What is analytical chemistry? 5 subdisciplines of chemistry Some definitions In every day life… Analytical chemist versus chemical analyst
“My” steps 1.Formulate the question 2.Select analytical procedures 3.Sampling** “Representative” sample Homogeneous versus heterogeneous 4.Sample Preparation** Most analyses require a liquid solution: Extraction Digestion 4.Analysis What type of analysis? 6.Manipulate data Statistical analysis 7.Interpret results/draw conclusions 8.Communicate results
Types of Analyses 1.Qualitative analysis 2.Quantitative analysis 3.Characterization analysis 4.Fundamental analysis
Some Terminology Analyte Matrix Analysis – Measurement – Determination Technique – Method – Procedure – Protocol
Classifying Techniques All analyses based on a signal Total Analysis Technique – AKA “Classical Method” Concentration Technique – AKA “Instrumental Method”
Method Considerations: Analytical Figures of Merit (AFOMs) Accuracy Precision Sensitivity Selectivity Robustness Ruggedness Scale of operation, Analysis time Availability of equipment Cost
Relevant Reading Chpt 1 all Chpt 3 to 3C Chpt 2 (review)