Minimally-Invasive, Non-Surgical Treatment Cryoablation Minimally-Invasive, Non-Surgical Treatment for Kidney Cancer The Johns Hopkins Hospital

52000 new cases per year in the USA Kidney Cancer 52000 new cases per year in the USA 75% are incidentally discovered when patients are examined for other reasons. Because of utilization of Cat scans, Ultrasounds and MRIs by Radiologists This Incidental detection results in improved long term survival/cure rate because many caught early- now70% (40% in 1960’s)

Kidney Cancer in the US 52000

Percutaneous ablation Treatment options Removal of whole kidney Removal of tumor and surrounding part of kidney Open surgery vs laparoscopic surgery or ablation Percutaneous ablation

Percutaneous Cryoablation A thin, needle-like, probe is directed from the skin into the tumor NO INCISION or SURGERY Under direct visualization using a CAT scan or Ultrasound The probe freezes the tumor to lethal sub-zero temperatures Probe is thawed and removed Under minimal sedation NO GENERAL ANESTHESIA

Size of Kidney Cancers Treated with Cryoablation

Percent of kidney cancers completely treated (Success rate) 1-year follow up < 1-year follow up

What happens to the Cancer after treatment?

Before After

Minimally-Invasive Cryoablation for Kidney Cancer Cryoablation can be a curative treatment option for patients with kidney cancer 4 cm or less-success rate is 97% * Even patients with larger tumors can benefit from this procedure especially those who cannot have general anesthesia or surgery * Half of patients go home same day, the rest after one night’s stay