Ois generalPCPCryptococcus-Toxoplasma

OIs- 10 OIs are the most common presentation of chronic treated HIV infection

OIs– 10 No

OIs - 20 OIs usually present when CD4< 300

OIs – 20 No usually when CD4 < 200

OIs - 30 The most common OI in HIV infection

OI – 30 Oral candidiasis

OI - 40 Name 2 of the most life threatening OIs

OI– 40 PCP Cryptococcosis

OI- 50 CMV presents when CD4 < 50 and prophylaxis with antivirals should be started

OI– 50 Antivirals are not part of prophylaxis for HIV related OIs

PCP - 10 One of the most common causes of death from AIDS in 80s

PCP – 10 Yes

PCP- 20 PJP is a common environmental parasite

MHC – 20 IT is a fungus not a parasite

PCP- 30 Drug of choice for PCP prophylaxis and alternative if patient has allergy

PCP– 40 Diagnostic test of choice for PCP

PCP- 40 Diagnostic test of choice for PCP

PCP– 40 Sputum DFA for PCP

PCP- 50 One scenario that patient should stay on prophylaxis for PCP for life

PCP– 50 If patient had episode of PCP with CD4 > 200

Cryptococcus- 10 The most common manifestation of cryptococcus infection

Cryptococcus– 10 CNS infection

Cryptococcus- 20 Why frequent LPs are needed with crypto meningitis?

Cryptococcus– 20 Increased ICP

Cryptococcus - 30 Name two diagnostic tests for Cryptococcus infection

Cryptococcus– 30 Cryptococcus antigen Fungal culture

Cryptococcus - 40 Name the induction therapy for Cryptococcus

Cryptococcus– 40 Amphotericin + 5FC

Cryptococcus - 50 This regimen has been used in resource poor countries for treatment of Cryptococcus infection

Cryptococcus– 50 High doses fluconazole (>800 mg) plus 5FC

Toxoplasma- 10 Name 2 presentation of toxoplasmosis

Toxoplasma- – 10 Fever, headaches, seizures, no clinical manifestations

Toxoplasma - 20 A common carrier of toxoplasma (animal)

Toxoplasma– 20 Cat

Toxoplasma - 30 The antibiotic that is used for prophylaxis for Toxoplasma is also effective for other OIs

Toxoplasma– 30 Bactrim is also effective against PCP

Toxoplasma- 40 Name alternative antibiotics for Toxoplasma (if there is allergy to the drug of choice)

Toxoplasma– 40 Clindamycin, pyrimethamine

Toxoplasma- 50 Duration of prophylaxis for toxoplasma

Toxoplasma- 50 Discontinue ppx when CD4>200 > 3 months