Fig. 5 Nucleotide variation in wild-caught, South Carolina colony and inbred strains of P. leucopus. Nucleotide variation in wild-caught, South Carolina.

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Fig. 5 Nucleotide variation in wild-caught, South Carolina colony and inbred strains of P. leucopus. Nucleotide variation in wild-caught, South Carolina colony and inbred strains of P. leucopus. The bottom panel depicts the physical density of SNPs in the low-pass sequenced wild individuals smoothed using a 10-Mb normal kernel. The middle panel depicts the probability of heterozygosity per SNP locus smoothed using a 2-Mb normal kernel for three wild caught animals. The top panel depicts the smoothed probability of heterozygosity per SNP locus for three colony mice. Red, inbred strain GS16A1 from the Peromyscus Genetic Stock Center; pink, outbred stock housed at the Rocky Mountain Laboratories; and blue, the reference individual described in Materials and Methods. In both RMNL and the reference individual, runs of homozygosity are regions that are identical by descent, consistent with those animals coming from closed colonies. The cyan circle is the approximate location of human leukocyte antigen located on the fusion chromosome. Anthony D. Long et al. Sci Adv 2019;5:eaaw6441 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).