with vaccines.

Edward Bayham, MSBME, MBA Vice President, Business Development IBE 2007 March30,2007 St. Louis, Missouri Automated Antiviral Drug Screening Using Engineered.

General Characteristics of Viruses

HIV and Viruses Lucy Stacey Christella. Viruses  Obligate parasites of living cells  Can’t replicate without living host cell  Due to RNApol, ribosomes,

New Developments in Biothreats and Biosecurity Clifton R. Lacy, M.D. October 17, 2007.

Chapter 18 Reading Quiz 1.Which viral reproductive cycle destroys the host cell? 2.A(n) ______ is a harmless variant or derivative of a pathogen that.

Viruses 4/23/2017.

VIRUSES Poliovirus – RNA virus, affects humans alone video.

 Viruses (2) Biology 11 Mr. McCallum. What do viruses do?  Replicate, replicate, replicate!  Harmful as this leads to the death of the host cell 

Viruses A virus is a NON-Living particle made of DNA or RNA and a protein coat. Look at table 25-1 on p. 487 in text book. VERY small. ~ 0.001micron.

Viral Anatomy Envelope Forms from host membrane Forms from host membrane Viral genome includes genes for surface proteins Viral genome includes genes.

Avian flu?. In humans? Avian Influenza in Humans Silvio Pitlik, MD Mar 17, 2004.

Viruses. Virus A non living particle composed of a nucleic acid and a protein coat A non living particle composed of a nucleic acid and a protein coat.

VIRUSES NONLIVING PARTICLES. Viruses  Smaller than bacteria  Known since late 1800’s but no way to study them  1935 Tobacco mosaic virus was crystallized.

Objectives: Describe the structure of viruses. Explain how viruses cause disease. Explain how humans defend against viral disease.

Viruses Viruses are very small Anatomy of a Virus.

Unit 6 – Organismal Biology Part 1: Bacteria and Viruses

Nonliving infectious agent that can cause disease. *Not in a kingdom

BRAINSTORM. TRUE or FALSE 1. Viruses may contain DNA RNA Glycoprotein Enzymes Cell wall.

Treatment of Infectious Diseases. ›Drugs used to treat bacterial diseases are grouped into categories based on their modes of action Treatment of Bacterial.

Genetics of Viruses. Viral Structure n Virus: – “poison” (Latin) – infectious particles consisting of a nucleic acid in a protein coat n Capsid= viral.

Virus – Virion Virus – a non-living infectious agent Non-living – what does it mean to be ‘living’ Made of cells (nope) Use and obtain energy (not really)

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Virus Families 1.Single-stranded DNA, nonenveloped viruses, polyhedral capsid.

Viruses Video and Transcript by Matthew Dougherty, MS, and Wah Chiu, PhD National Center for Macromolecular Imaging, Baylor College of Medicine PowerPoint.

Viruses. What are viruses? They are not living things. Viruses are considered non-living because they do not use energy to grow or to respond to their.

Discussion Questions Review the binational variable position statement: Does the position statement need to be modified? Would DGMQ provide this information.

Flashback to VIRUSES! What do viruses need to reproduce? Other viruses

Virus DHO chapter 14.

First cases of autochthonous dengue fever and chikungunya fever in France: from bad dream to reality! E.A. Gould, P. Gallian, X. de Lamballerie, R.N.

KEY CONCEPT Some viral diseases can be prevented with vaccines.

Viruses Small but deadly!.

Viruses & Bacteria 1.

First cases of autochthonous dengue fever and chikungunya fever in France: from bad dream to reality! E.A. Gould, P. Gallian, X. de Lamballerie, R.N.

Are Viruses Alive?.

Eu as a superpower 8th January 2014 C/W Learning Objectives –

KEY CONCEPT Some viral diseases can be prevented with vaccines.

KEY CONCEPT Some viral diseases can be prevented with vaccines.

KEY CONCEPT Some viral diseases can be prevented with vaccines.

Presentation transcript:

The VIZIER project Coord. : B. Canard AFMB, CNRS/University of Marseille France Preparing Europe for the Next Viral Outbreak

Major causes of human death: Major causes of human death: Most are RNA viruses.

A today alarming situation

rotavirus virus Ebola virus Hantaan HTLV-1 HIV Hépatite E Hépatite C virus Guanarito / Machupo virus Sin Nombre virus Hendra grippe virus Nipah RVFV virus Chikungunya virus West Nile SARS-CoV virus de la dengue encéphalite Japonaise monkeypox herpesvirus-8 Génome ARN Struct genomic Southern countries BSL Zoonose Arbovirose Vaccines Antivirals Kits S / MB-A Very few weapons to fight them. Killing agents:

Goal : Identification of new targets from RNA viruses through a structural characterization of the replicative system Structural Genomics project supported by the European Union Started in November 2004 up to (at least) October 2008 Means : 25 partners (public and corporate research centers) >100 full time researchers involved 13 M funding by EEC What is VIZIER?: VIral enZymes InvolvEd in Replication A common effort to tackle this issue.

VIZIER members and Partnership Section 1 Bioinformatics Viralis VaZyMolO Alexander Gorbalenya Section 2 Virology Xavier De Lamballerie Section 3 Production Bruno Coutard (vice coordinator) Section 4 Crystallization Alwyn Jones Section 5 Validation Johan Neyts