Schematic presentation of the main transductional pathways in phagocytes. Schematic presentation of the main transductional pathways in phagocytes. Due.

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Schematic presentation of the main transductional pathways in phagocytes. Schematic presentation of the main transductional pathways in phagocytes. Due to space limitation, not all routes and regulatory signals are shown. The main abbreviations are given in the text. Additional abbreviations: R1, R2, R′, receptors; L1, L2, L′, ligands; Ac, adenyl cyclase; cAMP, cyclic AMP; Cs, calciosome; CaM-K/CaM-Pase, calmodulin-dependent kinase/phosphatase; GAP, GTPase-activating protein; GRF, guanine regulatory exchange factor; GP, heterotrimeric G protein; GPL, glycurophospholipids; MLCK, myosin light-chain kinase; NR-PTK/PTK, nonreceptor/receptor protein tyrosine kinase; P, phosphorylation; PC, phosphatidylcholine. Marie-Thérése Labro Clin. Microbiol. Rev. 2000; doi:10.1128/CMR.13.4.615