Blood samples available from study participants with myocardial infarction and controls by ethnic origin Matthew J McQueen, et al. Lancet 2008; 372: 224-33.

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Presentation transcript:

Blood samples available from study participants with myocardial infarction and controls by ethnic origin Matthew J McQueen, et al. Lancet 2008; 372:

Concentrations of lipids and their ratios in cases and controls Matthew J McQueen, et al. Lancet 2008; 372:

Mean concentrations of lipids, lipoproteins, apolipoproteins and their ratios in the control population of men and women by ethnic origin Matthew J McQueen, et al. Lancet 2008; 372:

Risk of myocardial infarction for increasing decile medians (adjusted for age, sex, and region) of (A) lipids, lipoproteins, and apolipoproteins and (B) ratios of apolipoprotein B/apolipoprotein A1 and total cholesterol/HDL cholesterol Note the doubling scale on the y axis for both fi gures. ApoA1=apolipoprotein A1. ApoB=apolipoprotein B100. Matthew J McQueen, et al. Lancet 2008; 372:

Change in risk for myocardial infarction with a 1 SD change in each of the lipid measures in each ethnic group Matthew J McQueen, et al. Lancet 2008; 372:

Change in risk (odds ratio, 95% CI) of myocardial infarction overall and within each ethnic group with a 1 SD change in each of the ratios Matthew J McQueen, et al. Lancet 2008; 372:

Prediction of risk by age with a 1 SD change in each lipid measure Matthew J McQueen, et al. Lancet 2008; 372:

Population-attributable risks for ratios of total cholesterol to HDL cholesterol and apolipoprotein B100/apolipoprotein A1 Matthew J McQueen, et al. Lancet 2008; 372:

Odds ratio (95% CI) of myocardial infarction by tertiles for apolipoprotein B100 (ApoB)/apolipoprotein A1 (ApoA1) and total cholesterol (TC)/HDL cholesterol (HDL C) ratios Matthew J McQueen, et al. Lancet 2008; 372: