Il controllo dell’espressione genica

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Presentation transcript:

Il controllo dell’espressione genica Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Operoni batterici Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

OPERONE LAC Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Repressione da catabolita operone Lac CAP: Catabolite Activator Protein Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Si conoscono I seguenti tipi di alleli per l’operone Lac: Gene REPRESSORE: Is SUPER REPRESSORE; I+ inducibile; I- costitutivo Operatore: Oc costitutivo; O+ inducibile Strutturali, Z+ e Y+ Quali dei seguenti genotipi produrranno beta-Galattosidasi e permeasi in presenza di Lattosio? I*O*Z*Y*; I-OcZ*Y*; IsOcZ*Y*; IsO*Z*Y*; I-O*Z*Y*; Genetica Di Leonardo 2012

(a) I+O+Z+Y+/I+O+Z+Y+, (b) I+O+Z+Y+/I+OcZ+Y+, 19.5 Groups of alleles associated with the lactose operon are as follows (in order of dominance for each allelic series): repressor, Is (superrepressor), I+ (inducible), and I- (constitutive); operator, Oc (constitutive, cis- dominant) and O+ (inducible, cis-dominant); structural, Z+ and Y+. (a) Which of the following genotypes will produce b-galactosidase and b-galactoside permease if lactose is present: (1) I+O+Z+Y+, (2) I-OcZ+Y+, (3) IsOcZ+Y+, (4) IsO+Z+Y+, and (5) I-O+Z+Y+? (b) Which of the above genotypes will produce b-galactosidase and b-galactoside permease if lactose is absent? Why? 19.8. For each of the following partial diploids indicate whether enzyme synthesis is constitutive or inducible (see Problem 19.5 for dominance relationships): (a) I+O+Z+Y+/I+O+Z+Y+, (b) I+O+Z+Y+/I+OcZ+Y+, (c) I+OcZ+Y+/I+OcZ+Y+, (d) I+O+Z+Y+/I-O+Z+Y+, (e) I-O+Z+Y+/I-O+Z+Y+. Why? Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Regolazione Biosintesi triptofano: operone reprimibile Genetica Di Leonardo 2012

Operone triptofano: reprimibile Genetica Di Leonardo 2012

Organizzazione genetica operone TRP di E.Coli Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Regolazione dell’operone TRP per ATTENUAZIONE Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

Genetica Di Leonardo 2012

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