Effect of rosuvastatin pretreatment on myocardial damage after coronary surgery: A randomized trial Vito A. Mannacio, MD, Domenico Iorio, MD, Vincenzo.

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Presentation transcript:

Effect of rosuvastatin pretreatment on myocardial damage after coronary surgery: A randomized trial Vito A. Mannacio, MD, Domenico Iorio, MD, Vincenzo De Amicis, MD, Francesco Di Lello, MD, F. Musumeci, MD The Journal of Thoracic and Cardiovascular Surgery Volume 136, Issue 6, Pages 1541-1548 (December 2008) DOI: 10.1016/j.jtcvs.2008.06.038 Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Rate of postoperative myocardial disease in high-risk patients. The last column shows cumulative results in high-risk patients of the 2 study arms. EF, Ejection fraction; MI, myocardial infarction. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 1541-1548DOI: (10.1016/j.jtcvs.2008.06.038) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Mean plasma troponin I (Tn I) changes after cardiac surgery as a percentage of maximal level. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 1541-1548DOI: (10.1016/j.jtcvs.2008.06.038) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Results of multivariate analysis showing the effect of rosuvastatin (RSV) pretreatment in high-risk patients. OR, Odds ratio; CI, confidence interval; EF, ejection fraction; MI, myocardial infarction. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 1541-1548DOI: (10.1016/j.jtcvs.2008.06.038) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions