Ch16 Limb Formation. Limb Disc surrounded by Limb Field.

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Presentation transcript:

Ch16 Limb Formation

Limb Disc surrounded by Limb Field

Limb Disc surrounded by Limb field What happens when limb disc is removed?

Limb Buds What determines type of limb?

Mutual Induction Effect of AER on Limb Development

AER is necessary for limb development

Sonic Hedgehog Expression

Hox Gene Expression

Feedback between AER and ZPA

Digit formation Shhh gene expression BMP concentration

Inhibition of cell death by inhibiting BMP

Which tissue controls Programmed Cell Death? Meso Ecto Duck leg + Chicken leg  ? Chick leg + Duck leg  ? What triggers Programmed Cell Death?