Chapter 4 - Tissues

Tissues Definition Types A group of closely associated cells that work together to perform a specific function Types Epithelial - covering Connective - support Muscle - movement Nervous - control

Epithelial Tissue or Epithelium Sheet of cells that covers a body surface or lines a body cavity “epithe” = laid on, covering

Epithelium Occurs in the body as: Covering and lining epithelium Forms the outer layer of skin, dips into and lines the open cavities of the cardiovascular, digestive, and respiratory system, and covers the walls and organs of the ventral body cavity. Glandular epithelium Forms the glands of the body.

Epithelium- Functions Protection Absorption Filtration Excretion Secretion Exocrine glands – secretions released onto apical surface Endocrine glands – secretions into interstitial fluid or blood (hormones) Sensory reception Has sensory nerves (smell, taste, sight, and hearing)

Epithelium– Special Characteristics Polarity Apical surface – upper free surface that is exposed to body exterior or the cavity of an internal organ. May have microvilli, cilia, or be smooth Basal surface – Lower attached surface Basal lamina – non cellular, adhesive sheet (consists mainly of glycoproteins) that lies adjacent to basal surface. Acts as a filter and a scaffolding so cells can migrate to repair a wound

Epithelium– Special Characteristics Specialized Contacts Cells are fit very close together to form continuous sheets Cells are bound together by tight junctions and desmosomes Supported by Connective tissue All rest upon and are supported by connective tissue Basement membrane – made up of the reticular lamina and the basal lamina

Epithelium– Special Characteristics Avascular but innervated Avascular – contains no blood vessels. Cells get nourishment by substance diffusing from blood vessels from the underlying connective tissue Innervated – supplied by nerve fibers Regeneration Reproduce themselves rapidly

Epithelial Tissue Classification Number of cell layers Simple – only a single layer of cells Stratified – Several layers of cells Shape of exposed cells Squamous – flattened/scalelike Cuboidal - boxlike Columnar – tall and column shaped

Epithelial Tissue – Simple Squamous Description Single layer of flattened cells with disc-shaped central nuclei Most delicate Functions Allows passage of materials by diffusion & filtration Secretes lubricating substances in serosae Locations Air sacs of lungs, walls of heart/blood vessels, lining of ventral body cavity (serosae)

Epithelial Tissue – Stratified Squamous Description Several cell layers – basal cells are cuboidal/columnar and surface cells are flattened. Functions Protects underlying tissues in areas where mechanical stresses are severe Locations Skin; lining of mouth, vagina, and esophagus,

Epithelial Tissue – Simple Cuboidal Description Single layer of cube-shaped cells with large spherical nuclei Functions secretion, and absorption Locations Kidney tubules; ducts and glands; ovary surface

Epithelial Tissue – Stratified Cuboidal Typically has two layers of cuboidal cells. Rare Found in ducts of some larger glands Sweat glands, mammary glands

Epithelial Tissue – Simple Columnar Description Single layer of tall column-shaped cells with round to oval nuclei. Some may have cilia or mucus secreting glands Functions Absorption, secretion (mucus, enzymes), propulsion (ciliated) Locations Digestive tract, gallbladder, bronchi, uterine tubes (ciliated)

Epithelial Tissue – Stratified Columnar Only apical layer of cells are columnar Rare Found in pharynx, male urethra, and lines some glandular ducts. Also found at transition areas of junctions between two other types of epithelia.

Epithelial Tissue – Pseudostratified Columnar Description Single layer of cells of differing heights, some not reaching the free surface May possess cilia or goblet cells Functions Secretion or propulsion of mucus by cilia Locations Cilia – trachea and upper respiratory tract No cilia – male sperm ducts, and large ducts

Epithelial Tissue – Transitional Description Resembles both stratified squamous and stratified cuboidal. Basal cells cuboidal/columnar and surface cells are dome shaped or squamous depending on the degree of organ stretch Function Stretches readily and permits distension of bladder Location Lines ureters, bladder, and part of the urethra

Glandular Epithelia Gland – consists of one or more cells that make and secrete (export) a particular product called a secretion. Secretion – an aqueous solution that usually contains proteins Two types: Endocrine Exocrine

Glandular Epithelia - Endocrine Called ductless glands because they lose their ducts Produce hormones that are excreted directly into the extracellular space Structurally diverse, so one general description won’t do

Glandular Epithelia - Exocrine All secrete their products onto body surface or into body cavities Numerous and diverse – mucous, sweat, oil, salivary glands, liver (bile), pancreas (digestive enzymes) Types: Unicellular Multicellular