Introduction to Analytical Chemistry

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Presentation transcript:

Introduction to Analytical Chemistry Dr Carl Hall X1/12 c.e.hall@hud.ac.uk SFC1004 Analytical Science 1

What is Analytical Chemistry? The resolution of a chemical compound into its proximate or ultimate parts; the determination of its elements or of the foreign substances it may contain.

What is Analytical Chemistry? Qualitative Analysis Quantitative Analysis

What is Analytical Chemistry? Qualitative analysis The determination of the components of an unknown sample. Organic spectroscopy

What is Analytical Chemistry? Quantitative analysis The determination of the quantity of the components in a sample. Classical methods

What is Analytical Chemistry? Forensic Science Medicine Physics Analytical Science Materials Science Biochemistry Organic Chemistry Physical Chemistry

Applications Fundamental Research Product Development The formulation of new drugs and the examination of meteorites. Product Development Development of alloys and polymer composites. Product Quality Control Analysis of raw materials and finished products.

Applications Monitoring and Control of Pollutants Assay Heavy metals and pesticides. Assay The metal content of ores. Medical and Clinical Studies Indicators of physiological disorders. Food Analysis Labelling and provenance

Glossary of Terms Accuracy Analyte Assay Background Blank Calibration Concentration Constituent Detection Limit Determination Equivalent Estimation Interference Internal Standard Masking Matrix

Glossary of Terms Method Precision Primary Standard Procedure Reagent Sample Sensitivity Standard Standard Addition Standardisation Technique Validation

Analytical Techniques Chemical analysis is an indispensable servant of modern technology whilst it partly depends on that modern technology for its operation. The two have developed hand in hand.

Analytical Techniques Classical Techniques Instrumental Techniques Historically derived and artificial

Analytical Techniques

Analytical Problems and their Solution The solutions of all analytical problems, both qualitative and quantitative follow the same basic pattern which can be described under seven general headings.

Analytical Problems and their Solution Choice of method Sampling Preliminary sample treatment Separations Final measurement Method validation Assessment of the results