Iwona Poziomkowska- Gęsicka MD PhD

Slides:

Advertisements

Similar presentations

Introduction to ALLERGIES.

Advertisements

Table de multiplication, division, addition et soustraction.

It is 2 o C The temperature drops by 3 degrees What temperature is it now? -1 o C.

Clinical Audit on: The Clinical Guidelines for Prescription of Epinephrine Auto Injectors (Epipen, Anapen) for Food Allergy in The Paediatric Allergy Clinic.

23-8 3x6 Double it Take Away 6 Share By 9 Double it +10 Halve it Beginner Start Answer Intermediate 70 50% of this ÷7÷7 x8 Double it Start Answer.

2 x0 0 12/13/2014 Know Your Facts!. 2 x1 2 12/13/2014 Know Your Facts!

2 x /10/2015 Know Your Facts!. 8 x /10/2015 Know Your Facts!

Strategies – Multiplication and Division

5 x4. 10 x2 9 x3 10 x9 10 x4 10 x8 9 x2 9 x4.

The Problem of K Maximum Sums and its VLSI Implementation Sung Eun Bae, Tadao Takaoka University of Canterbury Christchurch New Zealand.

Multiplication Facts Practice

Graeme Henchel Multiples Graeme Henchel

0 x x2 0 0 x1 0 0 x3 0 1 x7 7 2 x0 0 9 x0 0.

MULTIPLICATION OF INTEGERS

Count to 20. Count reliably at least 10 objects. Use ‘more’ and ‘less’ to compare two numbers. Count reliably at least 10 objects. Estimate number of objects.

Acute Angioedema Gabriele de Vos, M.D., M.Sc. Division of Allergy and Immunology Jacobi Medical Center Albert Einstein College of Medicine.

Food Allergy Update Thomas Flaim, M.D.. Prevalence of Food Allergy Prevalence rate is 6% in children < 3 years of age; 4% in adults Prevalence rate is.

GIRISH VITALPUR, MD, FAAP, FAAAAI ASSISTANT PROFESSOR OF CLINICAL PEDIATRICS, RILEY CHILDREN’S HOSPITAL, INDIANA UNIVERSITY SCHOOL OF MEDICINE, INDIANAPOLIS,

ALLERGY. No. 1 Hypersensitivity An allergy is a reaction of your immune system to something that does not bother most other people. People who have allergies.

2) A practice exam for exam 5 Learning objectives for exam 5

Immunopathological reaction type IV (delayed type). Cutaneous and mucous contact allergy. IgE mediated immunopathological reaction (type I, atopy). Allergens.

Treat Allergies Not Just The Symptoms!™ ”WITHOUT NEEDLES”

Drug treatment of asthma The University of Western Australia Integrated Paraclinical Sciences Case History Initial consultation: Personal details: Fred.

Better Health. No Hassles. Hay Fever. Better Health. No Hassles. HAY FEVER Hay fever also called allergic rhinitis Unlike a cold, hay fever isn’t caused.

Cedar seeds are found in mountainous areas - most commonly in Arkansas, Missouri, Texas and Mexico. Although most cedars pollinate and cause allergy symptoms.

Asthma and Allergy  Atopy v Allergy  Asthma Aeroallergens – indoor & outdoor Aeroallergens – indoor & outdoor  Occupational allergens.

Immunopathological reaction (reaction of hypersensitivity) type I.

Allergy, Anaphylaxis & Immune Reactions Christine Kennedy & Katharine Smart.

The Immune System and Allergy William L. Houser, Jr., M.D.

J. Antipkin 1, T. Umanets 1, V. Lapshyn 1, A. Nakonechna 2 1) Institute of Pediatry, Obstetrics and Gynaecology, Kiev, Ukraine 2) Royal Liverpool and Broadgreen.

Allergy Testing Melisa Steele, CPNP

HYPERSENSTIVITY Hypresensitivity causes reproducible symptoms and sings initiated by exposure to defined stimulus that is tolerated by „normal” people.

Allergic Disease. Atopy The predisposition to produce high quantities of Immunoglobulin (Ig)-E Immediate (Type I hypersensitivity) Mast cells, basophils,

Hypersensitivity. Anaphylaxis Nafiseh Kiamanesh Learning Objectives Knowledge of the mechanism which causes anaphylaxis and the agents which are most.

HYPERSENSITIVITY REACTIONS Innocous materials can cause hypersensitivity in certain individuals unwanted inflammation damaged cells and tissues.

Allergic Rhinitis Richard Douglas. Prevalence Most common disease 20% adult population.

ALLERGOLOGY The branch of medical science that studies the causes and treatment of allergies.

L ECTURES 2014 KEFAH F. HASSOON L ECTURE N O. 1 Immune System Disorders Auto-immune Diseases Hypersensitivity reactions.

Rhinosinusitis Dr. Abdullah S. Al Yousef. Allergic Rhinitis Definition : An inflammatory disorder of the nose which occurs when the membranes lining the.

Hypersensitivity Reactions. Injurious, patologic immune reactions causing tissue injury and disease Excessive or aberrant immune response to: Foreign.

Type I Hypersensitivity (Allergy and Anaphylaxis.

Allergy in 10 minutes DETECTIVE WORK Presenting episode Previous episodes Consistent trigger or pattern to episodes Contacts/Foods in previous 4 hours.

E. Simko WCVM Healing: First intention Second intention Prerequisites for healing: Debridement Tissue scaffold Germinal cells Blood supply Reference reading:

Hypersensitive Reactions. Immunopathology Exaggerated immune response may lead to different forms of tissue damage 1) An overactive immune response: produce.

DRUG INTERACTIONS. –Adverse drug effects –Hypersensitivity –Anaphylactic reactions.

Review Questions and Answers Chapters 13-15

Hypersensitivity reactions

Diseases Hypersensitivity- Types

Prevalence of Asthma, Rhinitis and Eczema in Saudi Arabia * Physicians’ diagnosed Asthma + highly suspected asthma * * 1986: n=2123, 1995: n=1008, 2001:n=1014.

Jonathan Wilkin, M.D. Director, Division of Dermatologic and Dental Drug Products, FDA URTICARIA: Overview and OTC Considerations April 22, 2002.

ALLERGY Nada AL-Juaid. Definition  It is an appropriate and harmful immune response to normally harmless substances.  It is usually caused by allergen.

Amoxicillin Infant Sleepy Cheap Amoxicillin Canadian Pharmacy amoxicillin asthma problems amoxil tooth abcess can you drink alcohol when taking amoxicillin.

Long-term Mortality Among Adults With Asthma A 25-Year Follow-up of 1,075 Outpatients With Asthma Zarqa Ali, MD; Christina Glattre Dirks, MD, PhD; and.

Amoxicillin To Buy Over The Counter France Amoxicillin Cheap amoxicillin root canal treatment over counter amoxicillin antibiotic uk amoxicillin rash remedy.

Hypersensitivity Type III and IV. Classification of Hypersensitivity TypeMechanismExample I IgE mediatedSystemic anaphylaxis eg peanut allergy Asthma.

Allergy. Introduction An allergy is an exaggerated reaction between the immune system and certain foreign substances called as allergens. It is called.

Allergology. Basic concepts n Allergy is an inappropriate and harmful response to normally harmless substance n Allergy is usually caused by proteins.

Dr Mazen Qusaibaty MD, DIS / Head Pulmonary and Internist Department Ibnalnafisse Hospital Ministry of Syrian health – Dr Mazen.

Catherine M. Bettcher, M.D. CME Director & Assistant Professor, Department of Family Medicine, University of Michigan No Nuts Allowed: Food Allergies in.

Diagnosis of cell-mediated responses

Selecting Allergen for BAT

Oral immunotherapy and omalizumab for food allergy

Diagnosing and Managing Common Allergies

Food Allergies: Diagnosis & Management

Get a Detailed Diagnosis for Your Allergy

Allergy Testing in Children

Diagnosis of cell-mediated responses

Kounis syndrome caused by anaphylaxis without skin manifestations after cefazolin administration Hidenori Adachi, MD, Madoka Ihara, MD, PhD, Yuhei Nojima,

Prevalence of Asthma, Rhinitis and Eczema in Saudi Arabia * Physicians’ diagnosed Asthma + highly suspected asthma * 1986: n=2123, 1995: n=1008, 2001:n=1014.

Presentation transcript:

Iwona Poziomkowska- Gęsicka MD PhD Anapylaxis? Iwona Poziomkowska- Gęsicka MD PhD

M 41 y.o Appointment Shock after use cefuroxyme, Asthma Hay fever received with aim of selection of safe antibiotic

Identification of factor History Identification of factor Anapylaxis: III 2007; urticaria after licking teaspoon with drop Cefuroxyme (15 min past)

Identification of factor History V 2007, it was ill and received orally Cefuroxyme, 15 min past 1 dose: pruritus, erythema, runny nose, lack of space in throat, dyspnoe, loss of consciousness – stay in hospital

Identification of factor History X 2007; with reason of ill of ear received the ointment - Cefuroxyme, after 10 min.: pruritus, erythema,dyspnoe, shiver History in the past: Tolerate cefuroxyme (Zinnat) in II 2006

History From 2003r. – Asthma treatment: GCS – inh. β2-agonist , antyhistamines. From 2006r. – Hay fever- Immunotherapy : 70% grass 30% weeds (motherword).

Family history Child – food allergy Grandpa - asthma

In examination and spirometry – without deviation

Amaphylaxis III0 on Cefuroxyme Hypersensitivity First Diagnosis Amaphylaxis III0 on Cefuroxyme Asthma Hay fever

Hypersensitivity allergic or not Skin prick tests positive with pollen: Tree, weeds, grass, Alternaria i Cladosporium, cat, dog, DM .

Hypersensitivity allergic or not Skin prick tests & intradermal test with penicyllin- negative.

Hypersensitivity allergic or not Tests (diameter of wheal mm after 20 min) Badana substancja prick tests 1:1 intradermal tests (histamina 6x6) 1:1000 1:100 1:10 Płyn kontrolny – Histamina 5 X Testarpen Penicylina kryst. 5x105 IE/ml Ampicylina 25mg/ml Amoxicillin 25mg/ml Ceftazydym Ceftybuten Ceftriakson 2x2 6x4 6x5 9x8 Cefuroksym 15x16mm + pseudopodia not made po 24 h brak odczynów opóźnionych w miejscach wykonania prób skórnych 13

Hypersensitivity allergic or not

Hypersensitivity allergic or not

Hypersensitivity allergic or not RAST Specyfic IgE aganst penicyllin - negative

Allergic IgE mediated hypersensitivity Final diagnosis Anaphylaxis I i III degree, hypersensitivity IgE – dependent on cefuroxyme. Asthma Hay fever.

Selection of safe antibiotic Oral provocation tests. Complete dose Results penicyllin cryst. 1 mln negative amoxicillin 1000mg ceftybuten 400mg

Selection of safe antibiotic Tests after provocation Tests (diameter of wheal mm after 20 min) Badana substancja prick tests 1:1 intradermal tests 1:1000 1:100 1:10 Płyn kontrolny – Histamina 4 X 5x6 Testarpen Penicylina kryst. 5x105 IE/ml Ampicylina 25mg/ml Amoxicillin 25mg/ml Ceftazydym 5x5 6x7 Nie wykonano Ceftybuten Nie wykonano po 24 h brak odczynów opóźnionych w miejscach wykonania prób skórnych 19

Selection of safe antibiotic After provocation tests: skin pric & intradermal with penicyllin- negative. After provocation tests: skin pric & intradermal with ceftazydym, ceftybuten - positive, conversion of skin reaction.

Allergic IgE mediated hypersensitivity Recommendation Allergic IgE mediated hypersensitivity The prohibition of applying the cefuroxyme Contrindication use ceftriakson, ceftybuten & ceftazydym. It the tolerance of crystalline penicillin was confirmed was as well as the amoxicillin in test of provocation, these penicillins were not observed after provocation the conversion of skin reactions. Treatment: asthma and hay fever.