Edward P. Sloan, MD, MPH, FACEP ED Ischemic Stroke Patient Management: Optimal Diagnostic and Treatment Strategies

Edward P. Sloan, MD, MPH, FACEP European Society for Emergency Medicine

Edward P. Sloan, MD, MPH, FACEP 4 th EuSEM Congress Crete, Greece October 5-7, 2006

Edward P. Sloan, MD, MPH, FACEP Edward P. Sloan, MD, MPH Professor Department of Emergency Medicine University of Illinois College of Medicine Chicago, IL

Edward P. Sloan, MD, MPH, FACEP

Thank you to AstraZeneca Neuroscience for their support of these educational programs

Edward P. Sloan, MD, MPH, FACEP

Overview Mission Statement –Patients with neurological emergencies deserve quality emergency care. –Quality scientific research. –Case-oriented, evidence-based medical education on optimal acute neurological care. –Use of technology to break down space and time barriers. –Advocacy.

Edward P. Sloan, MD, MPH, FACEP Education Educational Activities to Date –60 Meetings –180 Speakers –380 Lectures –350+ Lectures posted on the FERNE website –13 Lectures posted on the EMedHome website –97% Evaluations good or excellent –4800+ EM professionals –7500+ contact hours over 9 years

Edward P. Sloan, MD, MPH, FACEP Education Branded Product: Case-based Learning –Case presentation –Key Clinical Questions –Introduction, the clinical disease state –Optimal ED management strategies –Patient outcome –References, Annotated bibliography –Key Learning Points –Questions and answers

Edward P. Sloan, MD, MPH, FACEP Education Web-based Learning: Video Slideshows Audio, video and slide content Audio, video and slide content Able to access individual slides for specific content Able to access individual slides for specific content MS Producer, viewable with Windows Media Player MS Producer, viewable with Windows Media Player

Edward P. Sloan, MD, MPH, FACEP Education Web-based Learning: Slide Lectures Download or view online

Edward P. Sloan, MD, MPH, FACEP Education Web-based Learning: Webcasting Live simulcasts using Centra Symposium

Edward P. Sloan, MD, MPH, FACEP Education Handheld Software: HandiStroke Rx HANDi Stroke Rx Available free from Written at Mount Sinai, New York Funded by a FERNE grant NIH Stroke Scale tPA Inclusion/Exclusion criteria tPA dosage calculator Continuation of care orders

Edward P. Sloan, MD, MPH, FACEP Education Educational Materials Acute Stroke Materials Developed a handbook and companion CD Rom Published Spring 2004 Collaboration included American Stroke Association and France Foundation

Edward P. Sloan, MD, MPH, FACEP Education Web-based Learning: EMedHome.com FERNE generated content FERNE generated content CME can be obtained via the EMedHome website CME can be obtained via the EMedHome website Slides and audio Slides and audio

Edward P. Sloan, MD, MPH, FACEP Education Web-based Learning: Abstract Search Topic specific abstract searches

Edward P. Sloan, MD, MPH, FACEP Research Directed Neurological Emergencies Research Grant –$ 25-50,000 per grant –Emergency Medicine Foundation (EMF) –Promotes new knowledge relating to the diagnosis and acute management of neurological emergencies –Directed to Emergency Medicine researchers

Edward P. Sloan, MD, MPH, FACEP Research Seed Grants / Unsolicited Proposals Up to $5,000 grants Promote new research Help secure future funding Identify the support source Specific area of interest Available for all EM practitioners

Edward P. Sloan, MD, MPH, FACEP

Update on the Care of Emergency Department Transient Ischemic Attack Patients

Edward P. Sloan, MD, MPH, FACEP ED Transient Ischemic Attack Patient Management: Can At-risk Ischemic Stroke Patients Be Identified?

Edward P. Sloan, MD, MPH, FACEP Andrew Asimos, MD, FACEP Adjunct Associate Professor Department of Emergency Medicine University of North Carolina School of Medicine at Chapel Hill

Edward P. Sloan, MD, MPH, FACEPConclusions Future imaged based TIA definition? Isolated visual or sensory symptoms suggest low short term risk for stroke Pace and setting of work up dependent on perceived short term risk Prediction rules require prospective validation

Edward P. Sloan, MD, MPH, FACEP ED Transient Ischemic Attack Patient Management: What Role for Outpatient Evaluation and Disposition?

Edward P. Sloan, MD, MPH, FACEP Michael A. Ross MD, FACEP Associate Professor Emergency Medicine Department of Emergency Medicine William Beaumont Hospital Wayne State University School of Medicine

Edward P. Sloan, MD, MPH, FACEPConclusions Yes. An outpatient evaluation of ED TIA patients can occur successfully. ED evaluation to include H & P, labs, EKG, CT Head (non-contrast), carotid doppler (CTA) evaluation Must be able to detect clinically treatable causes of TIA and CVA (carotid occlusion, cardioembolic sources) Important work given reimbursement trends (prevent admits)

Edward P. Sloan, MD, MPH, FACEP ED Ischemic Stroke Patient Management: Optimal Diagnostic and Treatment Strategies

Edward P. Sloan, MD, MPH, FACEP Stroke Care within the 3 Hour IV tPA Window: Why IV tPA, or What Alternatives?

Edward P. Sloan, MD, MPH, FACEP E. Bradshaw Bunney, MD, FACEP Associate Professor Emergency Medicine Residency Director Department of Emergency Medicine University of Illinois College of Medicine at Chicago

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What is the optimal use of tPA given its reported efficacy and clinical effectiveness? If stroke patients present within 3 hours, should other therapies besides IV tPA be considered?

Edward P. Sloan, MD, MPH, FACEP Stroke Care After the 3 Hour IV tPA Window: What are the Diagnostic and Therapeutic Options?

Edward P. Sloan, MD, MPH, FACEP Andrew Asimos, MD, FACEP Adjunct Associate Professor Stroke Team Director Department of Emergency Medicine University of North Carolina School of Medicine at Chapel Hill

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What are the optimal neuroimaging modalities in non-IV tPA patients? What pharmacologic, interventional radiology, and operative techniques should be considered after (or during) the three hour IV tPA window?

Edward P. Sloan, MD, MPH, FACEP Stroke Patient Care in the Prehospital and ED Settings: Should EMS Triage & Inter-hospital Transfer Occur?

Edward P. Sloan, MD, MPH, FACEP Edward P. Sloan, MD, MPH Professor FERNE President & Board Chair Department of Emergency Medicine University of Illinois College of Medicine

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions Should pre-hospital stroke patients be directly triaged by EMS to specialty stroke centers? When should the ED inter-hospital transfer of stroke patients to specialty stroke centers occur?

Edward P. Sloan, MD, MPH, FACEP Current Updates on Ischemic Stroke, SAH, & ICH

Edward P. Sloan, MD, MPH, FACEP Stroke Patient and New Stroke Therapy Assessment: ED NIHSS & Stroke Scales Use

Edward P. Sloan, MD, MPH, FACEP Andrew Asimos, MD, FACEP Adjunct Associate Professor Stroke Team Director Department of Emergency Medicine University of North Carolina School of Medicine at Chapel Hill

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What is the role of the NIHSS in the ED evaluation and Rx of stroke pts? How can other stroke scales by simply utilized in order to assess the efficacy of stroke therapies?

Edward P. Sloan, MD, MPH, FACEP Emergency Department Neuroprotection: What are Optimal Strategies in Ischemic Stroke Patients?

Edward P. Sloan, MD, MPH, FACEP Andrew Asimos, MD, FACEP Adjunct Associate Professor Stroke Team Director Department of Emergency Medicine University of North Carolina School of Medicine at Chapel Hill

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What neuroprotection strategies prevent secondary brain injury following stroke? What is the information from the SAINT-I (and SAINT-II) clinical trials regarding the potential use of neuroprotectants such as NXY-059?

Edward P. Sloan, MD, MPH, FACEP The Diagnosis of SAH in ED Headache Patients: What Roles for CT Neuroimaging & Lumbar Puncture?

Edward P. Sloan, MD, MPH, FACEP E. Bradshaw Bunney, MD, FACEP Associate Professor Emergency Medicine Residency Director Department of Emergency Medicine University of Illinois College of Medicine at Chicago

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What are optimal headache patient diagnostic and treatment strategies based on current guidelines ? What is the role of LP (and CTA) in low risk headache patients whose CT is negative for blood?

Edward P. Sloan, MD, MPH, FACEP ED Hemorrhagic Stroke Patient Management: What Role for Operative Intervention and Factor VIIa?

Edward P. Sloan, MD, MPH, FACEP Edward P. Sloan, MD, MPH Professor FERNE President & Board Chair Department of Emergency Medicine University of Illinois College of Medicine

Edward P. Sloan, MD, MPH, FACEP Key Clinical Questions What is the role of operative intervention in ICH patients given the results of the STICH trial? What is the optimal management of anti-coagulated ICH patients and the potential role of factor VIIa?

Edward P. Sloan, MD, MPH, FACEP Housekeeping Content via website CME via the congress (US conversion in US) Evaluations…Please provide us feedback! Survey: help us to help you! Want more information? – websitewww.ferne.org

Edward P. Sloan, MD, MPH, FACEP Thank you to AstraZeneca Neuroscience for their support of these educational programs

Edward P. Sloan, MD, MPH, FACEP FERNE & Industry Support Collaboration in providing quality education programs Disease state education critical Independent grant process in US Unrestricted educational grants Content development independent of grant source

Edward P. Sloan, MD, MPH, FACEP Thank You Drs. Askitopoulou and Williams EuSEM Carla, Charri, Jon, Li, & FERNE staff The ERA staff All of the FERNE supporters AstraZeneca International and their staff All of you

Thank you ferne_eusem_2006_stroke_intro_100606_finalcd 5/7/ :53 AM Edward P. Sloan, MD, MPH, FACEP