Vorozole treatment-associated changes in protein abundance of multiple antigens. Vorozole treatment-associated changes in protein abundance of multiple.

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Vorozole treatment-associated changes in protein abundance of multiple antigens. Vorozole treatment-associated changes in protein abundance of multiple antigens. Mammary cancers (A) or normal rat mammary epithelium (B) were rapidly removed from five individual rats and fixed for immunoreactivity analysis to determine possible protein targets of vorozole. Five sections were cut and stained for each tumor sample. Proteins were detected by incubating with specific primary antibodies and secondary antibodies (Materials and Methods) conjugated to a fluorescence dye (Cy2, green; Cy3, red). Samples were observed by confocal microscopy and quantitated. Averages and deviations representing at least five tumors and five sets of normal glands are presented. Yan Lu et al. Cancer Prev Res 2013;6:1151-1161 ©2013 by American Association for Cancer Research