Volume 20, Issue 8, Pages (August 2019)

Slides:

Advertisements

Similar presentations

Volume 370, Issue 9586, Pages (August 2007)

Advertisements

Su K. Metcalfe, MD, MPH, Michael T

Efficacy and Safety of Pemetrexed Maintenance Therapy versus Best Supportive Care in Patients from East Asia with Advanced, Nonsquamous Non-small Cell.

Volume 11, Issue 4, Pages (April 2012)

Volume 388, Issue 10058, Pages (November 2016)

Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants Ugo Pastorino, MD, Roberto Boffi, MD, Alfonso Marchianò, MD,

Carcinoma NOS is a Common Histologic Diagnosis and is Increasing in Proportion Among Non-small Cell Lung Cancer Histologies Sai-Hong Ignatius Ou, MD,

Two Classic Lyrics Joined by a Contemporary Tune—Environmental Pro-Carcinogen Exposure and Genetic Susceptibility in Lung Cancer Risk Ping Yang, MD,

Volume 19, Issue 2, Pages (February 2018)

Perioperative versus Preoperative Chemotherapy with Surgery in Patients with Resectable Squamous Cell Carcinoma of Esophagus Yang Zhao, MD, ZhiJun Dai,

Gender differences in non–small-cell lung cancer survival: an analysis of 4,618 patients diagnosed between 1997 and 2002 Antonio L Visbal, MD, Brent.

Volume 5, Issue 4, Pages (April 2006)

Volume 13, Issue 12, Pages (December 2012)

The Value of a Symptom Cluster of Fatigue, Dyspnea, and Cough in Predicting Clinical Outcomes in Lung Cancer Survivors Andrea L. Cheville, MD, MSCE,

Volume 11, Issue 6, Pages (June 2010)

Role of Postoperative Radiotherapy in Pathologic Stage IIIA (N2) Non–Small Cell Lung Cancer in a Prospective Nationwide Oncology Outcomes Database Alex.

Effects of a Nationwide Predialysis Educational Program on Modality Choice, Vascular Access, and Patient Outcomes Eduardo Lacson, MD, MPH, Weiling Wang,

Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas Yiliang Zhang, MD, Rui Wang, MD, PhD, Yuan.

Andrea Ganna, PhD, Prof Erik Ingelsson, MD The Lancet

Prognostic Significance of C-Reactive Protein and Smoking in Patients with Advanced Non-small Cell Lung Cancer Treated with First-Line Palliative Chemotherapy

Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study Matthew Waxman, MD,

Shidan Wang, BS, Lin Yang, MD, Bo Ci, BS, Matthew Maclean, BS, David E

Validation of the Stage Groupings in the Eighth Edition of the TNM Classification for Lung Cancer Xizhao Sui, MD, Wei Jiang, MD, Haiqing Chen, MD, Fan.

Role of Postoperative Radiotherapy in Pathologic Stage IIIA (N2) Non–Small Cell Lung Cancer in a Prospective Nationwide Oncology Outcomes Database Alex.

Volume 10, Issue 6, Pages (June 2009)

Susan C. Scott, MD, Nathan A. Pennell, MD, PhD

Endpoints in Phase II Trials for Advanced Non-small Cell Lung Cancer

Trends in Subpopulations at High Risk for Lung Cancer

Volume 2, Issue 9, Pages (September 2015)

Comparison of Segmentectomy and Lobectomy in Stage IA Adenocarcinomas

Prognostic Impact of Newly Proposed M Descriptors in TNM Classification of Non–Small Cell Lung Cancer Junghoon Shin, MD, Bhumsuk Keam, MD, PhD, Miso.

The Influence of Body Mass Index on Overall Survival Following Surgical Resection of Non–Small Cell Lung Cancer Boris Sepesi, MD, Kathryn A. Gold, MD,

Prognostic Factors in Completely Resected Node-Negative Lung Adenocarcinoma of 3 cm or Smaller Jung-Jyh Hung, MD, PhD, Yi-Chen Yeh, MD, Yu-Chung Wu,

Treatment Outcomes by Tumor Histology in Eastern Cooperative Group Study E4599 of Bevacizumab with Paclitaxel/Carboplatin for Advanced Non-small Cell.

Samuel J. Wang, MD, PhD, C David Fuller, MD, Charles R. Thomas, MD

Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants Ugo Pastorino, MD, Roberto Boffi, MD, Alfonso Marchianò, MD,

Volume 13, Issue 12, Pages (December 2012)

Pretreatment Quality of Life Is an Independent Prognostic Factor for Overall Survival in Patients with Advanced Stage Non-small Cell Lung Cancer Yingwei.

Regional Emphysema Score Predicting Overall Survival, Quality of Life, and Pulmonary Function Recovery in Early-Stage Lung Cancer Patients Jie Dai, PhD,

Lung Cancer and Prognosis in Taiwan: A Population-Based Cancer Registry Bing-Yen Wang, MD, Jing-Yang Huang, Ching-Yuan Cheng, MD, Ching-Hsiung Lin, MD,

Improved Lymph Node Staging in Early-Stage Lung Cancer in the National Cancer Database Seth B. Krantz, MD, Waseem Lutfi, BS, Kristine Kuchta, MS, Chi-Hsiung.

Jeffrey Bradley, MD, Issam El Naqa, PhD Journal of Thoracic Oncology

Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non–Small Cell Lung Cancer: NCCTG N0028 (Alliance)

Volume 388, Issue 10058, Pages (November 2016)

All-cause mortality risk associated with long-term exposure to ambient PM2·5 in China: a cohort study Prof Tiantian Li, PhD, Yi Zhang, MPH, Jiaonan Wang,

Ellen Kim, MD, MPH, Siran Koroukian, PhD, Charles R. Thomas, MD

Prophylactic Cranial Irradiation for Patients with Surgically Resected Small Cell Lung Cancer Jianlin Xu, MD, Haitang Yang, MD, Xiaolong Fu, MD, Bo Jin,

Volume 20, Issue 1, Pages (January 2019)

Volume 9, Issue 4, Pages (April 2008)

Jeffrey T. Yorio, MD, Yang Xie, PhD, Jingsheng Yan, PhD, David E

Jessica J. Lin, MD, Stephanie Cardarella, MD, Christine A

Daniel Morgensztern, MD, Boone Goodgame, MD, Maria Q

Volume 5, Issue 4, Pages (April 2018)

Volume 375, Issue 9726, Pages (May 2010)

Volume 373, Issue 9658, Pages (January 2009)

Volume 19, Issue 2, Pages (February 2018)

Thoracoscopic Lobectomy Produces Long-Term Survival Similar to That with Open Lobectomy in Cases of Non–Small Cell Lung Carcinoma: A Propensity-Matched.

The Role of Extent of Surgical Resection and Lymph Node Assessment for Clinical Stage I Pulmonary Lepidic Adenocarcinoma: An Analysis of 1991 Patients

Volume 373, Issue 9672, Pages (April 2009)

Should Patient-Rated Performance Status Affect Treatment Decisions in Advanced Lung Cancer? Esther Dajczman, RN, MScA, Goulnar Kasymjanova, MD, PhD,

Shannon M. Dunlay, MD, MS, Quinn R. Pack, MD, Randal J

Long-Term Results of Radiofrequency Ablation Treatment of Stage I Non-small Cell Lung Cancer: A Prospective Intention-to-Treat Study Marcello Carlo Ambrogi,

The Prognostic Impact of Cigarette Smoking on Patients with Non-small Cell Lung Cancer Ryo Maeda, MD, Junji Yoshida, MD, PhD, Genichiro Ishii, MD, PhD,

Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study Dr Daniel W Belsky, PhD, Prof Malcolm.

Systematic Evaluation of Genetic Variants in Three Biological Pathways on Patient Survival in Low-Stage Non-small Cell Lung Cancer V. Shane Pankratz,

Michael Hsie, MD, Stefania Morbidini-Gaffney, MD, Leslie J

The impact of concomitant pulmonary hypertension on early and late outcomes following surgery for mitral stenosis Bo Yang, MD, PhD, Christina DeBenedictus,

Efficacy and Safety of Cisplatin/Pemetrexed Versus Cisplatin/Gemcitabine as First-Line Treatment in East Asian Patients with Advanced Non-small Cell Lung.

Pleurodesis for primary spontaneous pneumothorax – Authors' reply

Treatment Outcomes by Tumor Histology in Eastern Cooperative Group Study E4599 of Bevacizumab with Paclitaxel/Carboplatin for Advanced Non-small Cell.

Presentation transcript:

Volume 20, Issue 8, Pages 1098-1108 (August 2019) 5-year overall survival in patients with lung cancer eligible or ineligible for screening according to US Preventive Services Task Force criteria: a prospective, observational cohort study Yung-Hung Luo, MD, Lei Luo, PhD, Jason A Wampfler, BS, Yi Wang, MD, Dan Liu, MD, Prof Yuh-Min Chen, MD, Prof Alex A Adjei, MD, Prof David E Midthun, MD, Prof Ping Yang, MD The Lancet Oncology Volume 20, Issue 8, Pages 1098-1108 (August 2019) DOI: 10.1016/S1470-2045(19)30329-8 Copyright © 2019 Elsevier Ltd Terms and Conditions

Figure 1 Multivariable Cox proportional hazard models of overall survival in patients meeting USPSTF screening criteria versus long-term quitters (A) Hospital cohort. (B) Community cohort. Results are presented for unmatched and matched analyses for age at diagnosis and pack-years. Multivariable Cox proportional hazards models were used to adjust for age, sex, race, smoking status, pack-years smoked, tumour histology and stage, and treatment modalities. USPSTF=US Preventive Services Task Force. The Lancet Oncology 2019 20, 1098-1108DOI: (10.1016/S1470-2045(19)30329-8) Copyright © 2019 Elsevier Ltd Terms and Conditions

Figure 2 Kernel density plots showing the balance improvement for age at diagnosis and pack-years smoked between patients meeting USPSTF screening criteria and long-term quitters (A) Hospital cohort. (B) Community cohort. The density of the kernel density plot represents the kernel density estimate of the probability function of a variable from patients (eg, age or pack-year), which is interpreted as a probability differential. Results are presented for unmatched and matched analyses. USPSTF=US Preventive Services Task Force. The Lancet Oncology 2019 20, 1098-1108DOI: (10.1016/S1470-2045(19)30329-8) Copyright © 2019 Elsevier Ltd Terms and Conditions

Figure 3 Kaplan-Meier curves of overall survival of the younger age group and USPSTF group (A) 5-year overall survival in the hospital cohort. (B) 5-year overall survival in the community cohort. USPSTF=US Preventive Services Task Force. The shading represents 95% CIs for the survival curves. The Lancet Oncology 2019 20, 1098-1108DOI: (10.1016/S1470-2045(19)30329-8) Copyright © 2019 Elsevier Ltd Terms and Conditions

Figure 4 Multivariable Cox proportional hazard models of patients meeting USPSTF screening criteria versus the younger age group (A) Hospital cohort. (B) Community cohort. USPSTF=US Preventive Services Task Force. The Lancet Oncology 2019 20, 1098-1108DOI: (10.1016/S1470-2045(19)30329-8) Copyright © 2019 Elsevier Ltd Terms and Conditions