Bone-Marrow Transplantation in Sickle-Cell Disease. Effect on Osteonecrosis: A Case Report with a Four-Year Follow- up* by P. HERNIGOU, F. BERNAUDIN, P.

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Presentation transcript:

Bone-Marrow Transplantation in Sickle-Cell Disease. Effect on Osteonecrosis: A Case Report with a Four-Year Follow- up* by P. HERNIGOU, F. BERNAUDIN, P. REINERT, M. KUENTZ, and J. P. VERNANT J Bone Joint Surg Am Volume 79(11): November 1, 1997 ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 1 Radiograph made before the bone-marrow transplantation, showing osteonecrosis and evident collapse of the humeral head (arrow). P. HERNIGOU et al. J Bone Joint Surg Am 1997;79: ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 2 T1-weighted magnetic resonance imaging scan of the shoulder, showing low signal intensity in the entire epiphysis. P. HERNIGOU et al. J Bone Joint Surg Am 1997;79: ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 3 Radiograph of the shoulder, made three months after the transplantation, showing the reconstruction of the proximal humeral epiphysis. P. HERNIGOU et al. J Bone Joint Surg Am 1997;79: ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 4 T1-weighted magnetic resonance imaging scan of the shoulder, made three months after the transplantation, showing high signal intensity in the proximal humeral epiphysis (arrow). P. HERNIGOU et al. J Bone Joint Surg Am 1997;79: ©1997 by The Journal of Bone and Joint Surgery, Inc.

Fig. 5 Coronal magnetic resonance imaging scan of the shoulder, made four years after the transplantation, showing regions of high signal intensity (arrows) that indicate the high fat content of the proximal humeral epiphysis. P. HERNIGOU et al. J Bone Joint Surg Am 1997;79: ©1997 by The Journal of Bone and Joint Surgery, Inc.