LABBOX: GENERAL INTRODUCTION Distribution in Ireland Dublin, 16th May 2014

WHO IS LABBOX? our company Basic labware at basic prices supplier 2006 2007 2008 2009 2010 Basic labware at basic prices supplier Incorporated September 14, 2005 Offices and warehouse located in Mataró (at 40 km north Barcelona) Shareholders: Juan R. Jiménez (General Manager, Chemical Engineer-MBA) and Mónica San Martín (President, Business Angel-Private investor) Sales activity since March 2006 Product range: 4000 references (glassware, porcelain, plasticware, metalware, small equipment, reagents...), 90% of them with labbox branding Subsidiary office in France and distributors in 70 countries 2011 2012 2013 2014

MILESTONES our company 09/2005 Company incorporation 01/2006 5 employees 03/2006 First catalogue launch (200 references) 09/2007 First personalized catalogue for Portugal 10/2008 First tradeshow booth : Expoquimia 2008 (Barcelona) 11/2008 1000 customers in Spain 06/2009 Subsidiary office in France 03/2006 First customer, first order 10/2006 First distributor outside Spain : Portugal

MILESTONES our company 09/2009 First launch of our France catalogue 06/2010 First tradeshow outside Spain: Forum Labo 2010 (Paris) 10/2010 2000 customers in Spain 02/2011 First catalogue in English 02/2011 Launch of our Export Department 08/2009 Moving to new warehouse (1100 m2)

MILESTONES our company 03/2011 First tradeshow outside Europe : Arablab 2011 (Dubai) 06/2011 First catalogue of lab chemicals (Labkem brand) 03/2012 Distributors in 50 countries (now 70) 12/2012 40% of the turnover is done outside Spain 11/2012 25 employees 02/2013 Launch of LBX Instruments

MILESTONES our company 01/2014 12 versions of our catalogue (personalized with End-user prices for Spain, France, Switzerland, Morocco, Benelux, Scandinavia) Morocco Portugal Benelux Sweden, Norway Swizterland

OUR DISTRIBUTORS customers Active distributors worldwide

Technical specifications of LBG 3.3 glassware BOROSILICATE GLASS 3.3 glassware Technical specifications of LBG 3.3 glassware LBG 3.3 is a borosilicate glass with a minimum content in silica of 80% and a low expansion coefficient (3.3•10-6 K-1) included in the 3.3 borosilicate group, as defined in ISO 3585 standard. It is used in products where chemical and mechanical resistance is to be combined with resistance to sudden temperature changes. This particular combination of properties makes this type of glass the most used in labware. Physical and chemical properties Linear expansion coefficient (@ 20/300 ºC) 3.3•10-6 K-1 Strain point 520 ºC Annealing point 560 ± 10 ºC Softening point 820 ± 10 ºC Density 2.23 ± 0.02 g/cm3 Hydrolytic resistance (according to ISO 719, water at 98 ºC) Class 1 Hydrolytic resistance (according to ISO 720, water at 121 ºC) Class 1 Resistance to acids (according to ISO 1776, DIN 12116) Class 1 Resistance to alkalis (according to ISO 695) Class 2 Typical composition 80,4% in weight SiO2 13,0% in weight B2O3 4,2% in weight Na2O 2,4% in weight Al2O3

Some examples of linear temperature expansion coefficient BOROSILICATE GLASS 3.3 glassware What is a linear expansion coefficient? Some examples of linear temperature expansion coefficient Material •10-6 K-1 Ethanol 250 Mercury 61 Aluminum 23,1 Silver 18 Copper 16,6 Gold 14 Stainless steel 13 Glassware (regular) 8,5 Glassware (borosilicate) 3,3 Diamond 1 Quartz 0,33 TO REMEMBER “Borosilicate 3.3” in a type of glass All glassware manufacturers are using “Borosilicate 3.3” “LBG 3.3” is the name of our LABBOX “Borosilicate 3.3” de LABBOX. It is our brand

GENERAL LABWARE our products Products for routine applications in very different kind of laboratories (chemistry, life science, didactics, etc…) and not related with a particular technique

GENERAL LABWARE our products Different materials… porcelain soda glass PTFE polypropylene borosilicate glass 3.3 borosilicate glass 3.3 stainless steel polypropylene

Manufacturing Standards GENERAL LABWARE our products Manufacturing Standards Although the products seems very simple, manufacturing standards are to be followed, such as : Beakers: DIN 12331, ISO 3819 Polypropylene beakers: ISO 7056 Erlenmeyers: DIN 12380, ISO 1773

VOLUMETRIC MATERIAL our products Batch certificate is always available Class A always available (some products as well Class B)

VOLUMETRIC MATERIAL our products ISO, DIN… are defining Class A and B Usually Class A tolerance is half of Class B Most of the labbox VOLUMETRIC MATERIAL is only available on Class A

VOLUMETRIC MATERIAL our products Batch number

VOLUMETRIC MATERIAL our products Batch number Nominal value Tolerance Average value (batch) Standard deviation (batch) Test results Standard reference

VOLUMETRIC MATERIAL our products Standard Line ISO 1042 DIN 12664 Class A Borosilicate 3.3 Batch certificate Premium Line ISO 1042 DIN 12664 Class A Borosilicate 3.3 superior Batch certificate Batch number engraved Premium Line ISO 1042 DIN 12664 Class A Borosilicate 3.3 amber Batch certificate Batch number engraved Premium Line ISO 1042 DIN 12664 USP (tolerance > ISO) “Eichordnung” (“H”) Class A Borosilicate 3.3 superior Batch certificate Batch number engraved Premium Line ISO 1042 DIN 12664 USP (tolerance > ISO) Class A Borosilicate 3.3 superior Individual certificate Individual number engraved

Instruments and consumables for laboratory liquid handling our products Instruments and consumables for laboratory liquid handling

LIQUID HANDLING our products EASY: our LABBOX brand of liquid handling From the simple to the most sofisticated solution EASY 40+ Variable volume micropipette EASY 40 Smart Variable volume micropipette EASY 5 EASY 10 mini-micropipette EASY 8 EASY 20 Bottle top dispenser EASY 9 REVOLUTION Electronic micropipette EASY 60+ Electronic filling device EASY 30+ Fixed volume micropipette

LIQUID HANDLING our products Standard Line tips The best price Premium Line tips Human DNA free Certified DNAse, RNAse e PCR Inhibitors free Dyes free Sterile and non-sterile available Premium Line tips with filter Human DNA free Certified DNAse, RNAse e PCR Inhibitors free Dyes free Sterile and non-sterile available

LIQUID HANDLING our products Premium Line ULTRA LOW RETENTION tips: the best accuracy for critical molecular biology routine The sample retention within the tip is a important aspect of handling issues. Usually technicians were applying silicon inside tips but this may give contamination problems. labbox Premium Line ULR tips are manufactured with a new polymer (Novelle-Polypropylene) producing a slippery wall where no sample is retained . This polymer give a better performance once autoclaved. This method reduce 85% the sample retention and lower in more than 75% the standard volume deviation. They are specially recommended for molecular biology application, specially in DNA analysis, quantitative PCR and protein handling. Available with filter and without filter.

For organic synthesis techniques and other analytical techniques JOINTED GLASSWARE our products For organic synthesis techniques and other analytical techniques

FILTRATION AND SEPARATION our products Filter paper: LABBOX is associated with PRAT DUMAS, a French manufacturer with more than 100 years of experience and an old paper mill dating 1309

FILTRATION AND SEPARATION our products

FILTRATION AND SEPARATION our products

FILTRATION, SEPARATION and CONCENTRATION our products Once the required quality is decided, you only need to define the diameter and to choose between flat or folded paper:

FILTRATION, SEPARATION and CONCENTRATION our products Special papers: Glass microfiber paper: standard paper for determination of particle suspension (S.P.M.) in drinking or sewage water according to European standards (EN 872) and American standards (Standard Methods 2540D) Phase separating paper: hydrophobic paper for the fast separation of aqueous solutions from hydrofuge solvents Activated carbon filter paper: used to dispose benzene, toluene, xylene, ethyl benzene or other small organic molecules. Blotting paper for germination tests: it allows to determine the capacity of germination of seeds. Antibiotic control filter paper: used to determine the suitable antibiotic for a particular infection treatment. Blaine test filter paper: Used to determine the fineness of cement according to EN 196-6:2010 standard.

FILTRATION, SEPARATION and CONCENTRATION LABBOX filtration units our products LABBOX filtration units For Ø 47 mm For Ø 25 mm + + + For Ø 90 mm + For Ø 47 mm +

FILTRATION, SEPARATION and CONCENTRATION - VACUUM PUMP and EQUIPMENT - our products LABBOX is associated with the German manufacturer KNF LAB, one of the leading companies in laboratory vacuum pumps All vacuum pumps are membrane pumps 100% oil free

FILTRATION, SEPARATION and CONCENTRATION - VACUUM PUMP and EQUIPMENT - our products Laboratory applications: Rotary evaporation, distillation, sublimation, vacuum dry, gel dry, vacuum filtration, pressure filtration, sample preparation, liquid dosage…

FILTRATION, SEPARATION and CONCENTRATION - VACUUM PUMP and EQUIPMENT - our products Depending the materials used for manufacturing, you will find different versions of the same pump PPS pump-head and EPDM membrane: pump for neutral gases PPS pump-head and PTFE-coated diaphragm: pump for slightly aggressive gases PTFE pump-head and PTFE-coated diaphragm : pump for aggressive or corrosive gases

METALWARE and LABORATORY TOOLS our products Metalware, small tools and various items used on a daily basis at the laboratory: cutting tools, rods, spatulas, brushes, trays…

MICROBIOLOGY and PATHOLOGY our products Petri dishes Microscope slides and accessories Reagents for biochemistry, histology dies…

MICROBIOLOGY and PATHOLOGY our products Polystyrene disposable Petri dishes Available in 55, 90, 100, 120 and 150 Ø mm and square-shape 120 x 120 mm Aseptic or sterilized by irradiation With our without vents (ventilation holes) Without compartments or with 2/3 compartments CE-IVD Marking (European directive for in-vitro diagnostic products) Non disposable glass Petri dishes are available Sterilization certificate CE Conformity Declaration

MICROBIOLOGY and PATHOLOGY our products Microscope slides: 4 qualities to satisfy any kind of customers BASIC LINE The economic option For education and routine applications in veterinary, urine analysis Clearglass, pre-cleaned Cut or ground edges STANDARD LINE The quality/price option For all kind of applications Clearglass, pre-cleaned Cut or ground edges PREMIUM LINE Superior quality at an affordable price For applications in pathology, histology, cytology, and other ones where a higher quality is required Clearglass, pre-cleaned Beveled edges SUPER WHITE LINE The best quality: made of pure white glass For the most for the most exigent applications in pathology, histology, cytology, etc. The composition of pure white glass with very low contents of iron, grants exceptional optical properties Beveled edges

MICROSCOPES and STEREOMICROSCOPES our products LABBOX is associated with MOTIC, a leader manufacturer of microscope components and equipments. Motic have manufacturing plants and warehouses in Canada, Germany, Hong-Kong, Spain and United States

BOTTLES and SAMPLE CONTAINERS our products In different kind of glass and plastic material From 3,5 ml up to 50 l Narrow mouth, wide mouth, screw cap, round shape, square shape, aseptic, sterile, sealable, with thiosulfate, transparent, etc… …one kind of bottle for each application

BOTTLES and SAMPLE CONTAINERS Laboratory bottle with ISO thread our products Laboratory bottle with ISO thread Commonly used for microbiology culture media preparation Made of borosilicate glass 3.3 Completely autoclavable at 140 ºC (caution: always autoclaving not screwing the cap) GL 45 thread, according to ISO 4796 (suitable for bottle dispensers such as EASY20 labbox or similar from other brands) Pouring ring and cap in blue PP, suitable up to 140 ºC For higher temperatures (up to 200 ºC) a red ring made in PBTP and a red cap made in silicone-PTFE coated is available For photosensitive products, amber version is available

BOTTLES and SAMPLE CONTAINERS our products Versatility: different bottles with PP28 thread to combine with different caps Amber glass Transparent glass Amber PET Transparent PET HDPE + Counter drop screw Regular cap Dropper screw cap

BOTTLES and SAMPLE CONTAINERS our products Sealable bottles: to ensure the security of the samples Bottles include a ring on the cap and on the bottle Once closed, the sealing can only be opened if broken Security sealing are available in plastic and stainless steel wire Each sealing have a single serial number printed

CHROMATOGRAPHY VIALS our products Vials 12 x 32 mm (1,8-2 mL) Crimped or screw cap Transparent or amber You will find this kind of vial in the most common equipements such as: Agilent (HP) 1050/1100/1200/1090/7673A CTC LC PAL, GC PAL and COMBI PAL Merck-Hitachi Perkin Elmer Autosystem/XL/Clarus/ISS 100/ISS 200/Integral 4000 Shimadzu GC and LC autosamplers Spark Thermo Scientific GC TRACE/AS3000/AI3000/AS800/TriPlus and HPLC SpectraSystem AS3500/AS3000/AS1000/Surveyor/Accela Varian GC Autosamplers 8000/8100/8410 and LC Autosamplers 9090/9095/PROSTAR Waters Alliance/Acquity Nota: brands and models are indicated here as a reference. The same model may accept different types of vials racks and they are not always compatible with vials 12 x 32 mm

CENTRIFUGATION and TEST TUBES our products

STIRRERS and ACCESSORIES our products LBX Instruments Brand

THERMOREGULATION, COMBUSTION and CALCINATION our products Porcelain crucibles: up to 1150 ºC Quartz crucibles: up to 1100 ºC Alumina crucibles: up to 1750 ºC Platinum crucibles: up to 1700 ºC

THERMOREGULATION, COMBUSTION and CALCINATION our products Technical specifications of porcelain Thermal Shock Resistance: Average coefficient of expansion from 20 ºC to 200 ºC is 3.56 x 10-5 , gradually increasing to 4.69 x 10-5 at 1000 ºC. To prevent thermal stress cracks on porcelain ware, labbox strongly recommends a heating/cooling rate not to exceed 200 ºC/hour. Resistance to Chemical Action: The resistance to acids and alkalis is excellent, except for hydrofluoric acid. Prolonging labware life: Follow gradual heating and cooling rates. Use an oven or hot plate as an intermediate step when quicker heating/cooling rates are required. Gradually increase flame intensity when using a gas burner. Avoid contact of heated ware with a cold surface. Carefully inspect your labware prior to each use Do not use any product that appears defective.

THERMOREGULATION, COMBUSTION and CALCINATION our products Technical specifications of alumina Made of pure aluminum oxyde (AL2O3 at 99.6%) Used in metallurgy and other fields where high temperatures combined with high chemical resistance are required. It can be used in reducing or oxidizing atmospheres. Inert in hydrogen or carbonic atmospheres. Suitable for melting glass, borosilicate glass included. Recommended to with refractory metals such as molybdenum, platinum, tungsten, tantalum, rhodium and iridium. To avoid cracks due to thermal stress on alumina, labbox recommended the speed of warming / cooling does not exceed 150 ° C / hour.

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