Microinjection and Fallopian Transfer (MIFT) - an effective form of Assisted Reproductive Technology(ART) for the treatment of severe male infertility Dr. Milton Leong IVF Centre Hong Kong Sanatorium & Hospital 2-4 Village Road, Happy Valley Hong Kong url: http://www.ivf.com.hk email: ivfcntr@pacific.net.hk

GIFT vs IVF Result-1 Source: Dawood MY, Am J Obstet Gynecol 1996 Apr;174 (4):1208-17

GIFT vs IVF Result -2 Source:SART Registry, Fertility and Sterility 1996 May;71 (5):798-807

1992 1st ICSI Pregnancy report on Lancet by Palermo et. al. 1995 TESE-ICSI pregnancy report on Hum Reprod by Siber et. al. 1999 1st MIFT case report on J Assist Reprod Genet by Allan et. al.

Indications of MIFT Male Factor 83% Idiopathic 13% Antibodies 1% Previously failed IVF 3%

VIDEO SECTION

MIFT Jan 98--May 00

Oocytes Retrieval <40

Oocyte Retrieval <40

Survival and Fertilization Rate <40

Survival & Fertilization Rate <40

Age <40 MIFT Pregnancy Rate

# of Oocytes MIFT’d vs Multiple Pregnancy <40

# of MT II Retrieved vs Pregnancy <40

Oocytes Retrieval >=40

Oocyte Retrieval >=40

Survival and Fertilization Rate >=40

Survival and Fertilization Rate >=40

Age >=40 MIFT Pregnancy Rate

# of Oocytes MIFT’d vs Multiple Pregnancy >=40

# of MT II Retrieved vs Pregnancy >=40

Age vs Pregnancy

MIFT Multiple Pregnancy <40

Evaluation l’copy augmented by MIFT L’copic minor surgery augmented by MIFT Philosophical or religious reasons

MIFT vs ICSI/IVF Results Jan 98 - May 00