Pharmaceutical Dosage Modules Power Point Presentation

Instructions Be sure to work through the problems before attempting to watch the lecture tapes. After working through the problems as much as you can, watch the tapes for the necessary steps needed to solve the problems correctly. Remember practice makes perfect when working dosage problems

Good Luck with the Modules!!!

Dr. R. R. Espinosa, R.Ph., Pharm. D. Pharmacology Dosage Modules I-V

Dosage Modules Module #1 Dimensional Analysis Module #2 Basic Dosage Calculations Module #3 Reconstitution Module #4 Basic IV Dosage Calculations Module #5 Advanced Intravenous Calculations

Pharmaceutical Dosage Module 1 : Dimensional Analysis

Dimensional Analysis Given Quantity: the beginning point of the problem Conversion Factors- Equivalents necessary to convert between systems of measurement and to allow unwanted units to be cancelled from the problem

Dimensional Analysis Unit Path: the series of conversions necessary to achieve the Wanted Quantity Wanted Quantity: the answer to the problem

Converting Within and Between Systems of Measurement

System of Measurement Household: tsp, gtt, T, c Apothecary: gr, dr, oz Metric: ml, mg, g, l

Conversion Problems 350 mg =_______g 0.016 g =_______mg 0.16 kg =_______lb 8 mg = _______gr 0.07 mg =______mcg 500 ml = _______L 45 gr = _______mg

Conversion Problems issgr =_________g xx drams =_____ml 75 ml =________oz vss oz =_______ml 9 g =__________gr 102 lb =_______kg 3 tsp =________ml

Conversions problems 3 ml =_________Minims 4 drams =______oz iv gr =_________mg 25 L = ______ml 1/300 gr =______mg 200ml =________tsp 6 tsp =_________T

Answers to problems Not covered on lecture tape 4drams=0.67oz 4 gr=240mg 25L=25000ml 200ml=40tsp 6tsp=2T

Pharmaceutical Dosage Module 2: Basic Dosage Calculations

Dosage Calculations The doctor orders a patient to receive Daypro 1200mg q am and pm. The stock supply is 600mg/tab. How many tablets will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage Calculations The doctor orders a patient to receive Daypro 1200mg q am and pm. The stock supply is 600mg/tab. How many tablets will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage calculations A patient is to receive Doxycycline 5 gr po qid for infection. The stock supply is 100mg/caps. How many capsules will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage calculations A patient is to receive Doxycycline 5 gr po qid for infection. The stock supply is 100mg/caps. How many capsules will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage Calculations Patient is to receive 0.5 g of Zocor q hs for cholesterol. The stock supply is 20mg/tab. How many tablets will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage Calculations MD orders the client to have 1/8 gr of Estratab qod. The stock supply is 1.25 mg tablet. How many tablets will the patient receive for the correct dose? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Dosage Calculations Patient is to receive 70 mg IM stat of Solu-Medrol. The stock supply is 125mg/2ml. How many ml’s is the patient going to receive for the correct dose? Given Quantity -Dose on Hand Wanted Quantity -Answer

Dosage Calculations Dr orders Trimox 0.5 g q 6 h for infection. The stock supply is 250mg/5ml. The total volume is 100ml. How many ml’s will the patient receive for the correct dose? How may teaspoonfuls will the patient receive for each dose? Given Quantity -Dose on Hand Wanted Quantity -Answer

Dosage Calculations Given Quantity -Dose on Hand Patient is to receive Atropine 0.2mg Sub Q stat, then 0.15 mg every 6 hours as needed. The stock supply is 400mcg/ml. How many ml’s will the patient receive for the first dose? How many ml’s will the patient receive on each subsequent dose? Given Quantity -Dose on Hand Wanted Quantity -Answer

Dosage Calculations -Given Quantity -Dose on Hand Patient is to receive Gentamicin ¼ gr IV q 4 h for infection. The stock supply is 15mg/ml. How many ml’s will the patient receive for the correct dose? How often is this medication given? What is the route of administration? -Given Quantity -Dose on Hand -Wanted Quantity -Answer

Pharmaceutical Dosage Module 3: Reconstitution

Reconstitution The doctor orders Ancef 750mg IM q 8 h. The stock supply is a 1.0 g vial of powdered Ancef. Directions say to reconstitute with 2.5 ml of water to produce a total volume of 3 ml. How many ml’s will you give to the patient for the correct dose? How many mg’s will the patient receive for the correct dose in 24 hours(1 day)? How many grams will the patient receive in 24 hours?

Reconstitution The doctor orders Ancef 750mg IM q 8 h. The stock supply is a 1.0 g vial of powdered Ancef. Directions say to reconstitute with 2.5 ml of water to produce a total volume of 3 ml. How many ml’s will you give to the patient for the correct dose? How many mg’s will the patient receive for the correct dose in 24 hours(1 day)? How many grams will the patient receive in 24 hours?

Reconstitution Patient is to receive 3 g of Ampicillin to be added to a 1000ml D-5-W IV q 8 h. The stock supply is a 10,000mg Ampicillin vial. Directions say to reconstitute with 9.8 ml of NS to yield 500mg/ml. How many ml’s of Ampicillin will you add to the IV bag for the correct dose?

Reconstitution Patient is to receive 3 g of Ampicillin to be added to a 1000ml D-5-W IV q 8 h. The stock supply is a 10,000mg Ampicillin vial. Directions say to reconstitute with 9.8 ml of NS to yield 500mg/ml. How many ml’s of Ampicillin will you add to the IV bag for the correct dose?

Reconstitution Patient is to receive Nafcillin 5 gr IM q 6 hours for infection. The stock supply is a 2 g vial. The directions say to add 6.6 ml of sterile water to yield 250mg/ml. The total volume in the vial is 8ml. How many ml’s will the patient receive for the correct dose? How often is the patient receiving the medication?

Reconstitution Suprax 0.4g po q d for 12 days is order for a patient for infection. The stock supply is a 2 g bottled powder. The directions says to reconstitute with 69 ml of water. This will provide 100mg/ml. How many ml’s will the patient receive for one dose? What would be the total ml’s for the entire dose?

Reconstitution Client is to receive Cephalexin 2 g IV qid for infection. The stock supply is a 2 gram vial. Directions say to add 5ml of sterile water for injection, this will yield a concentration of 160mg/ml. How may ml’s will the patient receive for the correct dose? How often is the patient to receive this dose?

Reconstitution MD orders Timentin 8 gr IV tid. Timentin is available in a 3.1g powder. Directions say to use 13 ml of sterile water for injection. The concentration will be approximately 200mg/ml. How many ml’s will be administered for the correct dose?

Pharmaceutical Dosage Module 4: Basic IV Dosage Calculations

Calculating Intravenous Flow Rates Electronic vs. Manual Infusion Devise

Electronic IV flow rate pump delivers volume in ml/hr Nurses responsibility to program the pump Amount of fluid/over period of time

Manual IV flow rate must be determined in gtts/min Nurses responsibility to count the number of drips that drop in a minute into the drip chamber The IV tubing provides the drop factor, which is calibrated in drops/ml

Basic IV Calculations A client on an infusion pump is to receive an antibiotic in 50 ml 0.9% NS over 30 minutes. What is the flow rate in ml per hour? Given Quantity Wanted Quantity Answer

Medication involving Intravenous pump A client on an infusion pump is to receive 500ml of R/L in 12 hours. What is the flow rate in ml per hour? Given Quantity Wanted Quantity Answer

Medication involving Intravenous pump The doctor orders 100ml of D-5-W to infuse in 20 minutes q 4 hours. What is the flow rate in ml/hr? Given Quantity Wanted Quantity Answer

Medication Problem Involving a Drop Factor The doctor orders 150 ml of D5W to be infused over 45 minutes q 4 hours. The drop factor is 20 gtts per ml. What is the flow rate in drops per minute? Given Quantity Wanted Quantity Drop factor Answer

Basic IV Calculations The doctor orders 250 ml of D-5-W IV q 3 hours. The drop factor is 20 gtts/ml. What is the flow rate in gtts/min? What is the flow rate in ml/hr? Given Quantity Wanted Quantity Drop Factor Answer

Pharmaceutical Dosage Module 5: Advanced Intravenous Calculations

The MD orders 10,000 units of Penicillin to be added to the IVPB of 100ml of NS to infuse in 45 minutes every 6 hours. Stock supply is a vial containing 2,000,000 units of Penicillin. Directions says to reconstitute with 9.8 ml to yield a 10 ml total volume. The drop factor for the IVPB is 15 gtts/ml. How many ml’s of penicillin will you add to the IVPB for the correct dose? What is flow rate in gtts per min for the IVPB? What is the flow rate in ml per hour?

What is the flow rate in gtts per min for the IVPB? The MD orders 10,000 units of Penicillin to be added to the IVPB of 100ml of NS to infuse in 45 minutes every 6 hours. The stock supply is a vial containing 2,000,000 units of Penicillin. Directions says to reconstitute with 9.8 ml to yield a 10 ml total volume. The drop factor for the IVPB is 15 gtts/ml. How many ml’s of penicillin will you add to the IVPB for the correct dose? What is the flow rate in gtts per min for the IVPB? What is the flow rate in ml per hour?

Advanced Intravenous Calculations Dopamine 2mcg/kg/min is order for a patient. The pharmacy sends an IV bag labeled: Dopamine 400mg/ 250 ml D5W. The client weighs 150 lbs. -What is the flow rate in ml’s per hour? Given Quantity -Dose on Hand Wanted Quantity -Answer

Advanced Intravenous Calculations MD orders Nipride 3mcg/kg/min. The pharmacy sends a bag labeled: Nipride 50mg/ 250 ml of NS. The drop factor is 15 gtts/ml. The patient weighs 110 lbs. -Calculate the ml/hr to set the IV pump? -What is the flow rate in gtts/min? Given Quantity -Dose on Hand Wanted Quantity -Answer

Advanced Intravenous Calculations Dobutamine 500mg in 250 ml D5W to infuse at 10mcg/kg/min. The client weighs 250 lbs. -What is the flow rate in ml/hr? -What is the flow rate in drops/minute with a drop factor of 60 gtts/ml? Given Quantity -Dose on Hand Wanted Quantity -Answer

Conclusion I hope this has helped you achieve yours goals of understanding different types of dosage calculations that you will encounter in this class and on into your careers. Good Luck, Allied Health Science Faculty