Changes in urinary albumin excretion rate in relation to baseline (top), cross-sectional values of GFR (middle), and MABP (bottom) during treatment with placebo (♦), irbesartan 150 mg (▪), and irbesartan 300 mg (▴) and 1 month after withdrawal of all antihypertensive treatment. Changes in urinary albumin excretion rate in relation to baseline (top), cross-sectional values of GFR (middle), and MABP (bottom) during treatment with placebo (♦), irbesartan 150 mg (▪), and irbesartan 300 mg (▴) and 1 month after withdrawal of all antihypertensive treatment. Steen Andersen et al. Dia Care 2003;26:3296-3302 ©2003 by American Diabetes Association