Association between RB pathway alterations and poor prognosis in early-stage lung adenocarcinoma patients. Association between RB pathway alterations and.

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Association between RB pathway alterations and poor prognosis in early-stage lung adenocarcinoma patients. Association between RB pathway alterations and poor prognosis in early-stage lung adenocarcinoma patients. A, Kaplan–Meier curves of disease-free survival (DFS) for early-stage lung adenocarcinoma patients in the discovery cohort (n = 129). The survival curves of the patients with RB pathway mutations and the remaining patients are shown in red and blue, respectively. The log-rank P value and q value are also shown. B, DFS curve for early-stage lung adenocarcinoma patients in the validation cohort (n = 59). Otherwise, as in A. C, DFS curve for late-stage lung adenocarcinoma patients in the discovery cohort (n = 27). Otherwise, as in A. D, DFS curve for late-stage lung adenocarcinoma patients in the validation cohort (n = 13). Otherwise, as in A. Seongmin Choi et al. Clin Cancer Res 2015;21:2613-2623 ©2015 by American Association for Cancer Research